Clinical trials: Sevoflurane, completed
Postoperative Pain
Comparison Sacral Erector Spinae Block Versus Caudal Block
The purpose of this research study is to find the best way to decrease pain in children whom have had hypospadias surgery. Investigators will perform two technique; Caudal block or Sacral erector spinae block.
- Trial name
- NCT04106687
- Testing
- Ultrasound Guided Caudal Block, Sacral Erector Spinae Block
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Ear Throat Nose Surgery, Delirium - Postoperative
The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
Delirium is a postoperative complication that hinders a child's recovery and presents challenges in assessment and management. Ear nose throat (ENT) procedures have been suggested as a risk factor for delirium[1].
- Conditions
- Ear Throat Nose Surgery, Delirium - Postoperative, Pain Postoperative
- Trial name
- NCT07191652
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul University - Cerrahpasa
Obesity, Anesthesia
Optimal Anesthesia for Morbidly Obese Patients
Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia.
- Trial name
- NCT04395248
- Testing
- Exploring potential risk factors of difficult intubation using ultrasound, Radial artery catheterization using ultrasound guidance or blind palpation, Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Sleep Disturbance, Anesthesia; Adverse Effect
Effects of Anesthetics and Surgery on Sleep Quality in Patients Undergoing Posterior Spinal Instrumentation Surgery
Investigators aimed to evaluate the impact of the anesthesia method and surgical procedure on the sleep patterns and sleep quality of patients undergoing posterior spinal instrumentation using the Pittsburgh Insomnia Rating…
- Trial name
- NCT06523881
- Testing
- Sevoflurane (Sevorane® liquid 100%, Abbvie Pharmaceuticals, Istanbul, Turkey), Propofol (Propofol-PF® 1% (Polifarma Pharmaceuticals, Tekirdag, Turkey)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uludag University
Coronary Disease, Coronary Artery Disease
MACBIS50 in Patients Undergoing CAG During Normothermic CPB Phase.
Background: We determined the minimum alveolar concentration (MAC) of sevoflurane for maintaining bispectral index (BIS) below 50 (MACBIS50) in patients undergoing coronary artery bypass grafting during normothermic…
- Trial name
- NCT02711384
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Pain, Monitoring, Intraoperative
Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial
After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively in infants, children and adolescents.
- Trial name
- Pain@OR-kids (NCT03449732)
- Testing
- PDR measurement
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Delirium on Emergence
Post Extubation Delirium and End-tidal Sevoflurane Concentration
The purpose of this study is to determine whether the incidence of emergence delirium will be reduced when end-tidal concentration of sevoflurane decreases.
- Trial name
- NCT02489734
- Testing
- sevoflurane
- Volunteers
- 109 people
- Sponsor
- Children's Hospital of Fudan University
Pharmacokinetics of Inhaled Anesthetics
Ventilatory Effect on Speed of Anesthesia Under Various Inhaled Anesthetics
Three groups of patients are going to have minor surgery under general anesthesia with inhaled anesthetics and different ventilatory setting (Tidal volume: 8, 10, 12 ml/kg, respiratory rate: 10/min each).
- Trial name
- NCT01171833
- Testing
- Sevoflurane, Desflurane, Isoflurane
- Volunteers
- 36 people
- Sponsor
- DongGuk University
Condition / Focus: Postoperative Cognitive Dysfunction (POCD) Following Spinal Surgery
COMPARISON OF SEVOFLURANE AND PROPOFOL ADMINISTRATION ON POSTOPERATIVE COGNITIVE DYSFUNCTION IN SPINAL SURGERY USING THE MINI-MENTAL STATE EXAMINATION (MMSE)
This study aims to compare the effects of two commonly used anesthetic agents, sevoflurane and propofol, on cognitive function after spinal surgery.
- Trial name
- SEVO-PROP-MMSE (NCT07378878)
- Testing
- Sevoflurane Administration, Propofol Administration
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Sumatera Utara
Anesthesia
Improving Information Extraction From EEG on Cerebral Anesthetic Drug Effects
This is an interventional, randomized controlled study in health volunteers that involves collecting data on raw EEG waves measuring various combinations of anesthetic drugs during standardized drug titration.
- Trial name
- NCT02043938
- Testing
- SedLine EEG sensor
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Congenital Heart Disease
Remote Preconditioning and Myocardial Protection
Remote ischemic preconditioning (RIPC) of the myocardium by limb ischemia/reperfusion may mitigate cardiac damage, but its interaction with the anesthetic regimen is unknown.
- Trial name
- NCT02877238
- Testing
- Sevoflurane plus remote ischemic preconditioning, Total intravenous anesthesia plus remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Assiut University
Anesthesia
Comparison of Analgesic Effect of Volatile Anesthetics
The purpose of this clinical trial is to compare analgesic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using surgical pleth index.
- Trial name
- NCT02830243
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Breast Cancer
Anesthetic Effect on Immune Cell in Patients With Cancer
Anesthetics agents has an effect on immune response during the cancer surgery.This influence can regulatory to immune activity or cancer cell survival.
- Trial name
- NCT02758249
- Testing
- Sevoflurane, propofol
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Konkuk University Medical Center
Postoperative Complications, Hip Fracture
A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia
This pilot project will address the gaps in knowledge regarding the effect of anesthetic technique on the risk of delirium through an adequately-powered trial employing standardized regimens for treatment and outcome assessment…
- Conditions
- Postoperative Complications, Hip Fracture, Delirium
- Trial name
- NCT02190903
- Testing
- General endotracheal anesthesia, Regional (spinal) Anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Intracranial Pressure Change, Optic Nerve Diameter
VIMA vs TIVA and ONSD in Laparoscopic Cholecystectomy
This study compared two commonly used general anesthesia techniques in adults undergoing elective laparoscopic gallbladder surgery.
- Trial name
- NCT07786740
- Testing
- Propofol (Astra-Zeneca), Remifentanil, Sevofluorane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bagcilar Training and Research Hospital
Colorectal Cancer (CRC), Sarcopenia
TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery
This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer.
- Trial name
- TIVABAL-CRC (NCT07237438)
- Testing
- total intravenous anaesthesia, sevoflurane anaesthesia
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Hemodynamic Stability, Pulmonary Diseases or Conditions
A Study Comparing Sevoflurane and Propofol in Patients Undergoing Endobronchial Ultrasound Guided Needle Aspiration
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used to obtain samples from mediastinal and hilar lymph nodes or lung parenchymal lesions for diagnostic and staging…
- Conditions
- Hemodynamic Stability, Pulmonary Diseases or Conditions, Complication of Anesthesia
- Trial name
- NCT07338578
- Testing
- propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi
Neuromuscular Blockade
Comparing Reversal With Neostigmine and Sugammadex in Paediatric
A reversal agent is commonly given to improve neuromuscular function after intra-operative administration of non-depolarizing neuromuscular blocking agents.
- Trial name
- JS (NCT03137290)
- Testing
- Neostigmine, Sugammadex Sodium
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- Universiti Sains Malaysia
Anesthesia, Exhaled Nitric Oxide
Effect of Type of General Anesthesia Maintenance on Exhaled Nitric Oxide and Eosinophil Blood Count
Nitric oxide (NO) is a free radical in gas state which plays an important role in a variety of processes relevant to respiratory physiology.
- Conditions
- Anesthesia, Exhaled Nitric Oxide, Eosinophil Blood Count
- Trial name
- NCT02065635
- Testing
- maintenance with sevoflurane, maintenance with propofol
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Breast Cancer
The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC)
Because neoplastic disease is one of the leading causes of death worldwide and breast cancer is one of the most frequent neoplasia among women, the possibility of influencing the evolution of patients starting from the moment of…
- Trial name
- TIVA/TCI-BC (NCT02839668)
- Testing
- Lidocaine, Sevoflurane, TIVA-TCI
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy