Clinical trials: Sevoflurane, completed
Anesthesia
Opioid-Free Anesthesia in Cardiac Surgery
The use of morphine derivatives is widespread for performing general anesthesia. However, opioids have their own side effects: respiratory depression, digestive ileus, cognitive dysfunction, postoperative hyperalgesia…
- Trial name
- OFACS (NCT04940689)
- Testing
- Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg, Remifentanil
- Where
- 5 sites in France
- Volunteers
- 268 people
- Sponsor
- University Hospital, Rouen
Colon Cancer
Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Colon Cancer
Anesthetics agents has variety inflammation during the cancer surgery. This perioperative inflammation can influence to cancer metastasis or recurrence.
- Trial name
- NCT02567942
- Testing
- propofol group, sevoflurane group
- Where
- South Korea
- Volunteers
- 153 people
- Sponsor
- Konkuk University Medical Center
Renal Failure
Desflurane vs. Sevoflurane in Endovascular Aortic Repair
Randomized Clinical Trial following the evaluation of the impact on renal function in patients undergoing endovascular aortic aneurysm repair with two anesthetics protocols (Desflurane versus Sevoflurane) on the first 24 hours…
- Trial name
- NCT03917186
- Testing
- Sevoflurane, Desflurane
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Begoña Quintana Villamandos
Requiring Sedation by Sevoflurane in ICU, Adult Patients
Evaluation of Richmond Agitation Sedation Scale According to Alveolar Concentration of Sevoflurane During a Sedation With Sevoflurane in ICU Patients
Describe the Richmond Agitation Sedation Scale (RASS) values corresponding to the values of Minimum alveolar concentration of sevoflurane during sedation of patients in ICU
- Conditions
- Requiring Sedation by Sevoflurane in ICU, Adult Patients, Patients Covered by French Health Care System, Patients Who Have Given Their Consent
- Trial name
- SEVORASS (NCT02202720)
- Testing
- Sevoflurane
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate (TURP)
Spinal Versus General Anesthesia on Coagulation and Fibrinolysis During Transurethral Resection of the Prostate
This prospective randomized clinical trial aims to compare the effects of spinal and general anesthesia on perioperative coagulation and fibrinolysis in patients undergoing elective transurethral resection of the prostate (TURP).
- Trial name
- NCT07734233
- Testing
- Spinal Anesthesia (bupivacaine), General Anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Haseki Training and Research Hospital
Anesthesia, Children, Only
Sevoflurane and Laryngeal Mask Airway Versus Propofol Infusion and Facemask for EUA in Children
The goal of this clinical trial is to find out the optimal technique of anesthesia for eye examination in children. The main question it aims to answer is: Is propofol infusion and simple oxygen facemask associated with earlier…
- Trial name
- NCT06656455
- Testing
- sevoflurane via LMA, Propofol with oxygen via simple mask
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
General Anesthesia
Effect of Sevoflurane and Propofol on Hepato-splanchnic Pressure and Flow During Hepatobiliary Surgery
Blood loss in hepatobiliary surgery is correlated with an increase in postoperative complications (e.g. transfusion related lung injury and tumor recurrence) and reduced longterm survival.
- Trial name
- NCT03772106
- Testing
- Propofol Fresenius, sevorane
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- University Hospital, Ghent
Analgesic Adverse Reaction, Nociceptive Pain
The Correlation Between Sevoflurane and qNOX
This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.
- Conditions
- Analgesic Adverse Reaction, Nociceptive Pain, Inhalation; Vapor
- Trial name
- NCT03665792
- Testing
- nociception index qNOX
- Where
- China
- Volunteers
- 58 people
- Sponsor
- China International Neuroscience Institution
Ultrasound Guided Block, Pediatric Surgery
Mid-transverse Process to Pleura Block in Pediatric Thoracotomy
The aim of this study is to assess the effectiveness of analgesia of US guided MTP block in pediatrics undergoing thoracotomy.
- Conditions
- Ultrasound Guided Block, Pediatric Surgery, Analgesia
- Trial name
- NCT05999734
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Intraoral Tumor
Differences in Speed of Recovery From Anesthesia for Intraoral Surgery
The goal of this clinical trial is to compare two groups of patients going in general anesthesia for intraoral surgery, the first group TIVA with propofol and the second group inhalational with sevoflurane.
- Trial name
- PSIOS (NCT06275087)
- Testing
- Propofol, Sevoflurane
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Clinical Hospital Centre Zagreb
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Ear Throat Nose Surgery, Delirium - Postoperative
The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
Delirium is a postoperative complication that hinders a child's recovery and presents challenges in assessment and management. Ear nose throat (ENT) procedures have been suggested as a risk factor for delirium[1].
- Conditions
- Ear Throat Nose Surgery, Delirium - Postoperative, Pain Postoperative
- Trial name
- NCT07191652
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul University - Cerrahpasa
Brain Damage, Postoperative
Evaluation of Neuronal Damage in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy With Biomarkers
Robotic assisted laparoscopic surgery has become an alternative to open or laparoscopic technique in various surgical fields. Robot assisted laparoscopic surgery is preferred by surgeons and patients due to easy accessibility…
- Conditions
- Brain Damage, Postoperative, Surgery-Complications
- Trial name
- NCT05692804
- Testing
- Mini Mental State Examination(MMSE),Montreal Cognitive Assessment ( MoCA),S100B ( protein S100 subunit beta) ,GFAP ( glial fibrillary acidic protein ),NSE ( neuron-specific enolase )
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Delirium
Hip Fracture Surgery in Elderly Patients
The objective of this study is to evaluate the incidence of Post-Operative Delirium (POD), diagnosed with the Confusion Assessment Method (CAM), in elderly patients undergoing hip fracture surgery under general anaesthesia with…
- Trial name
- HIPELD (NCT01199276)
- Testing
- Xenon, Sevoflurane
- Where
- 13 sites in Belgium, France and 4 more
- Volunteers
- 256 people
- Sponsor
- Air Liquide Santé International
Cancer of Liver, Cancer of Pancreas
Effects of Dexmedetomidine During IRE Procedures for Solid Tumours
The purpose of the study is to evaluate effects of dexmedetomidine on anaesthesia during IRE procedures for solid tumours
- Trial name
- NCT02044224
- Testing
- Dexmedetomidine
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University Hospital
Vocal Cord; Injury, Superficial
Laryngeal Injuries After Removal of the Tracheal Tube: A Comparison Between Sevoflurane and Propofol
Vocal cord injuries occur not only during tracheal intubation, but also during surgery and during removal of tracheal tube. Volatile anesthetics increase neuromuscular block of muscle relaxants.
- Trial name
- NCT01616966
- Testing
- Sevoflurane, propofol
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University of Rostock
Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement
Effects of Bolus Versus Infusion Ketamine During Laparoscopic Cholecystectomy
This prospective, randomized, controlled study evaluated the effects of different ketamine administration strategies in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement, Ketamine, Postoperative Pain
- Trial name
- ketamine (NCT07900854)
- Testing
- ketamine bolus, ketamin infusion, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Atelectasis
Continuous Positive Airway Pressure Decreased Lung Collapse During General Anesthesia Induction in Pediatric Patients
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT03461770
- Testing
- CPAP
- Where
- Argentina
- Volunteers
- 42 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Gynecological Surgery
Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence
Enhanced recovery after surgery (ERAS) protocols are being explored to improve patient outcomes. The method of inducing anesthesia and maintenance using inhalation anesthetics is common but may delay recovery.
- Trial name
- NCT06385002
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Drug Usage
Remifentanil for Smooth Emergence in Elderly Patients
Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anaesthetic drugs than younger patients.
- Trial name
- NCT02334046
- Testing
- Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Ajou University School of Medicine