Clinical trials: Sevoflurane, completed
Anesthesia
Evaluation of the Concentration-prediction for Oxygen and Volatile Anesthetic Agents in the 'Draeger Perseus A500' Anesthesia Machine
The anesthesia machine "Draeger Perseus A 500" has an integrated software which calculates the predicted course of the concentration of oxygen and the volatile anesthetics sevoflurane and desflurane for the next 20 minutes.
- Trial name
- NCT03465319
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Anesthesia, General
The Ratio of Hypnotic to Analgesic Potency of Volatile Anesthetics
The aim of this clinical trial is to evaluate the ratio of hypnotic to analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using SPI and EEG analysis.
- Trial name
- NCT02698514
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Anesthesia
Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance
During this study, the pharmacodynamic interactions between sevoflurane and remifentanil will be studied.
- Trial name
- NCT00522587
- Testing
- Fixed sevoflurane dose 1, Fixed sevoflurane dose 2, Fixed sevoflurane dose 3
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Arthroplasty, Replacement, Hip, Knee
Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty
As the world goes into the aging society, the number of total hip and total knee arthroplasty (THA and TKA) will increase fast. It's important to develop strategies to improve the quality of healthcare and get earlier recovery…
- Trial name
- NCT03517098
- Testing
- The ERAS group, The non-ERAS group
- Where
- China
- Volunteers
- 640 people
- Sponsor
- West China Hospital
Analgesia, Anesthesia
Analgesic Depth Evaluation During General Anesthesia With Dexmedetomidine-remifentanil Infusion. A Pilot Study
The aim of this study is to verify the feasibility of an evaluation of the depth of analgesia during an opioid sparing anesthesia (OSA) carried out with continuous infusion of dexmedetomidine in addition to general multimodal…
- Trial name
- NCT05785273
- Testing
- Pupillometer
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Università degli Studi di Brescia
Airway Reflexes, Protective, Recovery After Neuromuscular Block
Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Protective airway reflexes may be impaired in the postoperative period, creating the potential for aspiration of gastric contents, even after a patient exhibits appropriate response to command.
- Conditions
- Airway Reflexes, Protective, Recovery After Neuromuscular Block, Anesthetic Recovery
- Trial name
- NCT01199237
- Testing
- Sevoflurane, Desflurane, Rocuronium
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
Intraocular Pressure, Anesthesia
Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardiopulmonary Bypass
The aim of the study to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia on intraocular pressure (IOP) during coronary artery bypass graft surgery (CABG) with cardiopulmonary…
- Trial name
- NCT06494969
- Testing
- Intraocular pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Antalya Training and Research Hospital
Neuromuscular Monitoring
Rocuronium Consumption in Etomidate-based and Propofol-based General Anesthesia Under Sevoflurane
Different concentration of sevoflurane was given to maintain anesthesia. The dose of propofol to maintain BIS between 40-60 and the consumption of rocuronium was recorded and evaluated.
- Trial name
- NCT02711917
- Testing
- MAC 0.5, MAC 0.75, MAC 1.0
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
AKI - Acute Kidney Injury
Sevoflurane and Dexmedetomidine's Contrasting Renal Impacts After Non-Cardiac Surgery
Postoperative acute kidney injury (PO-AKI) is a significant complication, especially after complex surgeries. The choice of anesthetic may influence PO-AKI risk.
- Trial name
- NCT06835010
- Testing
- Dexmedetomidine, Sevoflurane inhalant product
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Acute Pain, Chronic Pain
Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
Research suggests that the type of anesthesia used for surgery may affect intraoperative stress hormone levels. There is also data to support that an increased level of stress hormones leads to increased pain after surgery.
- Conditions
- Acute Pain, Chronic Pain, Hernia, Anesthesia, Intravenous
- Trial name
- NCT02527083
- Testing
- Propofol, Sevoflurane, Remifentanil
- Volunteers
- 10 people
- Sponsor
- VA Pittsburgh Healthcare System
Ischemic Heart Disease
Sevoflurane Effect on Left Atrial Performance: A Transoesophageal Echocardiographic Study
The left atrial performance is affected by the preload as well as the afterload. The LA active pumping is increased by stretching of the LA but within limits, after which the active pumping declines.
- Trial name
- NCT03999463
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Reperfusion Injury
Role of Volatile Anesthetics for Hepatic Protection
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of…
- Trial name
- NCT00516711
- Testing
- Sevoflurane
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Zurich
Elective Major Abdominal Surgery
Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries
Acute postoperative pain is an important issue after major abdominal surgeries for which different analgesic modalities have been tried.
- Trial name
- NCT04541732
- Testing
- Thoracic epidural block, Ultrasound-guided bilateral quadratus lumborum block, Induction of general anaesthesia with propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Emergence Agitation
Transition to Propofol After Sevoflurane Anaesthesia to Prevent Emergence Agitation
The aim of this randomized double-blinded study is to determine whether transition to propofol for 3 min at the end of sevoflurane anaesthesia reduces the incidence of EA in children undergoing genito-urinary paediatric surgeries.
- Trial name
- NCT03179293
- Testing
- Propofol, Normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Anesthesia
Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics
congenital hearts are very sensitive and irritable to deal with, especially during repair defects, the child's heart is exposed to impaired myocardial function during the entire procedure.
- Trial name
- NCT05314569
- Testing
- Ketamine- dexmedetomidine, Fentanyl- midazolam, Isoflurane
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Cairo University
Children, Urologic Diseases
Emergence Agitation Between Sevoflurane and Desflurane in Pediatric
Sevoflurane is the volatile anesthetic agent of choice in pediatric surgery. Nevertheless, sevoflurane anesthesia had the high incidence of emergence delirium compared to halothane and isoflurane.Bortone L et al.reported…
- Conditions
- Children, Urologic Diseases, Ambulation Difficulty
- Trial name
- NCT01235143
- Testing
- Desflurane, Sevoflurane
- Where
- Thailand
- Volunteers
- 136 people
- Sponsor
- Prince of Songkla University
Nociceptive Pain, Anesthesia
NOL Index to Compare the Intraoperative Analgesic Effect of Propofol Versus Sevoflurane
The purpose of this prospective randomized controlled study is to compare the analgesic properties of propofol and sevoflurane using variation of the NOL index and standard monitoring (Heart Rate and Mean Arterial Blood Pressure)…
- Trial name
- PROSEVNOL (NCT04567160)
- Testing
- Propofol, Sevoflurane
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
ESPB, Mg Sulfate,Post Mastectomy
Efficacy of Magnesium Sulfate as an Adjuvant in Erector Spinae Plane Block as an Anesthetic Post Operative After Modified Radical Mastectomy
efficacy of magnesium sulfate as an adjuvant in erector spinae plane block as an anesthetic post-operative after modified radical mastectomy
- Trial name
- NCT05976464
- Testing
- Magnesium sulfate in erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
CHD - Coronary Heart Disease
Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults
Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment.
- Trial name
- NCT05693428
- Testing
- Propofol, Isoflurane, Sevoflurane
- Where
- Kazakhstan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Astana Medical University
General Anesthetic Drug Adverse Reaction
Postoperative Effects of Propofol Versus Sevoflurane Anesthesia
Background: The choice of appropriate anesthetics is essential to protect brain function, decrease perioperative complications, and provide high-quality care, and better quality of life.
- Trial name
- NCT05935930
- Testing
- Propofol 10 MG/ML Injection, Sevoflurane Inhalation Liquid
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Damanhour Teaching Hospital