Clinical trials: Sevoflurane, completed
Emergence Agitation
Melatonin for Pediatric Emergence Agitation
efficacy of melatonin premedication on emergence agitation in children undergoing herniorrhaphy surgeries
- Trial name
- NCT05223010
- Testing
- Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg
- Where
- Egypt
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Gastric Cancer
The Effect of Dexmedetomidine During Opioid Free Anesthesia on Postoperative Recovery After Gastrectomy
"Want to know the effect of dexmedetomidine during opioid free anesthesia on postoperative recovery after gastrectomy. Patients undergoing open gastrectomy are divided into dexmedetomidine group and control(remifentanil) group…
- Trial name
- NCT04529135
- Testing
- Dexmedetomidine, Remifentanil
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Gangnam Severance Hospital
Acute Respiratory Distress Syndrome
SEvoflurane for Sedation in ARds
This study evaluates whether a sedation with inhaled sevoflurane will decrease mortality and increase time off the ventilator at 28 days in patients with acute respiratory distress syndrome (ARDS).
- Trial name
- SESAR (NCT04235608)
- Testing
- Inhaled sedation with sevoflurane, intravenous sedation with propofol
- Where
- 33 sites in France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Clermont-Ferrand
Invasive Cancer, Pediatric Cancer
Comparing TIVA Using Propofol or Dexmedetomidine Versus Sevoflurane During Anaesthesia of Children Undergoing Bone-Marrow Aspiration
No doubt that children facing surgical procedures are subjected to perioperative distressing, anxious and worrying periods. Several factors included; parental deprivation, anxiety, previously mismanaged experience and…
- Trial name
- NCT05636566
- Testing
- Sevoflurane, Propofol infusion for maintance, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Hernia, Inguinal, Cryptorchidism
The Effect of Induction Technique on Postoperative Pain and Agitation
The objective of this study was to determine (a) whether patients anesthetized with intravenous propofol have less pain compared with sevofluorane for paediatric inguinal hernia and undescended testis operations and (b) whether…
- Trial name
- NCT02110745
- Testing
- Sevofluorane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Mustafa Kemal University
Arthritis Knee
Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.
Pain after a knee replacement can impair recovery and use of the new knee. Having an injection to numb the femoral nerve is known to give good pain relief after the operation but may lead to slower mobilisation as it also…
- Trial name
- LIFT (NCT02288923)
- Testing
- Femoral nerve block, Local Infiltration Analgesia, Sub arachnoid analgesia
- Where
- United Kingdom
- Volunteers
- 199 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Spinal Disease
General Anesthesia and Regional Cerebral Oxygenation inSpine Surgery Prone Position
Elderly patients are reportedly at higher risk of postoperative cognitive dysfunction (POCD).The authors hypothesized that the incidence of POCD would be affected by several factors including, the age of the patient, the degree…
- Trial name
- NCT05148637
- Testing
- Maintenance of general anesthesia by Sevoflurane, Maintenance of general anesthesia by Desflurane, Anesthesia was maintained by inhalational anesthesia (total intravenous anesthesia by lidocaine, propfol and fentanyl infusions)
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Opioid Use, Unspecified, Bariatric Surgery Candidate
Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery
A comparison of post-operative opioid use in laparoscopic bariatric surgery patients receiving opioid or opioid-free anesthesia.
- Conditions
- Opioid Use, Unspecified, Bariatric Surgery Candidate, Anesthesia
- Trial name
- NCT04081545
- Testing
- Opioid Anesthetics, Non Opioid Analgesics
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Christine Oryhan
Traumatic Brain Injury, Cerebral Oxygen Saturation
Effectiveness of Dexmedetomidine Versus Sufentanil on Cerebral Oxygen Saturation in Patients With Traumatic Brain Injury
This randomized controlled clinical trial aims to evaluate the effectiveness of dexmedetomidine compared with sufentanil on cerebral oxygen saturation in patients with traumatic brain injury (TBI) undergoing surgery under general…
- Conditions
- Traumatic Brain Injury, Cerebral Oxygen Saturation, NIR Spectroscopy
- Trial name
- DESTIN (NCT07244822)
- Testing
- Dexmedetomidine, Sufentanil
- Where
- Indonesia
- Volunteers
- 28 people
- Sponsor
- Universitas Jenderal Soedirman
Postoperative Pain, Anesthesia
Regional Anesthesia Versus General Anesthesia
Patients undergoing laparoscopic gynecological surgery will receive regional anesthesia or general anesthesia with endotracheal intubation.
- Trial name
- NCT03830086
- Testing
- Midazolam, Sufentanil, Propofol
- Where
- 2 sites in Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Anaesthesia
Aminophylline and Cognitive Function After Sevoflurane Anaesthesia
Early postoperative recovery of neurologic and cognitive functions is especially advantageous after fast-tracking ambulatory procedures to hasten home discharge after surgery.1 It is well known that volatile anaesthetic agents…
- Trial name
- NCT01022151
- Testing
- 0.2 mL/kg of aminophylline 10 mg/mL [group A2], 0.2 mL/kg of aminophylline 15 mg/mL [group A3], 0.2 mL/kg of aminophylline 20 mg/mL [group A4]
- Where
- Saudi Arabia
- Volunteers
- 180 people
- Sponsor
- King Faisal University
Low Flow Anesthesia, Sevoflurane Anesthesia
Ultra-Low-Flow Anesthesia and Carbon Footprint
This is a prospective, randomized controlled clinical trial evaluating the effects of ultra-low fresh gas flow (0.5 L/min) versus normal fresh gas flow (2.0 L/min) sevoflurane anesthesia in adult patients undergoing on-pump…
- Conditions
- Low Flow Anesthesia, Sevoflurane Anesthesia, Cardiac Surgery
- Trial name
- NCT07313969
- Testing
- ultra low flow anesthesia, normal flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Anesthesia
Volatile Anesthetics in Cardiac Protection
Patients undergoing stenting procedures, or cardiac or non-cardiac surgery could develop myocardial damage as testified by cardiac troponin release.
- Trial name
- NCT00364637
- Testing
- Sevoflurane (Volatile Anesthetic), Total intravenous anesthesia
- Where
- Italy
- Sponsor
- Università Vita-Salute San Raffaele
Anesthesia, Delirium
Anesthesia Depth Increases the Degree of Postoperative Dementia, Delirium, and Cognitive Dysfunction
Anesthetics and anesthesia are suspicious to induce dementia or aggravate preexistent cognitive deficits with or without evoking postoperative delirium.
- Conditions
- Anesthesia, Delirium, Dementia, Bispectral Index Monitor
- Trial name
- BIS & Dementia (NCT02382445)
- Testing
- Anesthesia depth monitor, propofol and sevoflurane
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- Heidelberg University
Anesthesia Monitor, Electroencephalography
Consistency Evaluation of the qCON, qNOX Indices and Bispectral Index
The first objective of this work is to compare the performances of three electroencephalogram based indices, the qCON index, the qNOX index and the bispectral index (BIS), in patients receiving gastrointestinal surgery during…
- Conditions
- Anesthesia Monitor, Electroencephalography, Sleep
- Trial name
- NCT04562181
- Testing
- Bispectral index and qCON/qNOX monitoring
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China Medical University, China
Congenital Heart Disease, Acute Kidney Injury
Effects of Anesthetic Techniques on Renal Function
This study evaluates Different effects of two anesthetic techniques on renal function during the perioperative period of cardiac surgery in children.
- Trial name
- NCT04030481
- Testing
- inhalation anesthesia, Total intravenous anesthesia
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Muscle Relaxation Caused by Sevoflurane
Effect of Sevoflurane on the Onset Characteristics and Intubating Conditions of Rocuronium
This study evaluates the potentiation of muscle relaxation caused by rocuronium by inhalational agent sevoflurane. Half the patients will be ventilated with oxygen ,nitrous oxide and sevoflurane during induction of anaesthesia…
- Trial name
- SRI (NCT02785653)
- Testing
- Sevoflurane, Rocuronium
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Maharashtra University of Health Sciences
Anesthesia, General, Surgical Oncology
General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial
This is a large pragmatic multicenter trial comparing maintenance of general anesthesia with total intravenous anesthesia using propofol versus volatile agent (sevoflurane, isoflurane, or desflurane) during cancer surgery.
- Trial name
- GA-CARES (NCT03034096)
- Testing
- Propofol, Volatile Agent
- Where
- 5 sites in United States
- Volunteers
- 1,826 people
- Sponsor
- Stony Brook University
Breast Neoplasms
Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision
Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably.
- Trial name
- CSIABTEC (NCT00575354)
- Testing
- Sevoflurane, Isoflurane
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Glaucoma, Intraocular Pressure
The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops
Pediatric glaucoma is a rare but potentially blinding condition where the pressure in the eye is too high. Diagnosis is based on intraocular pressure (IOP) and assessment of the optic nerve, cornea and other structures.
- Conditions
- Glaucoma, Intraocular Pressure, Anesthesia
- Trial name
- IOP (NCT01925391)
- Testing
- Tono-pen XL Applanation tonometer + Ocu-film +
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Miami