Clinical trials: Routine care
Pulmonary Arterial Hypertension
Mobile Health Intervention to Improve Exercise in Pediatric PH
Children and adults with pulmonary arterial hypertension (PAH) have severely reduced daily activity compared to healthy populations.
- Trial name
- MhOVE-PPH (NCT06549452)
- Testing
- mHealth Intervention, Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University Medical Center
Nonvalvular Atrial Fibrillation, Health, Subjective
Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects
This study intends to collect blood samples of adult healthy subjects, elderly healthy subjects and elderly patients with atrial fibrillation after taking dabigatran etexilate for pharmacokinetics and other studies, aiming to…
- Trial name
- NCT05715658
- Testing
- Dabigatran etexilate capsule
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dongyang Liu
Osteoporosis, Postmenopausal Osteoporosis
AGE Burden and Response to Antiresorptive Therapy in Osteoporosis
Osteoporosis is a common condition that increases the risk of bone fractures. Although antiresorptive treatments such as bisphosphonates and denosumab are effective in increasing bone mineral density, some patients continue to…
- Trial name
- NCT07329543
- Volunteers
- 240 people
- Sponsor
- Bursa City Hospital
Randomised Controlled Trial, Public Health Nursing
Program to Increase Fathers' Involvement in Infant Care
Fathers participating in the study will be given an 8-week formality intervention. Participants will be shown 4-week infant care training records and then 4-week videos prepared on educational topics.
- Conditions
- Randomised Controlled Trial, Public Health Nursing, Child Health
- Trial name
- Infant Care (NCT06969248)
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Acute Kidney Insufficiency, Anti-Infective Agent Toxicity
Computer-based Dosage Calculation for Antibiotics
Adequate dosing of antiinfective therapy in critically ill patients with impaired or lost renal function or continuous renal replacement therapy is nearly impossible without measuring the drug concentration in blood samples.
- Trial name
- NCT03036826
- Testing
- Piperacillin/tazobactam, Meropenem
- Where
- Germany
- Sponsor
- University Hospital Tuebingen
Age-Related Macular Degeneration (AMD), Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD
The Efficacy of Home OCT Supported Management in Patients Diagnosed With Neovascular-AMD and Undergoing a Drug Switch to Faricimab
Age-related macular degeneration (AMD) is a common eye disease that can lead to vision loss. The neovascular ("wet") form of AMD is usually treated with repeated injections into the eye.
- Trial name
- NCT07744984
- Testing
- Home Optical Coherence Tomography (Home OCT)
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Rabin Medical Center
Dental Pulp Diseases, Dental Pulp Necrosis
Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy
The purpose of this study is to to compare root canal therapy success between two root canal filler materials: 1) gutta percha (GP), 2) gutta percha modified with nanodiamonds and amoxicillin (NDGX).
- Conditions
- Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
- Trial name
- NDGX (NCT03376984)
- Testing
- ND and AMOX modified Gutta Percha, Gutta Percha
- Where
- United States
- Sponsor
- University of California, Los Angeles
Postoperative Shoulder Pain After Gynecologic Laparoscopy
Intraperitoneal Gas Drainage to Reduce Postoperative Shoulder Pain After Gynecologic Laparoscopy .
This randomized controlled trial aims to evaluate whether the use of an intraperitoneal gas drain at the end of gynecologic laparoscopic surgery can reduce postoperative shoulder pain.
- Trial name
- NCT07262749
- Testing
- Intraperitoneal Gas Drain
- Volunteers
- 124 people
- Sponsor
- Assiut University
Pulmonary Artery Hypertension
Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension
The primary objective of this study is to determine the impact of two interventions against insulin resistance on the composite endpoint of 10% improvement in baseline six minute walk distance or improvement in World Health…
- Trial name
- NCT03617458
- Testing
- Metformin, mHealth Intervention, Usual Care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Vanderbilt University Medical Center
Perineal Pain, Birth Satisfaction
The Effect of Birth Ball and Perineal Massage on Perineal Pain, Perineal Trauma and Birth Satisfaction
One of the important causes of perineal trauma is perineal tension. By reducing this tension, perineal trauma can be prevented. Perineal trauma is a birth complication that can be prevented with midwifery approaches.
- Conditions
- Perineal Pain, Birth Satisfaction, Perineal Laceration, Tear, or Rupture During Delivery
- Trial name
- NCT06935643
- Testing
- Birth Ball, Perineal Massage, Control Group
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Preterm
The Nonpharmacological Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants
According to the World Health Organization, preterm birth (from 20 to 37 gestation week) is a significant global health problem, as preterm infants represent an estimated 15 million infants per year worldwide.
- Conditions
- Pain, Preterm, Premature
- Trial name
- NCT04006743
- Testing
- The swaddling group, The expressed breast milk group, The facilitated tucking group
- Where
- Turkey (Türkiye)
- Volunteers
- 187 people
- Sponsor
- Akdeniz University
Breast Cancer, Breast Neoplasms
Biennial CEM in Women With a Personal History of Breast Cancer
This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in…
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Cancer Female, Neoplasms
- Trial name
- NCT06105749
- Testing
- contrast-enhanced mammography
- Where
- 6 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Wendie Berg
Inflammatory Bowel Diseases
Assessment of Colonic Epithelial Integrity With Mucosal Impedance
In this study, the investigators propose to use mucosal impedance (MI), a minimally invasive technology, to detect mucosal damage (i.e. barrier dysfunction) based on mucosal conductivity changes in the colonic epithelium.
- Trial name
- NCT03165058
- Testing
- mucosal impedance (MI) testing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Vanderbilt University Medical Center
Fecal Immunochemical Test
Efficacy of Fecal Immunochemical Test Using Digital Rectal Exam
This study will investigate the use of digital rectal exam (DRE) to obtain stool samples for the fecal immunochemical test (FIT) in patients due for screening colonoscopy and in pre-operative patients with known colorectal…
- Trial name
- FIT-DRE (NCT03013855)
- Testing
- FIT-SOC, FIT-DRE
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Lichen Sclerosus
Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of Life
This observational study aims to evaluate routine treatment outcomes in men with lichen sclerosus (LS), including a long-term follow-up to assess disease progression and histopathological changes.
- Trial name
- NCT06984263
- Testing
- Circumcision
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Västerbotten
Infertility
The Value of Addition of Human Menopausal Gonadotropin Drug Following Oocytes Retrieval in IVF Cycles
The aim of this study is to test the hypothesis that addition of daily small dose of human menopausal gonadotropin (HMG) drug following oocytes retrieval could improve the fertility outcome in women undergoing in-vitro…
- Trial name
- NCT03209687
- Testing
- human menopausal gonadotropin
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Cairo University
Depression
Assessing an EEG Biomarker of Response to TMS for Major Depression
Veterans with treatment resistant depression (TRD) have the opportunity to receive transcranial magnetic stimulation (TMS) treatment via the VA's National TMS Clinical Pilot Program.
- Trial name
- NCT05008198
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- VA Office of Research and Development
Lung Cancer, Pulmonary Nodule, Solitary
Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES
This is a pragmatic clinical trial that will study the effect of a radiomics-based computer-aided diagnosis (CAD) tool on clinicians' management of pulmonary nodules (PNs) compared to usual care.
- Trial name
- ARCADES (NCT05968898)
- Testing
- Optellum Virtual Nodule Clinic
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Breast Cancer
Developing Breast (Cancer) Organoids
Currently, only a few validated biomarkers and models exist guiding or predicting treatment response for specific patient groups.
- Trial name
- NCT05317221
- Testing
- Not an extra intervention, tissue taken in routine practice will be used.
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht Radiation Oncology
Breast Cancer, Chemotherapy
Smart VR Mindfulness for Breast Cancer: Integrating Biofeedback and Evaluating Chemotherapy Effectiveness
Breast cancer patients undergoing chemotherapy often face significant physical and emotional symptoms, with stress contributing to symptom severity.
- Conditions
- Breast Cancer, Chemotherapy, Virtual Reality, Mindfulness
- Trial name
- NCT06541587
- Testing
- mindfulness based virtual reality, mindfulness based audio practice
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Hsin Yi Lu
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.