Clinical trials: Sevoflurane, completed
Microlaryngoscopy, Rigid Bronchoscopy
Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Use of Muscle relaxant and reversal with Sugammadex at end of airway procedures will reduce the time to extubation after end of procedure
- Trial name
- NCT03111121
- Testing
- Sugammadex, neostigmine, glycopyrrolate
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Postoperative Pain
Effects of TIVA With Propofol Versus Inhalational Anaesthesia on Postoperative Pain After Hepatectomy
Propofol is a commonly used intravenous anaesthetic drugs both for induction and maintenance of general anaesthesia. Advantages of total intravenous anaesthesia (TIVA) with propofol include reduced nausea and vomiting, reduced…
- Trial name
- NCT03597997
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in Hong Kong
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Anesthesia
Bispectral Index to Guide Intubation in Pediatric Anesthesia
This prospective study aimed to determine the minimal level of Bispectral index needed for quality laryngoscopy before ear, nose and throat surgery in children.
- Trial name
- NCT02806596
- Testing
- Sevoflurane
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege
Movement After Intravenous Cannulation
Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient
This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%
- Trial name
- NCT04284579
- Testing
- IV cannula
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Thoracic Surgery With One-lung Ventilation
One-lung Ventilation: Expression of Pulmonary Inflammatory Mediators
One-lung ventilation; organ protection; volatile anesthetics One-lung ventilation has become a common procedure for thoracoscopic surgery. Two hypothesis will be tested in this study: 1.
- Trial name
- NCT00515905
- Testing
- Sevoflurane/propofol
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
Uterus Myoma, Uterine Cancer
Effect of Anesthetic Agents on Optic Nerve Sheath Diameter
The present study is to evaluate the effect of anesthetic agents ( propofol , sevoflurane) on intracranial pressure of female patients undergoing laparoscopic-robotic surgery.
- Trial name
- NCT03701529
- Testing
- Sevoflurane, Propofol
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
General Anesthesia
Evaluation of the Analgesia Nociception Index With Varying Remifentanil Concentrations Under Sevoflurane
Analgesia Nociception Index（ANI）which is derived from heart rate variability can be used to detect noxious stimulation during propofol while changing remifentanil concentrations.
- Trial name
- NCT05063461
- Testing
- Tetanic stimulation, Skin incision
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Beijing Chao Yang Hospital
Down Syndrome
The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.
- Trial name
- NCT02971254
- Testing
- Sevoflurane, Desflurane
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- Asklepieion Voulas General Hospital
Anesthesia, General
The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval
The purpose of this study is to investigate effect of dexmedetomidine and tracheal intubation on heart rate variability and QTc interval.
- Trial name
- NCT01584570
- Testing
- 0.5 mcg/kg IV infusion for 10 min, 1.0 mcg/kg IV infusion for 10 min
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
ICU Patients With Indication of Sedation
A Pharmacokinetic Study of Sevoflurane Inhalation in Burn ICU Patients
Comparing a pharmacokinetic model of a short sevoflurane sedation in burn ICU patients with control ICU patients.
- Trial name
- SEVOBURN (NCT02048683)
- Testing
- Short term sedation with sevoflurane in ICU
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
The Absorption of Glycine in Operative Hysteroscopy
The Impact of Anesthesia on the Absorption of Glycine in Operative Hysteroscopy: a Randomized Controlled Trial
This study aimed to compare two types of anesthesia (general anesthesia and local anesthesia with sedation) on the absorption of glycine in operative hysteroscopy.
- Trial name
- NCT01124383
- Testing
- General anesthesia, Local anesthesia with sedation
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- CHU de Quebec-Universite Laval
Pain, Pain, Postoperative
Monitor-Guided Analgesia During General Anesthesia - Part I
This prospective randomized clinical trial evaluates the effects of a monitor-guided opioid analgesia during general anesthesia.
- Conditions
- Pain, Pain, Postoperative, Nociceptive Pain, Opioid Use
- Trial name
- MOGADA (NCT03303651)
- Testing
- Opioid administration in intervention groups, Opioid administration in control group
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Airway Obstruction
Effect of Laryngeal Mask Airway on Image Quality n Pediatric Patients Undergoing Magnetic Resonant Imaging
This study compare the effects of Oral airway vs LMA in preventing anesthesia-induced partial airway obstruction, in an attempt to lessen MRI motion artifacts, which would result in improvements in image quality.
- Trial name
- NCT04730362
- Testing
- guedel airway, supraglottic airway, propofol bolus and then anesthesia sevoflurane
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Egypt
Achalasia
Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy
This prospective observational study aims to investigate the association between the autonomic dysfunction and hemodynamic instability during per-oral endoscopic myotomy under general anesthesia in achalasia patients.
- Trial name
- NCT05772260
- Testing
- Per-oral endoscopic myotomy
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Gangnam Severance Hospital
Liver Cancer, Hepatectomy
Effects of Different Anesthetic Techniques on Intraoperative and Postoperative Pain Levels and Cognitive Function in Patients Undergoing Hepatectomy for Liver Cancer
To evaluate the effects of general anesthesia (GA) versus combined general and epidural anesthesia (GEA) on postoperative pain, cognitive dysfunction (POCD), hospital stay, and recovery quality in liver cancer patients undergoing…
- Conditions
- Liver Cancer, Hepatectomy, Anesthesia Techniques, Postoperative Pain
- Trial name
- NCT07097220
- Testing
- General Anesthesia (GA) group, General-Epidural Anesthesia (GEA) group
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Sir Run Run Shaw Hospital, Qingchun Campus, Zhejiang University School of Medicine,
Catheterization
Intravenous Cannulation In Children During Sevoflurane Induction
This interventional simple-blind,randomized trial has included 90 children of American Society of Anesthesiologist (ASA) physical status I or II aged between 1 to 12 years of either sex, scheduled for for outpatient minor surgery…
- Trial name
- NCT03254303
- Testing
- Difficulty of catheterization in group 60 s, Difficulty of catheterization in group 90 s, Difficulty of catheterization in group 120 s
- Volunteers
- 90 people
- Sponsor
- Leila mansali stambouli
Postoperative Complications, Hip Fracture
A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia
This pilot project will address the gaps in knowledge regarding the effect of anesthetic technique on the risk of delirium through an adequately-powered trial employing standardized regimens for treatment and outcome assessment…
- Conditions
- Postoperative Complications, Hip Fracture, Delirium
- Trial name
- NCT02190903
- Testing
- General endotracheal anesthesia, Regional (spinal) Anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Other Specified Injuries of Vocal Cord, Sequela
Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant)
Anesthesia induction and tracheal intubation can be performed with and without neuromuscular blocking agents (NMBAs). Tracheal intubation can be performed with sevoflurane instead of NMBAs; intubating conditions are similar and…
- Trial name
- SEVODosage (NCT01896245)
- Testing
- sevoflurane 1,0, sevoflurane 1,2, sevoflurane 1,4
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University of Rostock
Postoperative Cognitive Dysfunction
Early Postoperative Cognitive Dysfunction After Closed Loop Anesthesia vs Inhalational Anesthesia or TIVA
This study is designed to test the hypothesis that closed loop system reduces post operative cognitive dysfunction incidence 15 min after anesthesia more than desflurane, sevorane, total intravenous anesthesia manually guided by…
- Trial name
- NCT02656901
- Testing
- auto total endovenous anesthesia, Manual Desflurane anesthesia, Manual Sevoflurane anesthesia
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- University of Foggia
Post-Operative Pain
Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery
The anti-epileptic drugs such as gabapentin and other non-steroidal anti-inflammatory drugs (NSAID) such as celecoxib were used as a part of multimodal analgesia to control such pain.
- Trial name
- NCT04342065
- Testing
- Celecoxib capsules, Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Egypt Cancer Institute