Clinical trials: Routine care
Smoking Addiction
Evaluation of the Effectiveness of Routine Nurse Education in Prescribing Nicotine Replacement Therapy for Hospitalized Smokers in a University Hospital
The goal of this study is to determine whether training nurses to prescribe nicotine replacement therapy (NRT) can increase the proportion of smoking cessation at one month after hospital discharge among active smokers (daily or…
- Trial name
- NICOTINURSE (NCT06789536)
- Testing
- training nurses to prescribe nicotine substitutes, to adapt doses and to transmit to the outpatient physician and/or nurse nurse to facilitate the continuation of treatment
- Where
- 4 sites in France
- Volunteers
- 442 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8
Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial
This phase II trial tests the impact of biomarkers in predicting initial treatment (first-line) PD1 or PD-L1 (PD[L]-1)-based immunotherapy response and in selecting second-line treatment in patients with stage IIIB-IV non-small…
- Conditions
- Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
- Trial name
- NCT07288034
- Testing
- Adagrasib, Anti-PD-L1 Monoclonal Antibody, Anti-PD1 Monoclonal Antibody
- Where
- 13 sites in United States
- Volunteers
- 535 people
- Sponsor
- City of Hope Medical Center
Surgery
The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery
The study is enrolling adults who are scheduled for either inpatient or outpatient elective surgical procedures at The University of Chicago.
- Trial name
- NCT03729180
- Testing
- Routine Elective Surgery- In patient or out patient elective surgery, Blood test for genetic testing, Drug-genetic Profile
- Where
- United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Heart Failure
Effect of Intra-session Exercise Modes Sequence on Ventricular Function in Patients With Chronic Heart Failure
The aim of this study was to investigate the effect of intra-session exercise modes sequence on ventricular function in patients with chronic heart failure.
- Trial name
- NCT06626542
- Testing
- resistance and aerobic training exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Bipolar Disorder
Family Focused Therapy for Teens at Risk for Bipolar Disorder
The present study aims to examine the effects of a 4 month, family focused therapy (FFT) intervention on the 1 year course of mood symptoms in offspring of parents with bipolar disorder (BD).
- Trial name
- NCT02355366
- Testing
- Family-Focused Therapy, Brief Educational Treatment
- Where
- Canada
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Postpartum Depression, Emotional Regulation
Prenatal Affective Cognitive Training to Reduce the Risk of Postpartum Depression (PACT)
Many pregnant women face the risk of experiencing depression after giving birth, especially if they've previously dealt with depression.
- Conditions
- Postpartum Depression, Emotional Regulation, Cognitive Function 1, Social, Pregnancy Related
- Trial name
- PACT (NCT06046456)
- Testing
- Prenatal Affective CogntiiveTraining
- Where
- Denmark
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Solid Tumors, Hematologic Cancers
Genomic Profiling in Cancer Patients
The purpose of this study is to determine whether certain genes in cancer may be abnormal. When a gene is abnormal this is called a mutation.
- Trial name
- NCT01775072
- Testing
- molecular profiling of tumors, Clinical Germline Analysis
- Where
- 18 sites in United States
- Volunteers
- 200 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fetal Growth Retardation
Management of Fetal Growth Restriction at Term: Angiogenic Factors Versus Feto-placental Doppler
Open randomized non-inferiority controlled trial to examine the use of angiogenic factors (instead of feto-placental Doppler) for fetal growth restriction at term to reduce the rate of labor inductions, without worsening…
- Trial name
- GRAFD (NCT04502823)
- Testing
- Management based on sFlt-1/PlGF values
- Where
- 20 sites in Spain
- Volunteers
- 1,088 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Asthma
Improving Asthma Care Through Parental Empowerment
The overall aim of this study will be to perform a prospective randomized clinical trial of an enhanced version of the IMPACT DC intervention involving short-term case management to facilitate PCP follow-up appointments and to…
- Trial name
- PEPAC (NCT00832923)
- Testing
- PEPAC
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's National Research Institute
Osteoarthritis (OA) of the Knee
Photographic Evidence on Total Knee Arthroplasty Outcomes
Historically, total knee arthroplasty (TKA) has been performed to restore knee range of motion and relieve pain, with postoperative rehabilitation focused on helping patients regain mobility and function.
- Trial name
- NCT07223359
- Testing
- Photographic Evidence of Postoperative Knee Range of Motion, Standard Postoperative Care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Loyola University
Infant Development, Cerebral Palsy
Cerebrolysin and Neurodevelopment in Preterm Infants
The overall aim of the study is to assess the effect of Cerebrolysin on physical and mental development of preterm infants by Denver Scale II at different ages of 5, 7 and 12 months
- Conditions
- Infant Development, Cerebral Palsy, Preterm Infant
- Trial name
- NCT03506841
- Testing
- Cerebrolysin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Growth Retardation, Malnutrition
Nutrition Education Package for Infants and Young Child Feeding and Health in Rural Tanzania
Building on the success of community-based peer education and counselling in breastfeeding, it is possible to address young child feeding and health practices in the surveyed district.
- Trial name
- NECTAc (NCT02249754)
- Testing
- Nutrition education, Routine health education
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sokoine University of Agriculture
Fractures, Bone, Dementia
Function Focused Care: Fracture Care at Home
This pilot study will evaluate the feasibility of implementing an intervention in the home setting that is specifically designed to coach and mentor caregivers as they assist individuals with Alzheimer's disease and related…
- Trial name
- NCT03147222
- Testing
- Fracture Care at Home
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Urinary Calculus
The Effect of Transcutaneous Electrical Nerve Stimulation in Patients After Retrograde Intrarenal Surgery
This study is designed to evaluate the effects of Transcutaneous Electrical Nerve Stimulation (TENS) on pain, nausea, vomiting, and quality of recovery in patients undergoing Retrograde Intrarenal Surgery (RIRS).
- Trial name
- RIRS TENS (NCT07405502)
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bozok University
Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers
Glove Compression for Chemotherapy-Induced Neuropathy
This study investigates whether wearing tight-fitting surgical gloves on the non-dominant hand could help prevent chemotherapy-induced peripheral neuropathy (CIPN) in women with gynecologic cancers treated with paclitaxel.
- Conditions
- Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers, Ovarian Cancer (OvCa), Endometrial Cancer
- Trial name
- NEURO-GLOVE (NCT07105553)
- Testing
- Surgical Glove Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Chronic Obstructive Pulmonary Disease
Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo
Chronic Obstructive Pulmonary Disease is a leading cause of global morbidity and mortality, especially in low- and middle-income countries. Exacerbations accelerate disease progression and increase the risk of death.
- Trial name
- iCHOROS (NCT07069829)
- Where
- 36 sites in Argentina, Colombia and 10 more
- Volunteers
- 1,400 people
- Sponsor
- AstraZeneca
Older Adult, Motivational Interviewing
The Effect of Nurse-led Motivational Interviewing Based on the Trans-theoretical Model
Older adults constitute the age group that leads the most sedentary life in society and is mostly affected by physical inactivity.
- Conditions
- Older Adult, Motivational Interviewing, Physical Activity, Nursing Caries
- Trial name
- NCT04128553
- Testing
- Intervention motivational interview group
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Gazi University
Knee Osteoarthritis, Arthroplasty, Replacement, Knee
Implementation of Indication Criteria for Total Knee Replacement in Osteoarthritis (Value-based TKR)
The aim of this trial is to investigate the effect of a medical decision aid (EKIT-Tool) on decision quality for knee arthroplasty.
- Trial name
- NCT04837053
- Testing
- Digital decision aid for physicians and patients, Routine care
- Where
- Germany
- Volunteers
- 1,092 people
- Sponsor
- Technische Universität Dresden
Breast Cancers
Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs
The goal of this study was to explore the safety and efficacy of hyperbaric oxygen in the treatment of peripheral neuropathy due to paclitaxel analogues
- Trial name
- NCT06819501
- Testing
- hyperbaric oxygenation treatment, routine care
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Guangdong Provincial People's Hospital
Migraine
Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study
Preventive pharmacologic therapies for migraine aim to reduce attack frequency and duration and improve quality of life; however, their use, overall benefit and adherence are often limited.
- Trial name
- NCT07487701
- Testing
- Nerivio REN device
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Theranica
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