Clinical trials: Sevoflurane, completed
Anesthesia, Drug Effects
Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers
In imaging functional connectivity (FC) analyses of the resting brain, alterations of FC during unconsciousness have been reported.
- Trial name
- NCT02149927
- Testing
- Sevoflurane
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Anesthesia
Japan Phase 2/3 Clinical Study With BLM-240 (Desflurane)
The purposes of this study are to evaluate the efficacy and safety of desflurane (BLM-240) as an anesthetic agent and to demonstrate the non-inferiority of desflurane to sevoflurane in term of awakening/recovery from anesthesia.
- Trial name
- NCT00762372
- Testing
- desflurane, desflurane/nitrous oxide, sevoflurane/nitrous oxide
- Where
- 15 sites in Japan
- Volunteers
- 216 people
- Sponsor
- Baxter Healthcare Corporation
Low-flow Anesthesia
High vs. Low Flow Sevoflurane Anesthesia in Pediatric Laparoscopic Surgery: Recovery, Hemodynamics, and Cost Comparison
The primary objective of our study is to compare the effects of different flow rates of the routinely used inhalation agent, sevoflurane, on postoperative recovery times in pediatric patients undergoing elective laparoscopic…
- Trial name
- NCT06676969
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
COVID-19, Respiratory Failure
Comparative Study of Anaconda System Use Versus Conventional Sedation in COVID-19 Patients.
At the beginning of 2020, a global alert emerged which saturated intensive care units due to COVID-19 worldwide. This caused a need for mechanical ventilation due to atypical pneumonias that had a rapid evolution and respiratory…
- Trial name
- NCT06208592
- Testing
- Sevoflurane with AnaConDa
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- Hospital Español de Mexico
Ultrasound Guided Block, Pediatric Surgery
Mid-transverse Process to Pleura Block in Pediatric Thoracotomy
The aim of this study is to assess the effectiveness of analgesia of US guided MTP block in pediatrics undergoing thoracotomy.
- Conditions
- Ultrasound Guided Block, Pediatric Surgery, Analgesia
- Trial name
- NCT05999734
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD. However, there have been no evidence of which degree of partial neuromuscular blockade should be performed during LSR…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Neuromuscular Blockade
- Trial name
- NCT01613781
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Samsung Medical Center
Caesarean Section, Pregnancy
Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section
The project aims to introduce into clinical practice for Caesarean section conducted under general anesthesia with the rapid induction myorelaxation with rocuronium and the reversal of neuromuscular blockade by using sugammadex.
- Trial name
- RocSugIO (NCT01718236)
- Testing
- Rocuronium + sugammadex, Succinylcholine + Neostigmine
- Where
- 2 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Brno University Hospital
Anxiety, Separation, Psychomotor Agitation
Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Nearly 50% of young children undergoing surgery exhibit high level of anxiety during induction of anesthesia because of exposure to unfamiliar environment and people and separation from parents.
- Trial name
- NCT02027844
- Testing
- Cartoon, parental presence
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Yeungnam University College of Medicine
Tissue Oxygen Saturation
Tissue Oxygenation of the Tibial Anterior Muscle After Clamping of the Femoral Artery
Ischemic preconditioning is defined as protection from cell damage induced by prolonged ischemia by preceding cycles of short ischemia.
- Trial name
- NIRSFEM (NCT02038062)
- Testing
- Sevoflurane preconditioning
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Schleswig-Holstein
Anesthesia With Use of LMA (Laryngeal Mask Airway)
Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia
The aim of this study is first to assess if desflurane is superior in order to achieve a faster emergence from anesthesia.
- Trial name
- NCT02322502
- Testing
- Desflurane, Sevoflurane, propofol
- Where
- 4 sites in Germany
- Volunteers
- 352 people
- Sponsor
- RWTH Aachen University
Pain
Caudal Versus Intravenous Dexmedetomidine for Caudal Analgesia in Children
The aim of this prospective randomized double-blind study was to compare the analgesic efficacy and the side effects of dexmedetomidine (1 µg.kg-1) co-administered with bupivacaine for caudal analgesia or intravenously in…
- Trial name
- NCT02416063
- Testing
- Caudal Dexmedetomidine, Intravenous dexmedetomidine
- Volunteers
- 75 people
- Sponsor
- University of Jordan
Prostate Cancer
The Effect of Combined General/Epidural Anesthesia Versus General Anesthesia on Diaphragmatic Function
The aim of this study was to investigate whether robot assisted laparoscopic radical prostatectomy give rise to the impairment of diaphragmatic function postoperatively, and whether combined general/epidural anesthesia could…
- Trial name
- NCT01547416
- Testing
- epidural 250mL of 0.2% ropivacaine and 2 μg/mL of fentanyl, 5 mL/hr continuous infusion and 0.5 mL bolus dose, no epidural drug administered
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Exposure to Environmental Pollution, Adverse Effect of Unspecified General Anesthetic
Anesthetic Gas Leakage in Children During Tonsillectomy: a Comparison of Cuffed and Uncuffed Tracheal Tubes
Fires and operating room pollution may occur when anesthesia gases leak into the oropharynx during airway surgery. Investigators sought to measure the concentrations of anesthetic gases that leak into the mouth of children…
- Trial name
- NCT02725164
- Testing
- oxygen concentration, nitrous oxide concentration, carbon dioxide concentration
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Laparoscopic Surgery, Abdominal Surgery
Opioid Free Anesthesia in Abdominal Laparoscopic Surgery
Effectiveness of opioid free anesthesia using Dexmedetomidine to inhibit nociception in abdominal laparoscopic surgery
- Trial name
- NCT06394375
- Testing
- Dexmedetomidine, Fentanyl
- Where
- Indonesia
- Volunteers
- 74 people
- Sponsor
- Universitas Indonesia
Cognitive Dysfunction, Cognitive Disorder, Delirium - Postoperative
the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium
In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.
- Trial name
- NCT06597812
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amasya University
Pulmonary Aspiration
To Compare Effect of Sevoflurane Versus Desflurane on the Return of Swallowing Reflexes in the Elderly
Anaesthesia and surgery has become more common in the elderly as the population survives longer. Anaesthesia in the elderly confers a higher risk which is related to the aging process and the diseases that accompany seniority.
- Trial name
- NCT01833676
- Testing
- Sevoflurane, Desflurane
- Where
- Malaysia
- Volunteers
- 51 people
- Sponsor
- University of Malaya
Cognitive Dysfunction
Cerebral Oximetry With Near-infrared Spectroscopy and Negative Postoperative Behavioral Changes in Pediatric Surgery
The main objective of the present study was to evaluate whether cerebral oxygen saturation is associated with an increase of NPOBC in pediatric patients undergoing major surgery.
- Trial name
- NCT02773186
- Testing
- monitoring cerebral oxygen saturation
- Volunteers
- 198 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Hemodynamic Instability
Effect of Remimazolam and Propofol on Hemodynamic Stability During Anesthesia Induction in OPCAB Patients
Remimazolam is a novel ultra-short-acting benzodiazepine. Several studies demonstrated that its efficacy as a sedative hypnotics for general anesthesia is non-inferior to propofol.
- Trial name
- NCT05423951
- Testing
- REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO], Propofol, Rocuronium
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Seoul National University Hospital
NIR Spectroscopy
Influence of Cardiopulmonary Bypass, and Sevoflurane or Propofol Anesthesia, on Tissue Oxygen Saturation.
The purpose of the present study is to assess, by near infrared spectroscopy with INVOS oximeter during vascular occlusion test (VOT), the influence of cardiopulmonary bypass on tissue saturation in thenar muscle.
- Trial name
- NCT02593448
- Testing
- NIRS during VOT, General anaesthesia with propofol use, General anaesthesia with sevoflurane use
- Where
- Poland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Perioperative Respiratory Mechanics
Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective…
- Trial name
- VAPOR (NCT07295158)
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Konya City Hospital