Clinical trials: Routine care
Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer
Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
- Trial name
- NCT07092111
- Testing
- Auricular acupuncture treatment
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Metabolic Dysfunction-Associated Steatotic Liver Disease
Clinical Profile of Patients With MASLD in Kazakhstan and Clinical Effectiveness of Ursosan in Almaty
This study will look at the health characteristics of adults with metabolic dysfunction-associated steatotic liver disease (MASLD) in Kazakhstan.
- Trial name
- NCT07889999
- Where
- 7 sites in Kazakhstan
- Volunteers
- 420 people
- Sponsor
- Kazakh Association of Internal Medicine Specialists
Down Syndrome
Promoting Health Through Parent Empowerment and the Activation of Routines (PrO-PEAR)
This study will examine the feasibility of the Promoting Health through Parent Empowerment and the Activation of Routines (Pro-PEAR) intervention using a open case-series for intervention optimization followed by a pilot RCT in…
- Trial name
- Pro-PEAR (NCT05020366)
- Testing
- Promoting Health through Parent Empowerment and the Activation of Routines, Enhanced Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Normal Labor
Generative AI-Powered Intrapartum Clinical Decision Support Among Healthcare Providers
Pregnancy and childbirth are uniquely important events in women's lives because they are accompanied by major physical, emotional, and psychological changes.
- Trial name
- NCT07720531
- Testing
- Generative AI-Powered Intrapartum Chatbot
- Where
- Egypt
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Large for Gestational Age Baby, Macrosomia, Fetal
A First Trimester Prediction Model for Large for Gestational Age Infants: a Preliminary Study
Large for gestational age infants (LGA) have increased risks of adverse short-term perinatal outcomes. This study aims to develop a multivariable prediction model for the risk of giving birth to a LGA baby, by using biochemical…
- Trial name
- PreMoLGA (NCT04838431)
- Testing
- Blood sample and ultrasound at first trimester
- Where
- Italy
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Cataract, Astigmatism
Conventional Surgery vs. Verion/VerifEye
Nowadays cataract patient's expectations are closer to those of refractive surgery patients. Patients want to be spectacle independent.
- Trial name
- NCT02513745
- Testing
- Conventional, Refractive Cataract Suite (Verion + ORA)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Preoperative Anxiety, Fear
Virtual Reality for Pediatric Perioperative Preparation
This pilot randomized controlled trial will evaluate whether a virtual reality (VR) preparation program can improve the perioperative experience of children aged 3 to 12 years undergoing elective surgery.
- Conditions
- Preoperative Anxiety, Fear, Pediatric Surgery, Preoperative Care
- Trial name
- NCT07650695
- Testing
- NixiKit Virtual Reality Preparation, Standard Nursing Preoperative Preparation
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Fundación de investigación HM
Colon Cancer, Lung Cancer
Effectiveness of Electronic Health Record-Based Interventions for Improving Follow-Up in Primary Care
Diagnostic delays in ambulatory care are often due to breakdowns of related care processes. Electronic systems can improve follow-up and reduce delays by detecting missed appointments or incomplete procedures so that patients are…
- Conditions
- Colon Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT01346839
- Testing
- Contact Intervention
- Where
- 2 sites in United States
- Volunteers
- 1,256 people
- Sponsor
- Baylor College of Medicine
HIV/AIDS
INcentives and ReMINDers to Improve Long-term Medication Adherence
The study will test the feasibility and acceptability of using text messages and behavioral economics-based incentives to support anchoring Anti-Retroviral Therapy (ART) adherence to an existing routine in order to improve…
- Trial name
- INMIND (NCT05131165)
- Testing
- Daily Text Messages, Incentivization based on timely ART adherence
- Where
- Uganda
- Volunteers
- 166 people
- Sponsor
- RAND
Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Diagnostic and Clinical Management of Non-Obstructive Myocardial Ischemia in Patients With Long Covid-19 Syndrome and New Onset Chest Pain
Long Covid-19 INOCA is an investigator-initiated, prospective, randomized, sham-controlled, single center study. Its objective is to investigate the benefits of tailored medical therapy according to the results of the coronary…
- Conditions
- Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Long COVID-19 Syndrome
- Trial name
- NCT07559994
- Testing
- Coronary functional test
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Acute Ischemic Stroke (AIS), Pediatric Stroke
Prospective Registry of Acute Ischemic Stroke in Children Under 18 Years Old in China
This observational study aims to investigate the real-world effectiveness and safety of different treatment strategies for acute ischemic stroke (AIS) in Chinese children under 18 years of age.
- Trial name
- NCT07550257
- Testing
- Standard Clinical Management
- Volunteers
- 1,000 people
- Sponsor
- Gansu Provincial Maternal and Child Health Care Hospital
Single Ventricle Defect
Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction
This study seeks to determine cerebral blood flow changes in single ventricle patients during staged surgical reconstruction as compared with normal children.
- Trial name
- CBF (NCT02135081)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital of Philadelphia
Uropathy, Kidney Transplantation
Feasibility of Magnetic-end Double-J Ureteral Stent Use in Children
Double-J ureteral stent (DJUS) is one of the most common devices used in urology. Ureteral stenting has a wide spectrum of indications that can be summarized in two words: obstruction and leakage.
- Trial name
- EFUJA (NCT04384939)
- Testing
- magnetic-end Double-J ureteral stent
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infections, Hiv
Diagnosis of HIV and Early Antiretroviral Therapy Initiation Among HIV-1 Infected Infants
The purpose of the study is to test the effect of the Alere™ q HIV-1/2 Detect (diagnostic assay) on uptake of HIV testing among HIV-exposed infants and young children, and health outcomes for HIV-infected infants and young…
- Trial name
- CDC Detect (NCT03133728)
- Testing
- Alere Q Testing
- Where
- 6 sites in Zambia
- Volunteers
- 1,682 people
- Sponsor
- University of Alabama at Birmingham
Normal Vaginal Delivery, Perineal Episiotomy
Effect of Perineal Cryotherapy on Episiotomy
The present study aims to evaluate the effect of perineal cryotherapy on episiotomy- associated pain among postpartum women. The study hypothesis: Post-partum women who apply perineal cryotherapy have lower level of episiotomy…
- Trial name
- NCT06921200
- Testing
- Cryotherapy
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Acute Ischemic Stroke and Transient Ischemic Attacks
Computer Scan Based Analysing System on Improving Stroke Management Quality Evaluation
Study is designed for two parts, a perspective, multi-center, historial control study and a randomized controlled study of acute ischemic stroke patients.
- Trial name
- CASE (NCT03684629)
- Testing
- the response of KPI and corresponding suggestion
- Where
- China
- Volunteers
- 16,570 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Type 2 Diabetes Mellitus, Primary Prevention
The Impact of a Diabetes Risk Prediction Model in Primary Care.
Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient's behavior, perceived risk of persons, shared-decision making and particularly on patient´s health.
- Trial name
- NCT03234322
- Testing
- external validated risk prediction model
- Where
- Germany
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Mothers
Peer Interaction of Primiparas Sharing a Room With Multiparas With Successful Breastfeeding Experience
The World Health Organization (WHO) states that peer support breastfeeding education programs are effective interventions for improving breastfeeding outcomes.
- Trial name
- NCT06277856
- Testing
- Peer interaction/control
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ege University
Advanced Solid Tumor
Implementation of Liquid Biopsies During Routine Clinical Care in Patients With Advanced Malignancies (LIQPLAT)
The goal of this study is to assess the implementation and feasibility of ctDNA measurements from blood samples obtained during routine clinical care of cancer patients in the University Hospital Basel.
- Trial name
- LIQPLAT (NCT06367751)
- Testing
- ctDNA measurement
- Where
- Switzerland
- Volunteers
- 159 people
- Sponsor
- University Hospital, Basel, Switzerland
Alcohol Use Disorder, Addiction
Portrayal of Hospital Alcohol Detoxification in France
Even if hospital alcohol detoxifications are frequent in France, their caracteristicscharacteristics remain unknown. The investigators aim to describe the clinical and paraclinical caracteristicscharacteristics of their patients…
- Conditions
- Alcohol Use Disorder, Addiction, Alcohol Withdrawal Syndrome
- Trial name
- Alcostop (NCT04973202)
- Testing
- Stay for alcohol detoxification
- Where
- France
- Volunteers
- 50,000 people
- Sponsor
- University Hospital, Montpellier
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