Clinical trials: Routine care
First Episode Psychosis, Schizophrenia, Childhood
Early Psychosis Intervention - Spreading Evidence-based Treatment
Implementation of 'NAVIGATE' in Ontario aims to help youth and emerging adults suffering from a first episode of psychosis. Although Ontario already has early psychosis intervention programs, the team's recent work has identified…
- Conditions
- First Episode Psychosis, Schizophrenia, Childhood, Psychosis, Schizophrenia
- Trial name
- EPI-SET (NCT03919760)
- Testing
- NAVIGATE, Treatment as Usual
- Where
- 6 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Centre for Addiction and Mental Health
Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other
Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"
The purpose of this study is to evaluate the safety and efficacy on participants receiving first-line eradication and second-line eradication including vonoprazan (Takecab) tablets (triple therapy) in the routine clinical setting.
- Trial name
- NCT03219723
- Testing
- Vonoprazan, Amoxicillin hydrate, Clarithromycin
- Where
- Japan
- Volunteers
- 560 people
- Sponsor
- Takeda
HIV Infections, HIV Prevention
Community-based Outreach and Navigation for Nurse-led Engagement in HIV Care and Treatment
Many people who are experiencing homelessness are at high risk for HIV, but they often have trouble getting HIV prevention or treatment.
- Conditions
- HIV Infections, HIV Prevention, Homeless Persons, Homelessness
- Trial name
- CONNECT (NCT07870603)
- Testing
- CONNECT (status-neutral, nurse-led on-site HIV service delivery), Standard of Care (referral-based outreach)
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Donaldson Conserve
Pain Management, Analgesia, Postoperative
Pain Management Protocol in Abdominal Surgeries in City of Erbil
Intervention Our study involves a novel multimodal pain management protocol for postoperative pain management. The protocol consists of 4 main phases: preoperative, intraoperative, postoperative, and post-discharge phases with…
- Trial name
- EPMP (NCT07019103)
- Testing
- Gabapentin (Neurontin® (Registered Trademark))
- Where
- Iraq
- Volunteers
- 136 people
- Sponsor
- Haroon Muhammad Khalil
Chronic Post-operative Pain
Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery
Chronic postoperative pain (CPOP) after video-assisted thoracic surgery (VATS) is severe because it results from lesions at multiple levels: incisions, pulmonary or nerve contusions.
- Trial name
- EVADRAINS (NCT07108582)
- Testing
- no NSAID, protocol for administering NSAIDs already used in routine care
- Volunteers
- 270 people
- Sponsor
- University Hospital, Strasbourg, France
Diabetic Foot Disease, Diabetic Foot Ulcer (DFU)
Implementation of a Diabetic Foot Prevention Strategy in Primary Care (iMplanta Study)
The goal of this two-arm cluster randomised controlled trial (RCT) is to evaluate the effectiveness of a new implementation strategy based on the ImM model for the Protocol of assistance to the person with diabetic foot (PAPDF)…
- Trial name
- iMplanta (NCT07004179)
- Testing
- Implementation strategy developed using the Implementation Mapping model to enhance the effective integration of the Protocol for Assistance to People with Diabetic Foot
- Where
- Spain
- Volunteers
- 1,520 people
- Sponsor
- University of the Balearic Islands
Intensive Care Unit Patients, Physiotherapy and Rehabilitation
Effect of Abdominal Massage on Patients in Intensive Care Unit
Bowel motility can be affected by many factors such as immobilization, lack of fiber in the nutritional formula, inadequate fluid intake, and lack of privacy for toileting in patients hospitalized in the intensive care unit.
- Conditions
- Intensive Care Unit Patients, Physiotherapy and Rehabilitation, Abdominal Massage
- Trial name
- NCT06950580
- Testing
- abdominal massage
- Volunteers
- 128 people
- Sponsor
- Karadeniz Technical University
Chronic Urticaria
Role of Endothelial Cells in the Pathogenesis of Chronic Urticaria.
Chronic urticaria (CU) is a disease that usually affects a large visible amount of surface of the skin. It is accompanied by severe itch and feeling of burned skin.
- Trial name
- NCT03443362
- Testing
- Punch Biopsy, Blood sampling
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Olivier Michel
Atelectasis, Pulmonary Complications
Evaluation of The MetaNeb® System to Reduce Postoperative Pulmonary Complications
To determine if a therapy regimen including treatment with The MetaNeb® System had a positive impact on the rate of pulmonary complications related to atelectasis and/or secretion retention that occur in high risk post-operative…
- Trial name
- NCT02627742
- Testing
- MetaNeb® System
- Where
- 3 sites in United States
- Volunteers
- 419 people
- Sponsor
- Hill-Rom
Gastroesophageal Reflux Disease
Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: Can stellate ganglion block improve gastroesophageal reflux…
- Trial name
- NCT06215742
- Testing
- Rehabilitation therapy, Stellate ganglion block
- Where
- China
- Sponsor
- Zeng Changhao
Primary Amenorrhoea, Hypothalamic Amenorrhoea
Pubertal Induction in Individuals With Hypogonadism
The investigators wish to explore the variability of uterine, breast and bone outcome markers as surrogates to assess the adequacy of exogenous oestrogen replacement in individuals with hypogonadism.
- Conditions
- Primary Amenorrhoea, Hypothalamic Amenorrhoea, Hypogonadotrophic Hypogonadism, Hypopituitarism
- Trial name
- NCT02871986
- Testing
- Routine transdermal oestrogen patch
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
Irritability, Anger
CBT for Anger and Aggression in Children: a Pilot Study of Irritability and Suicidality
This pilot study evaluated whether cognitive behavioral therapy for anger and aggression, added to treatment as usual, was associated with reductions in irritability and suicidal ideation in preteen children with externalizing…
- Conditions
- Irritability, Anger, Externalizing Behavior, Suicidal Ideation
- Trial name
- NCT07603986
- Testing
- Cognitive Behavioral Therapy for Anger and Aggression, Treatment as Usual (TAU)
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Geha Mental Health Center
Chronic Kidney Diseases, Acute on Chronic Renal Failure
Effects of a Goal-Oriented Care Interventions
This study was a clinical trial. This study aimed to evaluate the effects of Goal-Oriented Care intervention on blood pressure, percentage of interdialytic weight gain, self-management behaviors, and quality of life in…
- Conditions
- Chronic Kidney Diseases, Acute on Chronic Renal Failure, Acute Kidney Injury
- Trial name
- NCT06068660
- Testing
- The Goal-Oriented Care program, The routine health education
- Where
- Taiwan
- Volunteers
- 92 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Hepatitis B
Union-FAST: An Intelligent-Agent Intervention to Increase Antiviral Treatment Uptake in Diagnosed-but-Untreated Hepatitis B Patients
The World Health Organization (WHO) has set a target to eliminate viral hepatitis by 2030, aiming for a 90% diagnosis rate and an 80% treatment rate for chronic hepatitis B (CHB).
- Trial name
- Union-FAST (NCT07520123)
- Testing
- Agent Intelligence education
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Missed Nursing Care, Patient Safety
Perioperative Nursing Workload, Missed Care, and Near-Miss Events
This prospective, single-center observational study examines the relationship between perioperative nursing workload and safety-critical perioperative nursing care in the operating rooms of Agri Training and Research Hospital.
- Conditions
- Missed Nursing Care, Patient Safety, Workload
- Trial name
- NCT07834580
- Testing
- Structured Direct Observation and Workload Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Cardiac Defects, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Chest CT With Iterative Reconstruction as an Alternative to Conventional Chest X-ray Prior to Heart Surgery
To assess if information about aortic calcification obtained from routine preoperative ultra low-dose chest CT lowers the postoperative stroke rate in patients undergoing heart surgery by optimizing surgical strategy compared to…
- Conditions
- Cardiac Defects, Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Stroke
- Trial name
- CRICKET (NCT02173470)
- Testing
- CT scan
- Where
- 3 sites in Hungary, Netherlands
- Volunteers
- 866 people
- Sponsor
- UMC Utrecht
Aspiration
Routine Point of Care Ultrasound (POCUS) Assessment of Antral Gastric Contents in Traumatic Surgical Patients for Prevention of Aspiration Pneumonitis
Pulmonary aspiration of gastric contents is uncommon in the elective, surgical populations, but highly prevalent in trauma patients who requires emergency surgery as trauma impair gastric motility and emptying.1 Presence of…
- Trial name
- NCT04083677
- Testing
- SONAR
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Postoperative Recovery, Length of Hospital Stay
The Effect of the Anticholinergic Burden Following Elective Coronary Artery Surgery
Anticholinergic drugs are common in older adults and linked to cognitive decline, frailty, longer hospital stay, and higher mortality.
- Conditions
- Postoperative Recovery, Length of Hospital Stay, Postoperative Complications
- Trial name
- NCT06349057
- Testing
- reducing anticholinergic burden
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Posttraumatic Stress Disorder
CBITS - Treat Trauma in Child Welfare
The goal of this randomized controlled trial is to evaluate the effectiveness of the trauma-focused group intervention CBITS compared with enhanced treatment as usual (TAU+) in child welfare programs in Germany.
- Trial name
- CBITS (NCT06038357)
- Testing
- CBITS, TAU+
- Volunteers
- 90 people
- Sponsor
- University Hospital Ulm
Critical Illness, Communication
Time Limited Trials to Reduce Non-Beneficial Intensive Care Unit Treatments
Overutilization of intensive care unit (ICU) treatments among patients with advanced medical illnesses and poor prognosis places them at risk for prolonged suffering with minimal anticipated benefit.
- Trial name
- NCT04181294
- Testing
- Family meetings using time limited trials as default ICU communication and care planning approach, Usual practice
- Where
- 3 sites in United States
- Volunteers
- 209 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
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