Clinical trials: Routine care, completed
Open Wound Abdominal Wall, Wound Non Healing
Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy
This study evaluates the therapeutic effect of Oasis® Matrix along with Negative Pressure Wound Therapy (NPWT) on pressure wounds. Either Oasis or standard foam will be applied to the wound prior to activating the NPWT.
- Trial name
- NCT02246608
- Testing
- NPWT Standard of Care plus Oasis wound product, Routine NPWT Standard of Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Kettering Health Network
SCD
Effect of Virtual Reality on Pain and Function in Children With Sickle Cell Disease: A Randomized Controlled Trial
Significance or rationale of the study: Virtual reality (VR) is a promising non-pharmacological pain management tool. It enhances motor function by promoting cortical reorganization and neuroplasticity.
- Trial name
- RCT (NCT05952817)
- Testing
- virtual reality
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Afnan Bkri
Postoperative Pain, Lumbar Spine Surgery
Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal Surgery
This prospective observational study aims to evaluate the effect of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia in patients undergoing lumbar spinal surgery.
- Conditions
- Postoperative Pain, Lumbar Spine Surgery, Postoperative Analgesia
- Trial name
- NCT07326774
- Testing
- QIPB, LAI
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Type 1 Diabetes Mellitus
Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM
The purpose of this study is to demonstrate the safety and feasibility of a decision support system aimed at reducing glucose variability in T1DM patient using an insulin pump.
- Trial name
- NCT02558491
- Testing
- Decision Support System, Usual Care
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Daniel Chernavvsky, MD
Cataract Surgery, Intraocular Lens Position
The Effect of Capsulotomy Size on Effective Lens Position in Robotic Laser Cataract Surgery
The goal of this clinical trial is to learn whether the size of the opening made during laser-assisted cataract surgery affects where the artificial lens sits in the eye and the glasses prescription after surgery.
- Conditions
- Cataract Surgery, Intraocular Lens Position, Refractive Outcomes After Cataract Surgery, Cataract
- Trial name
- PRECISE (NCT07856849)
- Testing
- Femtosecond Laser Capsulotomy - Small Size (4.6 mm), Femtosecond Laser Capsulotomy - Large Size (5.6 mm)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Twin Cities Eye Consultants
Chronic Heart Failure With Reduced Ejection Fraction
An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States
This is an observational study in which data already collected from people with chronic heart failure with reduced ejection fraction (HFrEF) are studied.
- Trial name
- HOVER (NCT06363110)
- Testing
- Vericiguat (Verquvo, BAY1021189)
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Bayer
Attention-Deficit/Hyperactivity Disorder (ADHD)
Evaluating Clinical Outcomes of Treatment Effectiveness for Children and Adults With ADHD
To evaluate clinical effectiveness of medication treatment for ADHD. It is hypothesized that the effectiveness is lower than efficacy outcomes measured in clinical trials
- Trial name
- NCT00307268
- Where
- Canada
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dry Eye, Cataract Surgery
Efficacy Evaluation of SYSTANE® ULTRA in Patients Scheduled for Cataract Surgery
The purpose of this study is to evaluate the effectiveness of FID 112903 (SYSTANE ULTRA® Lubricating Drops) plus standard of care to standard of care alone, in subjects with a history of intermittent eye irritation or dryness…
- Trial name
- NCT01199510
- Testing
- FID 112903 (SYSTANE® ULTRA Lubricant Eye Drops) plus standard of care, Standard of Care
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Loneliness
Beyond Older Adults' Reablement.
The goal of this feasibility study is to find out if routine referrals of older adults aged 65years and over to community activities provided by third sector organisations will reduce their loneliness risk.
- Trial name
- NCT06616935
- Testing
- Intervention group one, community activities., Intervention group two
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- The University of Northampton
Overweight and Obesity
SHAPE AND MOTION - Medical Accompanied Slimming
Background: Overweight and obesity affect health, quality of life and ability to work. Therefore, the scientifically evaluated program "SHAPE AND MOTION - medically ◦ accompanied ◦ slimming" was developed to support overweight…
- Trial name
- SAMMAS (NCT03417674)
- Testing
- Lifestyle intervention
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- West German Center of Diabetes and Health
Coronary Artery Disease, Coronary Stenosis
Retrospective Algorithm Validation of IVUS-FFR in Patients
This is a retrospective, single-center study to develop and validate an updated algorithm for computing fractional flow reserve from intravascular ultrasound images (IvusFFR v2.0).
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Algorithm Validation for Fractional Flow Reserve Derived From Intravascular Ultrasound
- Trial name
- V-IVUS_FFR (NCT07551518)
- Testing
- No Intervention (Retrospective Data Analysis)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypothermia, Newborn
The Effect of Nursing Interventions on Body Temperatures of Infants
Aim: This study planned the intervention and care of term and preterm newborns treated in neonatal intensive care units, including thermoregulation, procedure duration and care with the opening technique of incubator covers.
- Trial name
- NCT06654479
- Testing
- In the newborns in the study, changes in body temperatures during routine nursing interventions of the nurses of the clinic were examined.
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Izmir Katip Celebi University
Gastrointestinal Symptoms
The Effect of Abdominal Massage Applied to Patients by Caregivers in Palliative Care Clinics on Gastrointestinal Symptoms
The aim of this study is to examine the effect of abdominal massage applied by caregivers to patients in palliative care clinics on gastrointestinal symptoms.
- Trial name
- NCT07244302
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Saglik Bilimleri Universitesi
Essential Hypertension, Sleep Quality
Sleep Hygiene Education and Blood Pressure Control in Essential Hypertension in Primary Care
This randomized controlled trial evaluated the effect of a brief sleep hygiene education program on sleep quality and blood pressure in adults with essential hypertension attending a family practice center in southern Türkiye.
- Conditions
- Essential Hypertension, Sleep Quality, Primary Care
- Trial name
- NCT07257237
- Testing
- Sleep hygiene education program
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Ozturk Gurer Tutu, MD
Alcohol, Drinking, Alcohol Use Disorder
Sustaining Patient-centered Alcohol-related Care
Alcohol use is the third greatest cause of disability and death for US adults. Care for unhealthy alcohol use is lacking in most primary care settings.
- Trial name
- SPARC (NCT02675777)
- Testing
- Quality Improvement Intervention
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Breast Cancer
Comparing (SIS.NET) to Standard Care in Patients Who Have Completed the Acute Phase of Treatment for Early Breast Cancer
This is a pilot study that will compare two systems of breast cancer follow up care and will evaluate a number of parameters indicating quality and efficiency of care delivery as well as patient satisfaction with care.
- Trial name
- CC077515 (NCT01308775)
- Testing
- SIS.NET, Routine Follow-up
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of California, San Francisco
Caregiver Stress in Chronic Mental Illness, Psychosocial Burden in Psychiatric Caregivers
Effect of a Mindfulness-Based Stress Reduction Program on Caregivers
This study is designed to investigate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on cognitive control and flexibility, psychological well-being, and self-compassion among primary caregivers of individuals…
- Conditions
- Caregiver Stress in Chronic Mental Illness, Psychosocial Burden in Psychiatric Caregivers, Chronic Mental Illness Caregiving, Cognitive and Emotional Outcomes in Caregivers
- Trial name
- MBSR-CG (NCT07322081)
- Testing
- The Mindfulness-Based Stress Reduction program consists of structured mindfulness practices, psychoeducation, and experiential exercises delivered to caregivers., Usual Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pregnancy, Gestational Diabetes
Targeted Lifestyle Change Group Prenatal Care
To conduct a randomized trial to determine the effect of Targeted Lifestyle Change Group Prenatal Care (TLC) on maternal and neonatal outcomes in women at high risk for developing gestational diabetes mellitus (GDM).
- Trial name
- TLC (NCT04090307)
- Testing
- TLC Group Prenatal Care
- Where
- 2 sites in United States
- Volunteers
- 305 people
- Sponsor
- University of North Carolina, Chapel Hill
GI Cancer
Development of Early Detection Signs for Gastrointestinal Cancer
Therapies involving the immune system have already shown great promise in early clinical trials for the treatment of renal cell carcinoma and melanoma.
- Trial name
- NCT00633334
- Testing
- Specimen bank
- Where
- United States
- Volunteers
- 2,499 people
- Sponsor
- University of Pittsburgh
Breast Cancer, Fatigue
Combined Strength Training and Functional Endurance Exercise Regimen on Cancer -Related Fatigue and Physical Performance
Primary Objective: -Determine if a specific exercise regimen (combined strength training/functional endurance) reduces the level of fatigue among women with breast cancer while undergoing adjuvant or neoadjuvant chemotherapy…
- Trial name
- NCT00421057
- Testing
- Combined Strength Training and Functional Endurance Exercise, Questionnaire
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- M.D. Anderson Cancer Center
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