Clinical trials: Routine care
Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma
Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery
This pilot trial studies how well single photon emission computed tomography (SPECT)/computed tomography (CT) with technetium Tc-99m sulfur colloid works in measuring liver function in patients with liver cancer that has or has…
- Conditions
- Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, Stage IV Liver Cancer, Stage IVA Liver Cancer
- Trial name
- NCT02881554
- Testing
- Computed Tomography, Single Photon Emission Computed Tomography, Technetium Tc-99m Sulfur Colloid
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Washington
Hormone Refractory Prostate Cancer, Bone Metastases
A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastases
ALSYMPCA (ALpharadin in SYMPtomatic Prostate CAncer) is an international Phase III clinical study to evaluate the efficacy and safety of Radium-223 dichloride in patients with hormone refractory prostate cancer and skeletal…
- Trial name
- ALSYMPCA (NCT00699751)
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223), Best standard of care (BSoC)
- Where
- 134 sites in United States, Australia and 17 more
- Volunteers
- 921 people
- Sponsor
- Bayer
Conscious Sedation
Nasal Versus Oral Midazolam Sedation in Routine Pediatric Dental Care
The general objective of the study is to compare the efficacy of administering midazolam orally as syrup versus nasally with nasal atomizer.
- Trial name
- NCT02679781
- Testing
- oral midazolam, nasal midazolam
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Adverse Events
Retrospective Independent Safety Review of Closed Irrisept Study
The purpose of CLP-01 was to complete the safety endpoint of the closed trial and ensure that all safety data generated by IRR-CT-901-2013-01 was accounted for and accurately identified, verified, and independently adjudicated.
- Trial name
- NCT05359666
- Testing
- Irrisept, Standard of Care
- Where
- 17 sites in United States
- Volunteers
- 592 people
- Sponsor
- Irrimax Corporation
COVID 19, Rehabilitation
Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients
Conventional in-hospital mobility programs are challenging to deliver to hospitalized infected patients (e.g., COVID-19) due to infection risk to staff, staffing shortages, and potential exposure of other patients.
- Conditions
- COVID 19, Rehabilitation, Inpatient, Hospitalized
- Trial name
- NCT04743401
- Testing
- Tele-exergaming Tablet
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Urinary Retention
Assessing Pyridium for Post-Sling Urinary Retention
There has been preliminary data showing that pyridium can decrease the risk of difficulty urinating after midurethral sling. This study is designed to have two groups of patients.
- Trial name
- NCT03302936
- Testing
- Phenazopyridine
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Long-Term Care, Long-term Care Facility
Effect of Empathy-Based Program on Nursing Assistants in Long-term Care Facilities
This randomized controlled trial aims to explore the impact of an Empathy-Based Program on the level of empathy among nursing assistants in a long-term care facility.
- Trial name
- NCT07044492
- Testing
- Virtual Reality (VR) with Debriefing
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
PreDiabetes
CGM Plus GEM in Prediabetes
This study is designed to look into the effect of a lifestyle management guide called GEM (Glycemic Excursion Minimization) alongside continuous glucose monitoring (CGM) and an activity monitor (FitBit) and the effect this can…
- Trial name
- IMPEDE (NCT05580978)
- Testing
- GEM, Routine Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Colorado, Denver
HIV/AIDS, Tuberculosis
Targeted Universal TB Testing With Simultaneous TPT Prescribing Among People Living With HIV in South Africa
Background: In 2023, the South African Department of Health introduced targeted universal TB testing (TUTT) at antiretroviral therapy (ART) initiation (irrespective of the presence of TB symptoms).
- Trial name
- TUTT-PT (NCT06739915)
- Testing
- TUTT-PT Intervention
- Where
- South Africa
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Xerosis Cutis
Skin Health and Effectiveness of Standardized Skin Care Regimens in Nursing Home Residents
Residents of institutional long-term care facilities are at high risk for developing skin and tissue diseases, e.g. xerosis cutis (including pruritus), infections (e.g., tinea pedis, candidiasis), chronic wounds or neoplastic…
- Trial name
- NCT02216526
- Testing
- Cetaphil® Restoraderm, Excipial
- Where
- Germany
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Suicidal Ideation, Suicidal Behaviors
Pilot RCT of a Video-based Intervention for Suicide Prevention
The investigators will develop a brief video-based intervention for suicide prevention, called LifePlans. LifePlans will be tested in a pilot randomized controlled trial (n = 40) to examine its feasibility and acceptability.
- Conditions
- Suicidal Ideation, Suicidal Behaviors, Suicide
- Trial name
- NCT05127330
- Testing
- LifePlans, Treatment as Usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Butler Hospital
Influenza
Feasibility of Cocooning Immunization Strategy With Influenza Vaccine
Influenza causes epidemics of respiratory infection in young children each winter. Young children, particularly those under 6 months of age are most vulnerable to suffering from complications secondary to influenza infection.
- Trial name
- Piiitch (NCT00570037)
- Testing
- Trivalent inactivated influenza vaccine
- Where
- 2 sites in United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Duke University
Stress, Psychological, Caregiver Burden
Wellness Coaching for Caregivers of Thoracic Transplant Candidates
Researchers are studying the effects of a health coaching intervention on the stress and burden of caregivers of patients awaiting heart or lung transplant.
- Trial name
- NCT04245228
- Testing
- Wellness Coach
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spina Bifida, Latex Allergy
Yulex Glove Prospective Study in Spina Bifida
This study is to evaluate the safety of Yulex gloves when used by individuals who have documented allergy to natural rubber latex from Hevea brasiliensis.
- Trial name
- NCT01133288
- Testing
- Yulex gloves
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Posttraumatic Stress Disorder
Improving Veteran Adherence to Treatment for PTSD Through Partnering With Families
Evidence-based psychotherapies (EBP) for PTSD, such as Prolonged Exposure (PE), result in clinically significant symptom relief for many.
- Trial name
- NCT03256227
- Testing
- Family Supported Prolonged Exposure, Standard Prolonged Exposure
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Osteoporosis
36-month Special Drug Use Surveillance on Frequency of Bone Fractures With Sodium Risedronate 75 mg Tablets
The purpose of this survey is to evaluate the effectiveness (endpoints: frequency of bone fractures, percent change in bone density, etc.) and safety of administration of sodium risedronate tablets 75 mg for 36 months in…
- Trial name
- NCT02106442
- Testing
- Sodium risedronate
- Where
- 2 sites in Japan
- Volunteers
- 579 people
- Sponsor
- Takeda
Bipolar Disorder
Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
In this study, patients with bipolar disorder who do not take their medications as prescribed will receive specialized education and therapy treatment to determine whether the specialized treatment is effective in helping…
- Trial name
- NCT00763919
- Testing
- Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Case Western Reserve University
Peer Influence, Medication Adherence
Effect of Peer Support Intervention on Medication Adherence, Self-care and Knowledge Among Patients With Diabetes
The goal of this interventional study is to learn about the effect of a peer support group intervention on adherence, self-care practice, and knowledge among diabetic patients on follow-up care.
- Conditions
- Peer Influence, Medication Adherence, Self Care
- Trial name
- DM (NCT07145983)
- Testing
- Structured Diabetes Education on medication Adherence and self care
- Where
- Ethiopia
- Volunteers
- 120 people
- Sponsor
- Addis Ababa University
Opioid Use Disorder
A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail
The purpose of this study is to determine which of three approaches started in jail is more effective in treating opioid use disorder: (1) methadone treatment without counseling (termed interim methadone) coupled with case…
- Trial name
- SOMATICS FRI (NCT02334215)
- Testing
- Methadone, Patient Navigation, Enhanced Treatment as Usual (ETAU)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Friends Research Institute, Inc.
Perineal Injury
Designed Protocol of Care for Postpartum Perineal Trauma
the study is intended to test the effect of designed protocol of care that include perineal ice-gel pad application, performance of pelvic floor exercises (Kegel exercises) and perineal warm compresses application on the outcomes…
- Trial name
- NCT05268276
- Testing
- 1-perineal ice-gel pad application, 2-performance of pelvic floor exercises (Kegel exercises), 3- perineal warm compresses application
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Asmaa Abdallah Ahmed Hussein