Clinical trials: Sevoflurane, completed
Anesthesia
Propofol or Sevoflurane Anesthesia in Egyptian Patients
The proposed research in this application will investigate postoperative cognitive function, pain index, inflammatory response, and oxidative stress effects of propofol versus sevoflurane anesthetic drugs in patients undergoing…
- Trial name
- NCT05289349
- Testing
- Propofol, Sevoflurane
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Rehab Werida
Microcirculation, Anesthetic Complication Spinal
Effect of Anesthetics on Microcirculation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
Volatile anesthetics, such as sevoflurane and desflurane, are commonly used in patients undergoing cardiac surgeries including off-pump coronary artery bypass.
- Trial name
- NCT03209193
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Breast Cancer
Evaluation of Impact of Nitrous Oxide on PONV in Breast Surgeries
Postoperative nausea and vomiting (PONV) is considered one of the most unpleasant postoperative discomforts and lead to serious complications of aspiration of gastric contents, suture dehiscence, esophageal rupture, subcutaneous…
- Trial name
- NCT02736604
- Testing
- nitrous oxide anesthesia, air anesthesia, laryngeal mask airway (LMA Supreme Size 3/4
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Tata Memorial Hospital
Acute Myocardial Infarction
Sevoflurane In Acute Myocardial Infarction
Ischemic postconditioning can reduce myocardial injury following myocardial infarction. A potential pharmacological agent is the anesthetic Sevoflurane.
- Trial name
- SIAMI (NCT00971607)
- Testing
- Oxygen + Sevoflurane
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Inflammation
Inflammation After One Lung Ventilation
The aim of the study was to prospectively investigate the influence of one-lung ventilation (OLV) on the inflammatory response and to identify possible antiinflammatory effects of the volatile anaesthetic sevoflurane.
- Trial name
- NCT02188407
- Testing
- Sevoflurane, Propofol
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
Pain, Postoperative, Phimosis
Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT02973958
- Testing
- Bupivacaine, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Elective Laparoscopic Surgery
Compare Pharmaceutical Economics and Efficacy of Sevoflurane With Low Fresh Gas Flow Balanced Anesthesia, Propofol Target Controlled Infusion Anesthesia and Propofol Induction Sevoflurane Maintenance Anesthesia
This study is being performed to compare the cost of anesthetic techniques with sevoflurane (low fresh gas flow balanced anesthesia) versus propofol (target controlled infusion [TCI]) versus propofol induction and sevoflurane…
- Trial name
- NCT01191476
- Testing
- Sevoflurane Inhalational Induction and Maintenance, Propofol Target Controlled Infusion for Induction and Maintenance, Propofol Target Controlled Infusion for Induction and Sevoflurane Inhalation for Maintenance
- Where
- 4 sites in China
- Volunteers
- 336 people
- Sponsor
- Abbott
Thoracic Surgery, Analgesics, Opioid
Opioid Free Anesthesia in Thoracic Surgery
Proper assessment of pain and adequate analgesia in thoracic surgery is a challenging issue for medical practitioners. Basic aspects of thoracic anaesthesia are general anesthesia, intubation with double lumen tube and separation…
- Conditions
- Thoracic Surgery, Analgesics, Opioid, Anesthesia, Conduction
- Trial name
- NCT04355468
- Testing
- Opioid Anesthesia, Opioid Free Anaesthesia
- Where
- Poland
- Volunteers
- 66 people
- Sponsor
- Medical University of Silesia
Adenotonsillectomy, Postoperative Pain
Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children
The purpose of this study is to determine the incidence of pain, emergence delirium and the combination of those postoperative negative behaviours during the first 15 minutes after awakening from sevoflurane anesthesia in…
- Conditions
- Adenotonsillectomy, Postoperative Pain, Emergence Delirium
- Trial name
- e-PONB ENT (NCT01096797)
- Testing
- Sevoflurane
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- San Gerardo Hospital
Patients Who Needs Sedation After Head & Neck Surgery
The Optimal Dose of Sevoflurane Via Anaconda® in Post-operative Patient Underwent Head & Neck Surgery
Sedation in the ICUs is very common. There is no ideal sedative yet, so research has been conducted to replace propofol and midazolam, which are the most commonly used sedatives in ICUs, by inhalation anesthetics.
- Trial name
- NCT03559920
- Testing
- Sedate using sevoflurane via anesthetic conserving device(ACD, Anaconda®) after surgery, Sedate using propofol.
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Yonsei University
Ambulatory Surgery, Anesthesia
Effects of Propofol on Early Recovery of Hunger After Surgery
Recovery of hunger is a source of comfort for patients after general anesthesia. Moreover, this aspect of post-operative period is often required for discharging patients from hospital after ambulatory surgery.
- Conditions
- Ambulatory Surgery, Anesthesia, Energy Expenditure, Food Intake
- Trial name
- Propo-Faim (NCT02272166)
- Testing
- propofol, Sevoflurane
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Rouen
Hyperglycemia
Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins
Anesthetic preconditioning (APC, a brief exposure to an anesthetic gas) has become an area of intense research interest because of its ability to protect tissue and organs from injury resulting from a cessation of blood flow and…
- Trial name
- NCT00995670
- Testing
- 5% dextrose, Vitamin C, Simvastatin
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Muscle Relaxation
Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum.
The objective of this study is to compare the value of deep neuromuscular block (NMB) (using rocuronium) in laparoscopy versus high dose opioids (using remifentanil) or 1 minimum alveolar concentration (MAC) inhalation (using…
- Trial name
- TIVA (NCT01930747)
- Testing
- rocuronium, Sevoflurane, remifentanyl
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- AZ Sint-Jan AV
Breast Cancer, Colo-rectal Cancer
Cancer Mortality Affected by the Choice of Anesthetic Drugs?
Knowledge gap: Does the choice of anaesthetic affect outcome for cancer surgery? Aim: To retrospectively examine possible associations (Cox Multiple Regression) between survival from breast-, colorectal-, or skin cancer and the…
- Conditions
- Breast Cancer, Colo-rectal Cancer, Skin Cancer
- Trial name
- NCT01418326
- Where
- Sweden
- Volunteers
- 3,284 people
- Sponsor
- Enlund
Pediatric
Effects of Chloral Hydrate on Induction, Maintenance, and Recovery From Sevoflurane Anesthesia in Day-case Pediatric Surgery
Effects of Choral Hydrate on Induction, Maintenance, and Recovery from Sevoflurane Anesthesia in Day-case Pediatric Surgery
- Trial name
- NCT01149226
- Testing
- chloral hydrate
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Hypoxic Pulmonary Vasoconstriction, Hypoxemia
Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2
Summary Currently, the COVID-19 pandemic has overtaken health systems worldwide, exceeding the capacity of intensive care units.
- Conditions
- Hypoxic Pulmonary Vasoconstriction, Hypoxemia, Acute Respiratory Distress Syndrome, SARS-CoV-2 Acute Respiratory Disease
- Trial name
- COVID-19 (NCT04998253)
- Testing
- Effects in oxygenation and hypoxic pulmonary vasoconstriction
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unidad Temporal COVID-19 en Centro Citibanamex
Anaesthesia, Surgery
Comparison of Two Electroencephalogram (EEG)-Derived Indices With Electroencephalogram Signals
Bispectral Index (BIS) and Entropy indices will be compared with each other, and to raw EEG signals in patients receiving sevoflurane anaesthesia.
- Trial name
- NCT01077674
- Where
- Finland
- Volunteers
- 65 people
- Sponsor
- Arvi Yli-Hankala
Squint
Lidocaine Gel 2% and Muscle Traction Pain During Squint Surgery in Pediatrics
Assessing the efficacy of lidocaine gel 2% application 10 minutes before surgery on post operative pain and the use of analgesics postoperatively
- Trial name
- NCT04859062
- Testing
- lidocaine gel 2%, control group
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Institute of Ophthalmology, Egypt
Anesthesia, Tolerance
Tolerance to Sevoflurane in Children Undergoing Repeated Drug Exposure
Deep sedation or general anesthesia is frequently required for infant that need radiotherapy to treat malignancies. As radiation therapy usually consist of several sessions, these patients are exposure to several consecutive…
- Trial name
- NCT04188782
- Testing
- Sevoflurane
- Where
- 2 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Anesthesia
Bispectral Index and End-Tidal Anesthetic Gas Concentration in Pediatric Patients
The purpose of this study is to investigate the relationship between BIS™ values including EEG profile and anesthetic agents in the pediatric population
- Trial name
- BTIGER (NCT04810481)
- Testing
- BIS Complete Monitoring System
- Where
- 8 sites in United States
- Volunteers
- 209 people
- Sponsor
- Medtronic - MITG