Clinical trials: Routine care
Multiple Sclerosis, Clinically Isolated Syndrome
Autoimmune Intervention Mastery Course Study
The goal of this project is to critically evaluate the effectiveness of using an online program to improve diet and self-care in patients with multiple sclerosis (MS), clinically isolated syndrome (CIS), fibromyalgia, post acute…
- Conditions
- Multiple Sclerosis, Clinically Isolated Syndrome, Fibromyalgia, Post Acute Sequelae of COVID-19
- Trial name
- AIM (NCT05057676)
- Testing
- Immediate Autoimmune Intervention Mastery Course (AIM), Immediate Question and Answer sessions. (AIM Q and A sessions), Delayed Autoimmune Intervention Mastery Course (delayed AIM course)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Terry L. Wahls
Adult Growth Hormone Deficiency, Mild Traumatic Brain Injury
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
The purpose of this study is to determine whether growth hormone replacement therapy (GHRT) is effective versus placebo in the improvement of Quality of Life in patients with adult growth hormone deficiency (AGHD) and mild…
- Trial name
- GRIT (NCT04867317)
- Testing
- Somatropin
- Where
- 16 sites in United States
- Volunteers
- 172 people
- Sponsor
- VA Office of Research and Development
Post-concussive Symptoms, Traumatic Brain Injury
Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
This is a Phase II randomized trial designed to describe the magnitude of change between baseline and follow-up outcomes for symptom surveys and a battery of neuropsychological tests administered at time points corresponding…
- Trial name
- HOPPS (NCT01306968)
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United States
- Volunteers
- 79 people
- Sponsor
- U.S. Army Medical Research and Development Command
Rheumatoid Arthritis
JAKPOT (JAK Inhibitors and Predictors of Outcome in RheumaToid Arthritis)
Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease associated with inflammation and destruction of joints and systemic effects, which result in significant impact on patient's quality of life and function.
- Trial name
- JAKPOT (NCT04084223)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Montpellier
Bariatric Surgery Candidate, Obesity, Morbid
Prophylactic Use of Noninvasive Ventilation in the Postoperative Period of Bariatric Surgery
Comorbidities associated with severe obesity determine an important public health problem. Few methods are considered potentially effective for the treatment of severe obesity and the clinical relevance of bariatric surgery is…
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Ventilatory Failure
- Trial name
- NCT04805476
- Testing
- Non invasive mechanical ventilation, GP
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
PONV
Risk Factors for Postoperative Nausea and Vomiting After Nasal Surgery Under General Anesthesia
The goal of this observational study is to learn how often postoperative nausea and vomiting occur in adults undergoing nasal surgery under general anesthesia and to identify factors associated with these events.
- Trial name
- N-PONV (NCT07749079)
- Volunteers
- 1,000 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Rotator Cuff Repair
Unexpected Positive Cultures in Rotator Cuff Revision Surgery
In the context of rotator cuff re-intervention, the impact of Unexpected Positive Cultures (UPC) is not documented, and their management has not been studied, particularly regarding indications for antibiotic therapy, which is…
- Trial name
- POCICO (NCT06257979)
- Testing
- This study is with minimal risk and minimal constraints due to the addition of questionnaires
- Where
- 8 sites in France
- Volunteers
- 132 people
- Sponsor
- Elsan
Attention Deficit Hyperactivity Disorder (ADHD)
Internet-Based Behavioural Parent Training Intervention for Children With Attention Deficit/Hyperactivity Disorder
This study aims to investigate the effectiveness of an Internet-based behavioural parent training intervention on children's ADHD symptoms and children's and parents' mental health status.
- Trial name
- NCT06170996
- Testing
- Internet-based behavioral parent training (I-BPT)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wuhan Mental Health Centre
Hypertrophic Scars
Effect of Cryotherpy on Hypertrophic Scar
Purpose of the study: The purpose of the study is to evaluate the therapeutic effect of cryotherpy in treating hypertrophic scar. It will be hypothesized that: Cryotherapy may not have an effect on hypertrophic scar.
- Trial name
- NCT04532840
- Testing
- cryotherapy (Gymna Cryoflow ICE-CT), Exercising, Positioning and splinting, Pressure Therapy and Massage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zakria Mowafy
Cerebral Palsy
Upper Extremity Function, School Performance, and Academic Success in Children With Cerebral Palsy
The aim of this study is to investigate the relationship between upper extremity functionality and school-related outcomes, including academic achievement, school performance, and perceived academic success in school-aged…
- Trial name
- CP-SCHOOL (NCT07561710)
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Yeditepe University
Hepatitis C
Hepatitis C Screening Alerts
The objective of this study is to evaluate whether alerts that identify patients without hepatitis C infection to healthcare providers and clinic staff can increase the uptake of screening for hepatitis C.
- Trial name
- NCT05710120
- Testing
- Hepatitis C Screening Alerts in CHORUS™, Standard of Care
- Where
- United States
- Volunteers
- 125,706 people
- Sponsor
- Epividian
Trauma
Effect of Family Member's Massage Therapy on the Vital Signs and Glasgow Coma Scale Score
The effect of family member's massage therapy on the Vital signs and Glasgow Coma Scale Score of hospitalized patients in Intensive Care Unit: A Triple-blinded Randomized controlled Clinical Trial Study
- Trial name
- NCT01909882
- Testing
- Massage therapy
- Where
- Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Primiparous Pregnant Women in the Last Trimester
The Effect of Neonatal Care Education Given to Primiparous Mothers in the Last Trimester on Mothers' Self-Efficacy Perception, Prenatal and Maternal Bonding in the Early Postpartum Period
This study was conducted using a pre-test-post-test randomized controlled experimental design to investigate the effects of neonatal care education given to primiparous mothers in the last trimester on their self-efficacy…
- Trial name
- NCT07547579
- Testing
- Newborn Care Education
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Breastfeeding
An Innovative Continuum of Care to Promote Exclusive Breastfeeding
Malnutrition and non optimal breastfeeding is one the the major cause of high infant morbidity and mortality in a developing country like Pakistan.
- Trial name
- NCT05951868
- Testing
- Continuum of support on breastfeeding.
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
This clinical trial studies the effect of cancer directed therapy given at-home versus in the clinic for patients with cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the…
- Conditions
- Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma, Advanced Bladder Carcinoma, Advanced Breast Carcinoma
- Trial name
- NCT05969860
- Testing
- Clinical Encounter, Home Health Encounter, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Mayo Clinic
Behavior, Health
Supportive and Dignified Maternity Care in Public Health Facilities
Brief Summary Poor psychosocial support and demeaning care during childbirth in health facilities are common worldwide, particularly in low- and middle-income countries.
- Trial name
- SDMC (NCT06808360)
- Testing
- Supportive and Dignified Maternity Care
- Where
- Pakistan
- Volunteers
- 314 people
- Sponsor
- Aga Khan University
Nipple Pain During Lactation, Comfort
The Effect of Nursing Pillow Use on Nipple Pain and Comfort
Many factors influence breastfeeding. Nipple pain and comfort are among these factors and can negatively impact the breastfeeding process. A nursing pillow can relieve nipple pain and increase comfort.
- Trial name
- NCT07082959
- Testing
- Nursing Pillow
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Infertility, Obesity
Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome
Hypothesis: The investigators hypothesize that pulsatile FSH intravenous administration to women with obesity will correct the Reprometabolic Syndrome (RMS) luteal deficiency phenotype.
- Conditions
- Infertility, Obesity, Diminished Ovarian Reserve (DOR), Diminished Ovarian Reserve
- Trial name
- NCT06414096
- Testing
- Follicle Stimulating Hormone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Term Pregnancy, Labour Induction
Effect of Membrane Sweeping at Term on Duration of Onset of Labour at Tertiary Care Hospital (EMSTDOLTCH)
The goal of this clinical trial is to learn whether membrane sweeping can help start labour naturally and improve delivery outcomes in women with term pregnancy.
- Conditions
- Term Pregnancy, Labour Induction, Delayed Onset of Labour, Post Term Pregnancy
- Trial name
- EMSTDOLTCH (NCT07615946)
- Testing
- membrane sweeping, Routine Vaginal examination
- Where
- Pakistan
- Volunteers
- 214 people
- Sponsor
- Kharadar General Hospital
Surgical Site Infection
Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections
The purpose of this study was to compare the rate of surgical site infections in patients randomized to Irrisept versus SoC, who had an open abdominal laparotomy for abdominal trauma or acute surgical abdomen.
- Trial name
- NCT02255487
- Testing
- IrriSept System, No Intervention - Standard of Care (SoC) only
- Where
- 17 sites in United States
- Volunteers
- 627 people
- Sponsor
- Irrimax Corporation
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