Clinical trials: Routine care
Sjögren Syndrome
Dental and Periodontal Status of Patients With Sjögren's Syndrome.
Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear…
- Trial name
- CB-SJO (NCT04848870)
- Testing
- Salivary samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oxygen, Postoperative Nausea and Vomiting
The Effect of Oxygen Given to Patients in the Postoperative Period on Nausea and Vomiting
Carbon dioxide which is insufflated to inflate the abdominal area is absorbed from the peritoneal area and it increases endogenous catecholamines, which may consequently increase nausea and vomiting.
- Trial name
- NCT04597723
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Parent-Child Relations, Child Development
FamilieTrivsel i Almen Praksis: a Mentalisation Programme for Families With Young Children
This cluster randomised trial aims to establish the effectiveness of an online intervention designed to improve the ability of parents to 'mentalise' - in other words to understand their own mental states and that of others…
- Conditions
- Parent-Child Relations, Child Development, Parenting
- Trial name
- NCT04129359
- Testing
- FamilieTrivsel, enhanced care as usual
- Where
- Denmark
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Cardiac Surgery
Preoperative Intervention to Reduce Delirium After Cardiac Surgery
This research is designed for experimental quantitative research and is conducted by simple random sampling. Both the control group and the experimental group provided preoperative routine nursing treatment and preoperative…
- Trial name
- NCT05143580
- Testing
- Cognitive therapy, Routine care
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Active Secondary Progressive Multiple Sclerosis
Impact of Mayzent on aSPMS Patients in a Long-term NIS in Italy
This is an observational, multicenter, single-arm, prospective study conducted in Italy
- Trial name
- ITASIA (NCT05376579)
- Testing
- siponimod
- Where
- 24 sites in Italy
- Volunteers
- 134 people
- Sponsor
- Novartis Pharmaceuticals
Perineal Trauma, Ritgen Maneuver
Ritgen Maneuver and Birth-Related Perineal Trauma: RCT
Perineal trauma is one of the common complications that may occur during the second stage of labor and can negatively affect women's postpartum recovery and quality of life.
- Trial name
- NCT07713173
- Testing
- Ritgen maneuver, Routine Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medipol University
Hypertension
Optimised Treatment for Hypertension Trial
This randomized trial compares two prescribing strategies to treat high blood pressure. One approach involves remote treatment informed by randomized trial evidence without regular monitoring of blood pressure ("fire and…
- Trial name
- OPTIMISE-BP (NCT06935760)
- Testing
- Fire and forget, Usual care with more intensive BP monitoring
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- The George Institute
Atrophic Edentulous Maxilla
Patient-specific Finite Element Analysis of Immediate Loading in the Edentulous Maxilla: Comparison of Three Implant Configurations Using Digital Twins.
Rehabilitation of severely atrophic edentulous maxillae with dental implants pose a significant clinical challenge. Immediate loading in grafted bone is often debated due to concerns about stress distribution and…
- Trial name
- NCT07266896
- Testing
- numerical study
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gastrointestinal Dysfunction, Malnutrition
Postoperative GI Dysfunction and Nutrition in Malnourished Cancer Surgery Patients
This is a prospective two-center observational cohort study in adult patients undergoing major abdominal and/or pelvic oncologic surgery with pre-existing malnutrition.
- Conditions
- Gastrointestinal Dysfunction, Malnutrition, Delirium - Postoperative, Abdominal Neoplasm
- Trial name
- GIDNUT (NCT07622888)
- Testing
- Serotonin (e.g., serotonin adipinate), Standard Prokinetic Therapy (excluding serotonin)
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Arma Ltd.
Esophageal Cancer
Comparison of Nab-Paclitaxel Versus Paclitaxel in Neoadjuvant Immunochemotherapy Therapy for Esophageal Squamous Cell Carcinoma: A Retrospective IPTW-Adjusted Analysis
Taxane-based agents are widely used in the treatment of esophageal squamous cell carcinoma (ESCC). Among these, nab-paclitaxel (albumin-bound paclitaxel) and paclitaxel are the most commonly used.
- Trial name
- NCT07549269
- Testing
- The cohort included 161 patients treated with solvent-based paclitaxel and 226 treated with nanoparticle albumin-bound paclitaxel.
- Where
- 3 sites in China
- Volunteers
- 387 people
- Sponsor
- Sichuan University
Chronic Obstructive Pulmonary Disease (COPD)
Walk On! Physical Activity Coaching
Chronic obstructive pulmonary disease (COPD) is the third leading cause of the death in the US. The personal, social and economic costs of the disease are tremendous, with annual expenditures of nearly $50 billion, mostly from…
- Trial name
- NCT02478359
- Testing
- Physical Activity Coaching (Walk On!)
- Where
- United States
- Volunteers
- 2,707 people
- Sponsor
- Kaiser Permanente
Anxiety, Hemodynamic Instability
The Effect of Preoperational Hand Massage Anxiety Level And Hemodynamic Variables
The study was conducted randomly controlled experimental to determine the effect of hand massage applied to pre-operative children on anxiety level and physical symptoms of anxiety.
- Trial name
- NCT05324527
- Testing
- Hand Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Mersin University
Multiple Myeloma (MM), Self-care
The Effect of Mobile Application-Based Education Developed According to Orem's Self-Care Model in Multiple Myeloma Patients
This randomized controlled trial aims to assess the effectiveness of a mobile application-based education program, developed according to Orem's Self-Care Model, in improving self-care agency and quality of life among patients…
- Conditions
- Multiple Myeloma (MM), Self-care, Quality of Life
- Trial name
- OCARE-MM (NCT07088783)
- Testing
- Mobile App Education
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Ozlem
COVID-19 Pandemic, Professional Stress
Mental Health of Professionals of the Silver Economy of New Aquitaine : Online Survey of Accommodation Establishments for Old People and Home Assistance Establishments
The purpose of this study is identify the psychological impact of the coronavirus-19 pandemic on professionals in residential care facilities for old people and home help professionals in New-Aquitaine by : 1.
- Trial name
- SILVER NA (NCT05381883)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
End-Stage Kidney Disease, End Stage Renal Disease (ESRD)
Dialysis Efficiency and Transporter Evaluation Computational Tool in Peritoneal Dialysis
The goal of this prospective diagnostic test (correlation) study is to develop and investigate the performance of artificial intelligence in predicting peritoneum transporter status and dialysis efficiency in adult patients…
- Conditions
- End-Stage Kidney Disease, End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis (Diagnosis), End Stage Renal Failure on Dialysis
- Trial name
- DETECT-PD (NCT06842927)
- Testing
- data collection, data report
- Where
- Hong Kong
- Volunteers
- 350 people
- Sponsor
- Tuen Mun Hospital
Small for Gestational Age at Delivery
Use of Customized GROW Charts for Detection of SGA in Low Risk Woman.
A prospective randomised control trial to evaluate the effectiveness of customised growth charts for detection of small for gestational age fetus in low risk women, in comparison to conventional standard of care.
- Trial name
- NCT04764461
- Testing
- Use of customised GROW Charts
- Where
- Pakistan
- Volunteers
- 1,000 people
- Sponsor
- Fatima Memorial Hospital
Children
The Impact of Helfer Skin Tap and ShotBlocker Techniques on Emotional Responses to Intramuscular Injections in Children
Study Aim: This study aims to determine the effects of the Helfer Skin Tap Technique (HST) and ShotBlocker application on pain, emotional indicators, and physiological parameters during intramuscular (IM) drug administration in…
- Trial name
- NCT06851182
- Testing
- Helfer skin tap technique, Shotblocker technique
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Inonu University
Fibromyalgia, Pain Syndrome
Effects of Fibromyalgia Education on Smart Phone Addiction, Pain, and Quality of Life
The study focuses on fibromyalgia, a condition characterized by chronic pain, fatigue, and associated issues like sleep disorders, depression, and anxiety.
- Conditions
- Fibromyalgia, Pain Syndrome, Addiction, Mobile Phone
- Trial name
- EFESAPQL (NCT06239779)
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Antalya Training and Research Hospital
Gestational Diabetes Mellitus
Home-Ultrasound in Routine High-Risk Care of Patients With Gestational Diabetes Mellitus (GDM)
This study evaluates the impact of incorporating home-ultrasound (home-US) devices into telemedicine care for patients with gestational diabetes mellitus (GDM).
- Trial name
- NCT07158970
- Testing
- Use of the Pulsenmore home ultrasound device for fetal assessment, guided remotely by a physician.
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Wolfson Medical Center
Tachyarrhythmia
Magnetic Resonance (MR) Conditional Tachyarrhythmia Therapy Products Post-approval Study
Following product approval, further confirmation of the MR Conditional Tachyarrhythmia Therapy Systems sensing and detection performance post MRI exposure will be obtained by actively monitoring de-identified device data obtained…
- Trial name
- NCT02849769
- Testing
- Implant of an MR-conditional Tachy device system
- Volunteers
- 10,979 people
- Sponsor
- Medtronic
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