Clinical trials: Routine care
Hypoglycemia Hyperglycemia
Pediatric Critical Illness Hyperglycemia and Glycemic Control Registry
The objective in this project is to assemble a consortium of pediatric critical care centers of varying size, acuity, and composition to evaluate our glycemic control protocol on at least 250 children with hyperglycemia in…
- Trial name
- NCT01116674
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Indiana University
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Cancer Terminal
Palliative Care for Elderly Outpatients
Our long-term goal is to improve spiritual care outcomes for elderly patients with cancer. The study team will use a spiritual intervention, Dignity Therapy (DT), to help these patients maintain pride, find spiritual comfort…
- Trial name
- NCT03209440
- Testing
- Dignity Therapy - Nurse Led, Usual care, Dignity Therapy - Chaplain Led
- Where
- United States
- Volunteers
- 579 people
- Sponsor
- University of Florida
Anxiety Fear, Prenatal Depression
Mentors Offering Maternal Support (M-O-M-S™): A Prenatal Program for Decreasing Maternal Anxiety and Depression
The M-O-M-S project evaluates the effectiveness of the M-O-M-S program for improving birth outcomes and maternal-infant attachment and role satisfaction in a large military sample.
- Conditions
- Anxiety Fear, Prenatal Depression, Infant, Low Birth Weight, Preterm Birth
- Trial name
- M-O-M-S (NCT03393637)
- Testing
- Mentors Offering Maternal Support (M-O-M-S)
- Where
- 3 sites in United States
- Volunteers
- 1,717 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Postoperative Care
Timing of Complications in the First 24 Hours After Admission to a Postoperative
The optimal duration and intensity of intensive care monitoring after surgery is largely determined by clinical experience rather than by objective, time-based evidence.
- Trial name
- POSTICU-24 (NCT07856537)
- Where
- Turkey (Türkiye)
- Volunteers
- 480 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Obesity, Spine Condition
Longitudinal Changes in Spinopelvic Alignment and Sagittal Balance After Bariatric Surgery in Patients With Morbid Obesity: A Prospective Observational Study
The goal of this prospective observational study is to understand how major weight loss after bariatric surgery may be associated with changes in the way the spine and pelvis are aligned in adults with morbid obesity.
- Trial name
- BARISPINOALIGN (NCT07794553)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Psoriasis
Canadian Real World Evidence Study of Brodalumab in Plaque Psoriasis to Understand the Impact on Quality of Life and Work Productivity
This is a phase IV, 12-month observational, prospective, open-label, multi-center study that will be conducted across approximately 50 sites in Canada for an estimated study duration of 32 months.
- Trial name
- CARE (NCT05132231)
- Testing
- Brodalumab, Matched cohort
- Where
- 42 sites in Canada
- Volunteers
- 394 people
- Sponsor
- Bausch Health Americas, Inc.
Acute Myocardial Infarction (AMI), Periodontal Disease
Myocardial Infarction and Periodontitis: Periodontal Health Intervention.
The aim of this study is to establish a shared database of acute myocardial infarction patients with periodontitis, to clarify the clinical benefits of periodontitis intervention on acute myocardial infarction patients through…
- Trial name
- NCT06745141
- Testing
- Periodontal surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Inguinal Hernia, Postoperative Pain
TENS for Pain and Sleep After Hernia Surgery
This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Sleep Disturbance
- Trial name
- TENS-HERNIA (NCT07319754)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Lower Limb Length Discrepancy (LLD) in Children
Analysis of the Biomechanical Impact of Lower Limb Length Inequality in PEDiatrics
Lower limb length discrepancy (LLD) is a frequent condition in pediatric orthopedics. Even moderate discrepancies can induce pelvic obliquity and compensatory scoliosis, modifying the distribution of joint loads at the hips and…
- Trial name
- ABILMI-PED (NCT07254351)
- Testing
- EOS Imaging System, Force Platform (Bertec®, integrated into EOS cabin)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Obstructive Sleep Apnea, Down Syndrome (Trisomy 21)
Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome
Obstructive Sleep Apnea (OSA) is characterised by repetitive collapse of the upper airway during sleep, inducing breathing disturbances that can result in oxygen desaturation and frequent arousals.
- Trial name
- OMF21 (NCT07195253)
- Testing
- Polysomnography (PSG) to explore OSA, Oro-myo-functional clinical evaluation, Sleep Disturbance Scale for Children
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer
This phase II trial studies how well docetaxel or paclitaxel work in reducing chemotherapy-induced peripheral neuropathy in African American patients with stages I-III breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT04001829
- Testing
- Docetaxel, Paclitaxel, Quality-of-Life Assessment
- Where
- 482 sites in United States
- Volunteers
- 249 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Stress Urinary Incontinence
MoVo-guided Traditional Chinese Kegel Exercises for Preventing Postpartum Urinary Incontinence.
The goal of this clinical trial is to determine whether a prenatal exercise program integrating Liuzijue qigong with traditional levator ani training, guided by the MoVo (Motivation-Volition) theory and delivered via a supervised…
- Trial name
- NCT07742202
- Testing
- Routine Verbal Instruction Group, App-Supervised Kegel Exercise Group, Liuzijue & Levator Ani Training Group
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yu xin Qian
Dry Eye Disease (DED), Glaucoma
Blinking Exercise Study
The goal of this clinical trial is to evaluate whether a structured blinking exercise can improve symptoms and signs of dry eye disease (DED) in adults with glaucoma who are using topical intraocular pressure-lowering…
- Trial name
- NCT07554937
- Testing
- Structured Blinking Exercise Training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
BPSD (Behavioral and Psycological Symptoms of Dementia)
Psychosocial Intervention for Behavioral Symptoms in Hospitalized Patients With Dementia or Delirium
Behavioral and psychological symptoms are common among older adults hospitalized with dementia or delirium and may include agitation, wandering, delusions, hallucinations, aggression, oppositional behavior, and sleep…
- Trial name
- ESSECOA (NCT07778329)
- Testing
- Sensory and General Stimulation With Caregiver Education, Standard Pharmacological Management
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Polypharmacy, Adverse Drug Reaction
Educational Intervention to Reduce Drug-related Hospitalizations in Elderly Primary Health Care Patients
The purpose of this study is to determine whether an educational intervention given towards health care providers working in primary health care centers can reduce inappropriate prescribing in the elderly patient and thus reduce…
- Trial name
- NCT01732302
- Testing
- Educational intervention
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Karolinska Institutet
Mucopolysaccharidoses
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis
Mucopolysaccharidosis (MPS) are a group of inherited, metabolic diseases caused by a deficiency of lysosomal enzymes that degrade glycosaminoglycans (GAGs).
- Trial name
- RespiGAG (NCT04112602)
- Testing
- Sputum, Tracheal aspiration
- Where
- 7 sites in France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Tours
Chronic Obstructive Pulmonary Disease
Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial
Background: Informative and supportive nursing care is essential to reduce complications and improve outcomes in Chronic Obstructive Pulmonary Disease (COPD) patients treated with Non-Invasive Ventilation (NIV).
- Trial name
- NCT04834037
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Epilepsy
Aromatherapy and Music on Sleep and Children With Epilepsy
Purpose: This study aimed to compare the effects of aromatherapy and music listening with routine care on sleep parameters and cerebral oxygenation in children with epilepsy.
- Trial name
- NCT07827729
- Testing
- Aromatherapy, Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kafkas University
Web
Web-based Preconceptional Care and Counseling, Risk Awareness, Healthy Lifestyle Behavior
Preconceptional (pre-pregnancy) care; It is a primary care preventive health service that aims to prepare individuals for pregnancy, to maintain and result in a healthy pregnancy process, and thus to contribute to the formation…
- Trial name
- NCT06002451
- Testing
- WEB-BASED PRECONCEPTİONAL CARE AND COUNSELİNG
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
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