Clinical trials: Sevoflurane, completed
Emergence Agitation
Sevoflurane Induced Emergence Agitation
Investigators evaluated the effect of intranasal ketamine or alfentanil addition to oral midazolam for prevention of emergence agitation.Seventy-eight, 1-8 year-old children, undergoing urological surgery with sevoflurane…
- Trial name
- NCT02022488
- Testing
- midazolam, alfentanil, ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Yeditepe University Hospital
Emergence Agitation, Septoplasty Surgeries
The Effects of Three Different Anesthetic Methods on Postoperative Agitation
Adult patients undergoing septoplasty surgery will be evaluated in this study. The three different anesthesia methods used will be examined for psotoperative agitation: Total intravenous anesthesia (TIVA), Combined anesthesia…
- Trial name
- NCT07304206
- Testing
- SEVOFLURANE, TIVA, CIVIA
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Inonu University
Kidney Donation/Transplantation
"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail
To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients…
- Trial name
- NCT01248871
- Testing
- procedure:sevoflurane-remifentanil/sufentanil, volatile agent only during reperfusion, propofol-remifentanil/sufentanil
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- University Medical Center Groningen
Post-Operative Pain
Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery
The anti-epileptic drugs such as gabapentin and other non-steroidal anti-inflammatory drugs (NSAID) such as celecoxib were used as a part of multimodal analgesia to control such pain.
- Trial name
- NCT04342065
- Testing
- Celecoxib capsules, Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Egypt Cancer Institute
Hepatectomy
Effect of Epidural Anesthesia and Analgesia on Patients' Outcomes After Liver Resection
The purpose of this study is to analyze the effects of epidural anesthesia and analgesia on intraoperative clinical outcome, postoperative recovery, metabolic changes, and immune functions of the patients receiving open liver…
- Trial name
- NCT01617811
- Testing
- epidural anesthesia and analgesia
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Sir Run Run Shaw Hospital
Postoperative Cognitive Dysfunction
The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients
The goal of this clinical trial is to compare the permeability of blood-brain barrier between the intravenous anesthesia group and the inhalation gas anesthesia group in the elderly patients undergoing surgery.
- Trial name
- NCT06353516
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Oxygenation, Spinal Surgery
Effects of Different Anesthetic Gases on Hemodynamics, Arterial Oxygenation and Pulmonary Mechanics
The bronchodilator effects of volatile anesthetics have been the subject of many clinical studies. It is known that all volatile anesthetics, especially halothane, have similar effects.
- Conditions
- Oxygenation, Spinal Surgery, Sevoflurane, Desflurane
- Trial name
- NCT06118489
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Vocal Cord; Injury, Superficial
Laryngeal Injuries After Removal of the Tracheal Tube: A Comparison Between Sevoflurane and Propofol
Vocal cord injuries occur not only during tracheal intubation, but also during surgery and during removal of tracheal tube. Volatile anesthetics increase neuromuscular block of muscle relaxants.
- Trial name
- NCT01616966
- Testing
- Sevoflurane, propofol
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University of Rostock
Opioid-Related Disorders, Substance-Related Disorders
Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14
The purpose of this study is to determine the effects of combined sevoflurane and nitrous oxide inhalation on mood, psychomotor performance, and the pain response in humans.
- Trial name
- NCT00000262
- Testing
- 30% Nitrous oxide, 0.4% Sevoflurane, 0.2% sevoflurane
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Endoplasmic Reticulum Stress
Effect of Anaesthesia on ER Stress in Cancer Patients
Investigate the change in endoplasmic reticulum stress after cancer surgery according to different anaesthetics including propofol and sevoflurane.
- Trial name
- NCT03561831
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Konkuk University Medical Center
Sevoflurane
Sevoflurane-remifentanil EC50 (The 50% Effective Concentration) Values for LMA-Supreme Versus LMA ProSeal Insertion
The study was designed to determine and compare the sevoflurane EC50 optimal concentration for laryngeal mask airway Supreme versus laryngeal mask airway ProSeal insertion during target-controlled infusion of remifentanil.
- Trial name
- NCT03003377
- Testing
- laryngeal mask supreme, laryngeal mask proseal
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Airway Obstruction
Effect of Laryngeal Mask Airway on Image Quality n Pediatric Patients Undergoing Magnetic Resonant Imaging
This study compare the effects of Oral airway vs LMA in preventing anesthesia-induced partial airway obstruction, in an attempt to lessen MRI motion artifacts, which would result in improvements in image quality.
- Trial name
- NCT04730362
- Testing
- guedel airway, supraglottic airway, propofol bolus and then anesthesia sevoflurane
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Egypt
Thyroidectomy
The Effect of Preoperative Anxiety Level on the Induction Dose of Propofol and Minimum Alveolar Concentration (MAC) Hour of Sevoflurane During Thyroidectomy
This study is to evaluate the level of anxiety, and to check the correlation of induction dose and the amount of sevoflurane to keep anesthetic depth in in female patients undergoing thyroidectomy.
- Trial name
- NCT01149239
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Analgesia
Confirmatory Study of HFVI Guided Analgesic Administration in Surgical Subjects
The current study is intended to be a prospective clinical performance validation study designed to confirm the clinical utility of HFVI-guided fentanyl administration during sevoflurane anesthesia.
- Trial name
- NCT04049656
- Testing
- HFVI
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Florida
Abdominal Hysterectomy, General Anesthesia
Intravenous Administration of Magnesium Sulfate in Hysterectomy Cases
In our study, it was aimed to show the contribution of intraoperative intravenous magnesium sulfate administration to peroperative opioid consumption and postoperative analgesia.
- Conditions
- Abdominal Hysterectomy, General Anesthesia, Magnesium Sulfate
- Trial name
- NCT05644873
- Testing
- magnesium sulfate group, control group saline
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Anesthesia
Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)
The purpose of this study is to compare the infusion rate of Org 9426 following intubating dose of Org 9426 0.6 mg/kg or 0.9 mg/kg in adult surgical patients.
- Trial name
- NCT00988520
- Testing
- Rocuronium bromide, Sevoflurane, Propofol
- Volunteers
- 38 people
- Sponsor
- Merck Sharp & Dohme LLC
Thyroid Neoplasm
Comparison Between Remifentanil Target-controlled Infusion and Dexmedetomidine Bolus Administration for Smooth Emergence From General Sevoflurane Anesthesia
Remifentanil target-controlled infusion and dexmedetomidine single-dose administration are known to reduce airway response and haemodynamic stimulation during anaesthetic recovery.
- Trial name
- NCT01617694
- Testing
- dexmedetomidine, Normal Saline
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Yonsei University
Agitation
Scalp Nerve Block on Emergence Agitation
Emergence agitation is a common problem in children during recovery from sevoflurane anesthesia. Pain is considered as a cause of postoperative emergence agitation and compounding factor of agitation assessment in children.
- Trial name
- NCT02428283
- Testing
- Ropivacaine, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Ajou University School of Medicine
Pediatric ALL, Pediatric Anesthesia
Nalbuphine Versus Ketamine for Prevention of Emergence Agitation After Sevoflurane in Children Undergoing Tonsillectomy
The effect of low dose nalbuphine or ketamine in the prevention of emergence agitation after sevoflurane anesthesia in children undergoing tonsillectomy with or without adenoidectomy.
- Trial name
- NCT05176119
- Testing
- Nalbuphine Injection, Ketamine, Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Head and Neck Neoplasms, Oncologic Patients
Pharmacotherapy Personalization of Cancer Patients
Treatment personalization could ensure better outcome than standard procedures. It is particularly important in intensive care units where patients received many drugs and procedures. Their health status can change very fast.
- Trial name
- NCT04866498
- Testing
- Infusion Intravenous
- Where
- 2 sites in Poland
- Volunteers
- 22 people
- Sponsor
- Poznan University of Medical Sciences