Clinical trials: Routine care
Adenoid Cystic Carcinoma of the Salivary Gland, Adenoid Cystic Carcinoma of the Head and Neck
A Multi-omics Approach to Disclose Progression and Underlying Biology of Head and Neck Adenoid Cystic Carcinoma
The goal of this observational study is to better understand why some people with metastatic adenoid cystic carcinoma (ACC) of the head and neck have slow-growing disease while others have faster-growing or more aggressive…
- Trial name
- MAPPING-ACC (NCT07507578)
- Testing
- Standard of Care (Investigator Choice)
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Catheter-related Bloodstream Infection
Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)
We proposed to perform a prospective randomized controlled trial to study the effect of the use of a commercially-available chlorhexidine-impregnated sponge (Biopatch) as part of central venous catheter care on catheter-related…
- Trial name
- NCT00548132
- Testing
- Chlorhexidine-impregnated foam dressing
- Where
- United States
- Volunteers
- 1,088 people
- Sponsor
- Washington University School of Medicine
Pediatric Functional Dyspepsia
Parent-administered Pediatric Tuina Versus Routine Care for Pediatric Functional Dyspepsia
Title: Parent-administered pediatric tuina with routine care versus routine care alone for pediatric functional dyspepsia: a pilot randomized controlled trial Background: Pediatric functional dyspepsia (PFD) is a common…
- Trial name
- NCT07369687
- Testing
- parent-administered pediatric tuina
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder, Psychological Distress
Feasibility of a Culturally Adapted Nurse-Led COPE Intervention for Caregivers of Children With Autism Spectrum Disorder
This study aims to evaluate the feasibility of a culturally adapted, nurse-led Creating Opportunities for Parent Empowerment (COPE) intervention to improve the psychological wellbeing of primary caregivers of children with Autism…
- Conditions
- Autism Spectrum Disorder, Psychological Distress, Depression, Anxiety
- Trial name
- COPE-ASD (NCT07722949)
- Testing
- Culturally Adapted Nurse-Led COPE Intervention, Routine Hospital Care
- Where
- Pakistan
- Volunteers
- 77 people
- Sponsor
- Khyber Medical University Peshawar
Renal Tumor, Kidney Neoplasm
An MRI-Based Study of Intelligent Pathological Subtyping and Grading of Renal Tumors
This retrospective + prospective, non-interventional study aims to develop and evaluate artificial intelligence methods for the detection, pathological subtyping, and histological grading of renal tumors using magnetic resonance…
- Trial name
- NCT07743749
- Testing
- MRI-Based Artificial Intelligence Analysis
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Cerebrovascular Stroke, Stroke, Acute
Safety and Effectiveness of SOFIA™/SOFIA™ PLUS for Direct Aspiration in Acute Ischemic Stroke
Sesame is a European, multi-center, single arm, prospective, observational registry. Sesame aims to demonstrate that use of SOFIA™/SOFIA™ PLUS catheter for direct aspiration as a first line treatment technique is fast, safe and…
- Conditions
- Cerebrovascular Stroke, Stroke, Acute, Cerebral Stroke
- Trial name
- SESAME (NCT03417349)
- Testing
- Sofia
- Where
- 15 sites in Austria, France and 3 more
- Volunteers
- 250 people
- Sponsor
- Dr. Markus Alfred Möhlenbruch
Headache
Utilization of 60-Day Peripheral Nerve Stimulation of the Occipital Nerves for the Treatment of Headache
This prospective observational cohort study will evaluate clinical outcomes and health care resource utilization among adults who, independent of research participation, are clinically scheduled to undergo temporary 60-day…
- Trial name
- NCT07553533
- Testing
- Occipital nerve peripheral nerve stimulation (PNS)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Yale University
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Aspergillus Fumigatus Infection
Aspergillosis and Humoral Alveolar Immunity by Proteomics
Aspergillus fumigatus is the most common opportunistic mold found in lung fungal infections in humans. Aspergillus is the cause of invasive pulmonary aspergillosis with a poor prognosis in immunocompromised patients and the…
- Trial name
- ASPEOMIC (NCT04728763)
- Testing
- Protein profile
- Volunteers
- 32 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
Risk Assessment and Management Program (RAMP) on Knee Osteoarthritis in Primary Care
The goal of this clinical trial is to determine the clinical effectiveness of a Chronic Care Model (CCM) named Risk Assessment and Management Program on Knee OA (RAMP-Knee OA) in adults with knee Osteoarthritis (Knee OA) at 52…
- Trial name
- NCT06283147
- Testing
- Risk assessment and Management Programme - Knee Osteoarthritis
- Where
- Hong Kong
- Volunteers
- 228 people
- Sponsor
- Chinese University of Hong Kong
Stroke, Acute Ischemic, Cognitive Impairment
Effect of Preventive Cognitive Training on Cognitive Impairment After Stroke in Acute Stage
Post-stroke cognitive impairment(PSCI) refers to a clinical syndrome characterized by cognitive impairment that occurs after a stroke event and persists for 6 months.
- Trial name
- NCT05648149
- Testing
- hierarchical multi-dimensional cognitive training scheme based on computer
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Profound Hearing Loss, Cochlear Implants
The Value Electrical Stapedial Reflex Thresholds (eSRTs) Cochlear Implant Mapping
One of the most significant challenges in cochlear implant programming, particularly for very young children and those with an associated pathologies, is the measurement of subjective comfort levels (= C-Subjective).
- Trial name
- eSRT (NCT06051006)
- Testing
- ESR and ECAP measurements, Device setting, Speech audiometry
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus
AI-CARE: A Novel AI-Driven Mobile Insulin Calculator Integrating Image- Based Carbohydrate Estimation and CGM
AI-CARE is an artificial intelligence-enabled clinical decision support mobile application designed to support prandial insulin dosing in individuals receiving MDI, incorporating a "human-in-the-loop" approach to ensure user…
- Trial name
- AI-CARE (NCT07884526)
- Testing
- AI-CARE, Usual Care Group
- Where
- Singapore
- Volunteers
- 48 people
- Sponsor
- Tan Tock Seng Hospital
Malignant Tumor of Women's Reproductive System
Characterizing Malignant Tumors Using Ultrasound Doppler Imaging
The aim of this study is to determine whether Ultrasound Doppler imaging can identify malignant tumors at a very early stage.
- Trial name
- NCT03598335
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Polyhandicap
Intensive Psychomotor Rehabilitation on Cognitive Motor Abilities and Adaptive Capacity on Children With Polyhandicap
Primary objective of the study is to compare and evaluate the impact of intensive care of rehabilitation of psychomotor vs. the standard care on adaptive behaviour of children with polyhandicap at 12 months after randomization.
- Trial name
- REEDUC-PLH (NCT04280458)
- Testing
- Intentive rehabilitation, Routine care
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth
Prevention of Preterm Birth With a Pessary in Triplet
The incidence of multiple gestations has increased over the past years, mostly because of increased use of assisted reproductive technologies.
- Trial name
- NCT02601443
- Testing
- Cervical Pessary
- Where
- Italy
- Sponsor
- Federico II University
Major Abdominal Surgeries
Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions
This study investigates the effects of low-flow desflurane anesthesia in adult patients undergoing major abdominal surgery. The researchers will examine whether different low-flow strategies: Cause differences in the Bispectral…
- Trial name
- NCT07212543
- Testing
- Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Dolunay ARIK
Type 2 Diabetes
Enhancing Telemedicine for T2D
The goal of this pilot clinical trial is to assess feasibility of an intervention to deliver comprehensive, high-quality diabetes care through telemedicine among adults with type 2 diabetes who use insulin and have multiple…
- Trial name
- NCT06740435
- Testing
- Enhanced Telemedicine for Type 2 Diabetes, Usual Telemedicine Endocrinology Care for T2D
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Pelvic Floor Dysfunction
Pelvic Floor Dysfunction and Quality of Life in Patient Undergoing Gynecological Surgery
The purpose of the study is to assess the pelvic floor dysfunction and quality of life in patient undergoing gynecological surgery.Common gynecological surgeries done for prolapse, fibroids, and cervical abnormality and also for…
- Trial name
- NCT06875635
- Testing
- Pre and Post op pelvic floor muscle training, Only post op pelvic floor muscle training, Routine medical care
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ventilation Acquired Pneumonia
Effectiveness of Oropharyngeal Suctioning in Preventing Ventilator-Associated Pneumonia: A Randomized Controlled Trial.
Ventilator-Associated Pneumonia (VAP) is a serious infection that affects patients who are on mechanical ventilation in intensive care units (ICUs).
- Trial name
- NCT07128537
- Testing
- Scheduled Oropharyngeal Suctioning Every 4 Hours, Standard Oral Care (Twice-Daily Brushing)
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
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