Clinical trials: Routine care, completed
Type 1 Diabetes
Evaluation of Glycemic Control in Adults With Type 1 Diabetes When Switching to Insulin Degludec
Retrospective multicenter study analyzing data gathered from medical records and diabetes management platforms to assess the effect of using Insulin Degludec (Tresiba®) on measures of diabetes control.
- Trial name
- GLADE (NCT05434559)
- Testing
- Insulin Degludec
- Where
- 2 sites in Belgium
- Volunteers
- 475 people
- Sponsor
- prof dr Pieter Gillard
Patient Discharge
The Impact of Just-in-time Information on Neonatal Intensive Care Unit (NICU) Discharges
We, the investigators, will provide "Just-in-Time" information, physician educational material, to primary care pediatricians of Neonatal Intensive Care Unit (NICU) graduates at the time of NICU discharge.
- Trial name
- NCT01091688
- Testing
- Just-in-Time information
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Virginia Moyer
Type 1 Diabetes
Description of Patients With Type 1 Diabetes Treated With Teplizumab
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the destruction of pancreatic β cells. T1D pathogenesis progresses through several stages: Stage 1 T1D includes the presence of β cell autoimmunity and thus…
- Trial name
- TEPLI-REAL (NCT06892002)
- Testing
- Teplizumab
- Where
- 27 sites in United States, Israel
- Volunteers
- 110 people
- Sponsor
- Sanofi
Childbirth Problems, Birth; Delayed
Birth Environment and Childbirth-stress, Control & Outcome
This research improves the correlation between birth control and birth outcomes by understanding the childbirth environment and birth stress. A Quasi Experiment research .
- Trial name
- NCT04888013
- Testing
- Positive Birth Environment
- Where
- Taiwan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Atrial Fibrillation and Other Dysrhythmias | Patient
French Database of Left Atrial Appendage Closure
Patients with atrial fibrillation are exposed to a high risk of thrombus in the left atrium that can induce cerebral vascular events or systemic embolisms.
- Trial name
- FLAAC (NCT02252861)
- Testing
- Percutaneous Left Atrial Appendage Closure in routine care
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Henri Mondor University Hospital
Neuromuscular Adaptations
Specific Neurotechnical Strength Training (NeuroTraining)
This study aims to apply a novel study methodology using high density electromyography (HDEMG) to know what are the mechanisms underlying the structural and functional changes obtained by two different training methods, commonly…
- Trial name
- NCT04286022
- Testing
- Speed Loss 20% Strength Training, Reduced Rest Time Strength Training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Atrial Fibrillation, Fibrosis Myocardial
Atrial Fibrillation Driver Study
Atrial Fibrillation (AF) is an abnormal rhythm of the heart which is increasingly common and can be associated with serious consequences.
- Trial name
- NCT05743829
- Testing
- Tissue excision as part of routine clinical care
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Methadone, Drug Use Disorders
Comparison of Two Counseling Induction Strategies
New admissions (n = 120) to the Addiction Treatment Services (ATS) will be stabilized on methadone and randomly assigned to one of two induction conditions: 1) routine stepped care, or 2) low threshold stepped care.
- Trial name
- NCT01141920
- Testing
- low threshold care, stepped-based care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Johns Hopkins University
Implantable Cardioverter-defibrillators (ICDs)
Nursing Intervention Guided by an ICD Nursing Guideline
This study aimed to evaluate evidence-based nursing intervention guided by an ICD nursing guideline on self-efficacy, device acceptance, satisfaction with nursing care, and outcome expectations among ICD candidates during the…
- Trial name
- NCT07449559
- Testing
- nursing care with an evidence-based ICD nursing guideline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Gastro-esophageal Reflux Disease
Validation of a Non-invasive In-vitro Diagnostic Test (Peptest) Against Other Diagnostic Methods for GERD
The primary objective of this clinical study is to determine whether Peptest (Human Pepsin lateral flow in vitro diagnostic medical device) is equivalent to other GERD diagnostic methods commonly applied in clinical practice by…
- Trial name
- PEPTESTCN (NCT02456779)
- Testing
- in vitro diagnostic test (Peptest), Questionnaire
- Where
- 9 sites in China
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- MAAB (Shanghai) Medical Device Limited
Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation
Machine Learning Prediction of Mortality After Prone Positioning in ARDS
Acute respiratory distress syndrome (ARDS) is a life-threatening condition with high mortality. Prone position ventilation (PPV) is an evidence-based therapy that improves oxygenation and survival in patients with moderate to…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation, Machine Learning, ICU
- Trial name
- NCT07445061
- Testing
- Prone Position Ventilation
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Shanghai Zhongshan Hospital
Long COVID
Cognitive Impairment and Return to Work in Long COVID
This retrospective, single-center observational study investigates the relationship between cognitive performance and return to work in patients with Long COVID.
- Trial name
- REWORK-COV (NCT07881029)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hopitaux de Saint-Maurice
Reflexology
The Effect of Reflexology on Labor
Aims and Objectives: The purpose of this study was to determine the effect of reflexology, one of the non-pharmacological methods used in the management of labor pain, on anxiety, labor duration, labor pain, and labor…
- Trial name
- NCT03877302
- Testing
- reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Alzheimer Disease, Dementia
Efficacy of Gamification in Enhancing User Engagement
As part of Phase II of the NIH SBIR grant, the study will conduct a randomized controlled clinical trial in which the MapHabit system's gamification is investigated to determine whether the assistive technology facilitates user…
- Conditions
- Alzheimer Disease, Dementia, Gamification, Assistive Technology
- Trial name
- NCT05422339
- Testing
- The MapHabit system (MHS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MapHabit, Inc.
Hypertension, Diabetes Mellitus, Type 2
Proteus Discover in Subjects With Uncontrolled Hypertension and Type 2 Diabetes
The purpose of this study was to evaluate the efficacy of a new digital health offering, Proteus Discover to lower blood pressure and glycated hemoglobin in patients with uncontrolled hypertension and type 2 diabetes.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Hypercholesterolemia
- Trial name
- NCT02827630
- Testing
- Proteus Discover, Usual Care
- Volunteers
- 118 people
- Sponsor
- Proteus Digital Health, Inc.
Total Knee Arthroplasty, Patient Education
The Effect of the Educational Plan Prepared According to the Health Literacy Levels of Patients
The reasons such as the advanced age of most patients with Total Knee Arthroplasty (TKA), the presence of concomitant diseases, and bilateral prostheses cause a decrease in the quality of life by negatively affecting the healing…
- Trial name
- NCT05088551
- Testing
- Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bozok University
Type 2 Diabetes Mellitus, Cardiovascular Autonomic Dysfunction
Nurse-Led Self-Management and Breathing Intervention in Type 2 Diabetes
Brief Summary This study evaluated the effect of a structured nurse-led home-based self-management and paced-breathing intervention on cardiovascular autonomic function and blood pressure among adults with type 2 diabetes…
- Trial name
- NCT07847177
- Testing
- Structured Nurse-Led Home-Based Self-Management and Paced-Breathing Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Aziza Ibrahim Mohamed
Insulin Dependent Diabetes Mellitus
Strategies to Minimize the Risk for Insulin Induced Hypertrophy and Its Related Consequences
Hypertrophy caused by insulin has effects that extend beyond just aesthetic concerns. Innovative methods have shown potential in decreasing the chances of hypertrophy and its related issues, including the development of detailed…
- Trial name
- NCT07375875
- Testing
- Group(1) Insulin site injection map
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Mansoura University
Critical Illness
Predicting Early Circulatory Deterioration After Short-Acting Beta-Blocker Treatment in Intensive Care Patients
This retrospective observational study used existing intensive care records to examine whether heart rate and blood pressure measured before short-acting beta-blocker treatment could help predict early signs of worsening…
- Trial name
- NCT07846995
- Testing
- Esmolol, Landiolol
- Where
- China
- Volunteers
- 2,541 people
- Sponsor
- Shanghai Zhongshan Hospital
Alcoholism, Substance-related Disorders
Treatment Engagement With Technology-assisted Treatment
This research is being done to study whether using an Internet-based program, called the Therapeutic Education System (TES), would be helpful for the treatment of substance use and other psychiatric problems.
- Conditions
- Alcoholism, Substance-related Disorders, Mentally Ill Chemical Abuse, Educational Technology
- Trial name
- TETAT (NCT02674477)
- Testing
- Therapeutic Education System (TES), Treatment as Usual (TAU)
- Volunteers
- 95 people
- Sponsor
- Johns Hopkins University
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