Clinical trials: Routine care
Hand Osteoarthritis
An Integrated Self Management Programme to Improve Outcomes in Patients With Hand Osteoarthritis
The goal of this trial is to evaluate the efficacy of an integrated self-management programme in improving clinical outcomes in patients with hand osteoarthritis (OA).
- Trial name
- OASIS-H (NCT06264908)
- Testing
- Integrated self-management programme
- Volunteers
- 90 people
- Sponsor
- Dr Iris Tang Yan Ki
Thoracic Diseases
Effect of Manual Chest Wall Vibration on Respiratory Function and Chest Tube Duration After Thoracic Surgery
This study was conducted to determine the effects of a manual vibration technique applied to the chest wall on the duration of chest tube placement, secretion clearance, and hemodynamic parameters in patients with chest tubes.
- Trial name
- NCT07549555
- Testing
- Chest Wall Oscillation, Conventional Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Degenerative Disc Disease Lumbar, Spinal Stenosis
Multimodal Analgesia Versus Routine Care Pain Management
Most patients undergoing surgery experience significant post-operative pain. Inadequate peri-operative pain management may decrease post-operative mobilization and increase length of hospitalization.
- Conditions
- Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- MMA (NCT01861743)
- Testing
- Multimodal Analgesia, Patient controlled analgesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Malaria Infection, Pregnancy
Diagnostic Access to Self-Care and Health Services in Low and Middle Income Countries (DASH) - Phase II
Our primary goal is to determine if on-demand, home-based rapid testing, or rapid testing done by a community health worker (CHW) results in people testing for diseases more frequently and getting care more quickly.
- Conditions
- Malaria Infection, Pregnancy, HIV, Diabetes
- Trial name
- DASH (NCT06588790)
- Testing
- Home-based rapid testing, Community health worker rapid testing
- Where
- 3 sites in Kenya, South Africa and 1 more
- Volunteers
- 2,250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Burn, Surgery
A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting
The purpose of this study if to evaluate the effectiveness of prophylactic antibiotics given during surgery in reducing the concentration of bacteria in a burn wound after surgery.
- Conditions
- Burn, Surgery, Infection Wound
- Trial name
- NCT04516148
- Testing
- Cefazolin, Clindamycin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medstar Health Research Institute
Pulmonary Artery Pressure, Thalassemia
Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia
The goal of this clinical trial is to learn whether L-glutamine can help lower pulmonary artery pressure in adults with non-transfusion-dependent thalassemia (NTDT).
- Conditions
- Pulmonary Artery Pressure, Thalassemia, Non-transfusion Dependent Thalassemia
- Trial name
- NCT07210450
- Testing
- L-glutamine
- Where
- Iran
- Volunteers
- 8 people
- Sponsor
- Mazandaran University of Medical Sciences
Cesarean Section Complications, Opioid Use
TENS and Opioid Use After Cesarean Delivery
We propose to explore the effects of Transcutaneous Electrical Nerve Stimulation (TENS) therapy in the pain management of postpartum women. A.
- Trial name
- NCT03843788
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Labor Pain, Duration of Labor
Effect of Hot Pack on Labor Pain, Duration of Labor, and Satisfaction of Primigravidae Women in Saudi Arabia
The study aimed at determining the effect of hot pack on labor pain reduction and the duration of labor in comparison with routine care.
- Conditions
- Labor Pain, Duration of Labor, Satisfaction
- Trial name
- NCT04177888
- Testing
- Hot Pack
- Where
- Saudi Arabia
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- King Saud University
Arteriovenous Graft Thrombosis, End Stage Renal Disease on Dialysis
Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis
Patients with end-stage renal disease (ESRD) often require arteriovenous grafts (AVG) for hemodialysis. AVG thrombosis is a common complication, usually managed by percutaneous transluminal angioplasty (PTA) to restore blood…
- Trial name
- NCT07613632
- Testing
- Electrical Impedance Tomography (EIT) Monitoring
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Intracerebral Hemorrhage, Subarachnoid Hemorrhage
Al Prediction of Sarcopenia Risk in Neurocritical ICU Patients
This prospective observational study aims to evaluate sarcopenia in intensive care patients with intracranial pathologies using ultrasound and to compare the predictive performance of different artificial intelligence models.
- Conditions
- Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, Epidural Hematoma
- Trial name
- NCT07712198
- Testing
- Prospective Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Infertility of Uterine Origin
Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)
Our study will explore the feasibility of initiating a deceased donor uterine transplant program in addition to the existing living donor IRB at BWH.
- Trial name
- NCT04026893
- Testing
- Uterine Transplant from Deceased Donor
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cesarean Section; Dehiscence, Postoperative Pain
The Effect of Music Postoperative Period
This randomized controlled trial aimed to evaluate the effects of music listening on anxiety and pain among women following cesarean delivery. A total of 110 women who had undergone cesarean section were included.
- Trial name
- EMPP (NCT07164521)
- Testing
- Music Listening (Relaxing Classical Music)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cancer
Symptom Screening With Targeted Early Palliative Care (STEP) Versus Usual Care for Patients With Advanced Cancer
Palliative care is defined as multidisciplinary care that increases quality of life (QOL) for patients with a life-threatening illness.
- Trial name
- STEP (NCT03987906)
- Testing
- Symptom screening with Targeted Early Palliative Care (STEP)
- Where
- 2 sites in Canada
- Volunteers
- 69 people
- Sponsor
- University Health Network, Toronto
Obesity / Overweight
Effects of Tirzepatide on Gut Microbiota and Gastrointestinal Function After Drug Withdrawal in Obese Patients
This is an observational cohort study. The primary objective is to analyze the dynamic changes in gut microbiota and metabolic profiles in obese patients treated with Tirzepatide.
- Trial name
- NCT07847515
- Testing
- Tirzepatide
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypertension, Cardio Vascular Disease
Assessing the Feasibility of Multimedia Interventions to Reduce Blood Pressure in Marginalized Hypertensive Communities of Karachi, Pakistan
This study utilizes the I-Change Model to empower individuals in literacy-limited settings, where the majority of the population is illiterate.
- Conditions
- Hypertension, Cardio Vascular Disease, Educational Intervention, Self Care
- Trial name
- NCT07131176
- Testing
- Behavior Change through Education intervention
- Volunteers
- 150 people
- Sponsor
- SINA Health Education and Welfare Trust
Acute Coronary Syndrome (ACS)
Self-Management Support for Acute Coronary Syndrome Patients After Hospital Discharge
This randomized controlled trial evaluates a "Hospital-to-Home" self-management support model for Acute Coronary Syndrome (ACS) patients, which is based on the integrated COM-B and HAPA theories.
- Trial name
- ACS (NCT07799376)
- Testing
- COM-B and HAPA-based Self-management Support Program, Routine Health Education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cardiovascular Diseases
Adequacy of the Indication of Lipid Lowering Treatment in Primary Prevention
OBJECTIVE: To evaluate the impact of an intervention addressed to health professionals to improve the adequacy of lipid-lowering prescription in primary prevention of cardiovascular disease and reducing expenditure in this…
- Trial name
- NCT01997671
- Testing
- Information Support System
- Where
- Spain
- Volunteers
- 60,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Chronic Obstructive Pulmonary Disease (COPD)
Reducing Sedentary Behavior in Patients with Severe COPD: a Feasibility Study on Nurse-Led Motivational Intervention
This feasibility study aims to assess the practicality and acceptability of a nurse-led motivational interview intervention designed to reduce sedentary behavior in patients with severe Chronic Obstructive Pulmonary Disease…
- Trial name
- NCT06882863
- Testing
- Motivational interviewing
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Zealand University Hospital
Congenital Diaphragmatic Hernia
Safety and Efficacy of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Congenital Diaphragmatic Hernia (CDH)
The purpose of the study is to determine if babies with left or right-sided CDH that undergo the FETO procedure survive more often and have fewer long-term complications than babies that have similar left or right-sided CDH that…
- Trial name
- NCT07577414
- Testing
- FETO with Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dr Erin Perrone
Obesity, Childhood
GOOD-DAY Trial in Paediatric Obesity
Alongside efforts in public health and policy to reverse the childhood obesity epidemic, medical providers seek to play effective roles in prevention and treatment.
- Trial name
- GOOD-DAY (NCT03154255)
- Testing
- Mediterranean-Style Diet Educational Training
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
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