Clinical trials: Routine care
Cigarette Smoking, Veterans
Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment
Veterans with substance use disorders smoke at extraordinarily high rates and have high rates of smoking-related death and disease.
- Trial name
- Co-STOP (NCT07809854)
- Testing
- Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn
The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants
Sustained inflation (SI) has been reported to be effective for reducing the need for intubation and/or invasive ventilation in preterm infants.
- Conditions
- Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn, Respiratory Morbidity
- Trial name
- NCT03165305
- Testing
- Sustained Inflation
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Planter Fasciitis
Effect of Primal Reflex Release Technique on Pain and Function in Plantar Fasciitis Patients
The plantar fascia at the foot bottom causes pain and inflammation which affects this thick tissue that runs from heel bone to toe.
- Trial name
- NCT07079566
- Testing
- Primal Reflex Release Technique (PRRT)he Primal Reflex Release Technique (PRRT) is a hands-on, non-invasive therapeutic approach designed to deactivate overactive protective reflexes believed to contr, Conventional Physiotherapy Treatment This reflects the standard care or routine treatment used as a comparison in your randomized controlled trial on plantar fasciitis. Let me know if your control gr
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Acute Hypoxemic Respiratory Failure
Predicting High-Flow Nasal Cannula Failure in Acute Hypoxemic Respiratory Failure Using Metabolomics and Clinical Data
The goal of this observational study is to determine whether metabolomic profiles combined with clinical data can predict high-flow nasal cannula (HFNC) failure and help optimize respiratory support in adult patients with acute…
- Trial name
- META-RESPIRE (NCT07607080)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital del Mar Research Institute (IMIM)
Congenital Microtia
Application and Effectiveness of the Perioperative Position Management Based on the ADDIE Model in Patients With Congenital Microtia
Aims and objectives: To evaluate the clinical application and effectiveness of a perioperative position management program constructed using the ADDIE model for patients with congenital microtia.
- Trial name
- NCT06569927
- Testing
- Utilization of a perioperative position management protocol for congenital microtia patients based on the ADDIE model.
- Where
- China
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Aging, Obesity & Overweight
Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock
This study examines whether routine treatment with semaglutide or tirzepatide, prescribed with lifestyle coaching in a real-world weight-management program, is associated with changes in biological age measured by the LinAge2…
- Trial name
- NCT07444073
- Testing
- Not applicable. This is an observational study.
- Where
- 2 sites in Singapore
- Volunteers
- 440 people
- Sponsor
- National University of Singapore
Sleep Apnea, Obstructive
Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics
Obstructive sleep apnea (OSA) is a highly prevalent disease resulting from dynamic upper airway collapse during sleep. Continuous positive airway pressure (CPAP) is highly efficacious but high rates of non-adherence to CPAP…
- Trial name
- NCT05429983
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Viraemia
Determining a Viral Load Threshold for Treating Cytomegalovirus (CMV)
This study aims to determine: a) whether those patients with 'low level' viral load results (between 200 and 3,000 copies/ml) could be monitored as opposed to starting preemptive therapy with valganciclovir, ganciclovir and/or…
- Trial name
- NCT00947141
- Testing
- ganciclovir (start when CMV PCR >200copies / ml x2), Monitor (Treatment starts when CMV PCR >3,000 copies / ml), Stop treatment when 2 levels CMV PCR <3,000 copies / ml
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- University College, London
Vascular Access Device Complications, Catheterization, Peripheral
Does a Novel Needle Over Catheter Device Improve First Pass Success and Decrease Complications
Emergency Department Patients who were to get intravenous (IV) access through routine medical care will receive it through trademarked catheter via convenience sample.
- Trial name
- NCT06547294
- Testing
- Osprey IV, Historical Controls
- Where
- United States
- Sponsor
- Community Medical Center, Toms River, NJ
Psychosis
A Large Pragmatic Cluster Randomized Controlled Trial of a Multi-element Psychosocial Intervention for Early Psychosis
Multi-element interventions for first-episode psychosis (FEP) are promising but have mostly been conducted on non epidemiologically representative samples in experimental settings, raising the risk thereby of underestimating the…
- Trial name
- GETUP-PIANO (NCT01436331)
- Testing
- Treatment As Usual (TAU), TAU+CBT for pts+Family Intervention+CM.
- Where
- Italy
- Volunteers
- 626 people
- Sponsor
- Universita di Verona
Sudden Infant Death Syndrome
The Effect of the Use of Mobile App
This randomized controlled trial aims to evaluate the effect of using the ABÖS-M mobile application, developed for mothers with newborns, on maternal knowledge, care skills, and self-efficacy levels related to Sudden Infant Death…
- Trial name
- NCT07032402
- Testing
- Education and Counseling, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amasya University
Uremic Pruritus
Using of Extra Virgin Olive Oil in Hemodialysis Patients to Improve Pruritus and Sleep Disorders
Background and Purpose: Itching is a common complication of hemodialysis patients, which can cause skin damage and affect the patient's comfort.
- Trial name
- NCT05466045
- Testing
- Olive oil application in hemodialysis patients with pruritus, Normal saline application in hemodialysis patients with pruritus
- Volunteers
- 86 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes, Diabetes Mellitus
The Impact of the Self-efficacy Building Nursing Program on Foot Self-care Confidence and Perceived Risk of Diabetes-related Foot Complications Among Diabetic Elderly Patients: A Randomized Virtual Based Trial
Abstract Background: Diabetes-related foot complications are a major cause of morbidity among elderly patients with diabetes, often exacerbated by inadequate self-care practices and low self-efficacy.
- Conditions
- Diabetes, Diabetes Mellitus, Foot Care
- Trial name
- foot self-care (NCT06973850)
- Testing
- The Self-Efficacy Building Nursing Program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Hypnosis, Preoperative Anxiety
Effect of Clinical Hypnosis in Preoperative Anxiety Among Patients Undergoing an Abdominal Surgery.
This Multicenter randomized controlled trial evaluates clinical hypnosis efficacy for reducing perioperative anxiety and postoperative pain in abdominal surgery patients across 3 Moroccan centers (n=48-68).
- Conditions
- Hypnosis, Preoperative Anxiety, Postoperative Pain, Abdominal Surgeries
- Trial name
- Hypnoanxiety (NCT07370974)
- Testing
- Clincal hypnosis
- Where
- 3 sites in Morocco
- Volunteers
- 48 people
- Sponsor
- HASSAN 1st university
Support of the Family as a Caregiving System
The Effect of an Electronic Decision Support System on Preventing Pressure Ulcers and Urinary Infections in Home Care
This study evaluated Care-Up, a mobile-compatible web-based decision support system for informal caregivers of patients receiving home healthcare.
- Trial name
- CARE-UP (NCT06927479)
- Testing
- Care-Up Electronic Decision Support System
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Akdeniz University
Heart Failure
Effectiveness of a Website and Telemonitoring in Patients With Heart Failure.
The number of people with heart failure is increasing in the western world. Mainly due to better treatment of myocardial infarctions and ageing of the population. The amount of health care workers is unfortunately not increasing.
- Trial name
- NCT01755988
- Testing
- Educational website (in addition to usual care)., Website and interactive platform with telemonitoring.
- Where
- 4 sites in Netherlands
- Volunteers
- 450 people
- Sponsor
- UMC Utrecht
Older Adults Living in Residential Care Facilities
The Assisted Lifestyle-Intergrated Functional Exercise Program in Older Adults Living in Residential Care Facilities
More than half of older adults living in care homes experience a fall each year, which can cause serious injuries, hospital visits, and a loss of independence.
- Trial name
- ALIFE (NCT07835503)
- Testing
- ALIFE exercise program, OTAGO exercise program
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The Hong Kong Polytechnic University
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
Experimental Study Designs
Exercises on CIPN, Fatigue, and Quality of Life in Colon Cancer Patients Receiving Chemotherapy
Objective: Cancer is one of the biggest global health threats. The incidence and mortality of colorectal cancer (CRC) are increasing.
- Trial name
- NCT05136573
- Testing
- Combined Exercises
- Volunteers
- 20 people
- Sponsor
- Chi Mei Medical Hospital
Hypertension in Pregnancy
SASH Study - Sonographic Assessment for Severe Hypertension in Pregnancy
Adjunctive use of easily-obtainable maternal sonographic vascular measurements assessing volume status, cardiac output, and systemic vascular resistance by means of inferior vena cava collapsibility/caval index (ICV CI)…
- Trial name
- SASH (NCT03783169)
- Testing
- Cardiovascular Sonographic Assessment
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
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