Clinical trials: Sevoflurane, completed
Patients Who Needs Sedation After Head & Neck Surgery
The Optimal Dose of Sevoflurane Via Anaconda® in Post-operative Patient Underwent Head & Neck Surgery
Sedation in the ICUs is very common. There is no ideal sedative yet, so research has been conducted to replace propofol and midazolam, which are the most commonly used sedatives in ICUs, by inhalation anesthetics.
- Trial name
- NCT03559920
- Testing
- Sedate using sevoflurane via anesthetic conserving device(ACD, Anaconda®) after surgery, Sedate using propofol.
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Yonsei University
Cancer of Pancreas
Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery
The purpose of this randomized controlled trial is to investigate the effects of epidural anesthesia and analgesia on the overall survival，disease-free survival and recovery in patients undergoing pancreatic cancer surgery.
- Trial name
- NCT03245346
- Testing
- GEA, PCEA, GA
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Fudan University
Obstructive Sleep Apnea
Fentanyl Test and A Short OSAS Screening Scale for Severe Obstructive Sleep Apnea
The aim of this study was to estimate and compare the value of the preoperative fentanyl test and the short OSAS screening scale to diagnose severe obstructive sleep apnea；and to observe the required amount of hydromorphone and…
- Trial name
- NCT03705780
- Testing
- the short OSAS scale, fentanyl test
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Anesthesia
Preconditioning Volatile Anesthesia in Liver Surgery
The purpose of this study is to compare the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.
- Trial name
- NCT01021228
- Where
- Switzerland
- Volunteers
- 257 people
- Sponsor
- University of Zurich
Acute Appendicitis, Postoperative Pain
Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy
Intravenous lidocaine - a potent local anesthetic with analgesic and anti-inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Acute Appendicitis, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT03886896
- Testing
- Lidocaine
- Where
- Poland
- Volunteers
- 74 people
- Sponsor
- Medical University of Warsaw
Valvular Heart Disease
Sevoflurane's Effect on Mitral Valve Annular Velocity in Cardiac Surgery
The purpose of this study is to determine sevoflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery.
- Trial name
- NCT01511991
- Testing
- Sevoflurane dosage titration
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Konkuk University Medical Center
Immunotoxicity, Anesthesia
Anesthetic Depth Effects Upon Immune Competent Cells
Anesthesia depth affects the proliferation of lymphocytes to NK-cells and memory T-cells effect and the phagocytosis activity of macrophages in healthy patients.
- Conditions
- Immunotoxicity, Anesthesia, Inert Gas Narcosis
- Trial name
- BIS-MA (NCT02794896)
- Testing
- High dose propofol, fentanyl and sevoflurane, Low dose propofol, fentanyl and sevoflurane
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Heidelberg University
Paediatrics, General Anaesthesia
Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane…
- Trial name
- NCT04771962
- Testing
- DESFLURANE AND SEVOFLURANE
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Postoperative Delirium (POD), Diabetes
Impact of Sevoflurane Versus Propofol on Postoperative Delirium in Elderly Diabetic Patients Undergoing Non-Cardiac Surgery: a Multicenter, Randomized Controlled Trial
The present study is a multicenter， randomized controlled clinical trial, which plans to enroll 450 diabetic patients aged more than 60 years.
- Trial name
- NCT06788743
- Testing
- TIVA ( anesthesia with propofol and remifentanil), VA（anesthesia with sevoflurane and remifentanil）
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Xijing Hospital
Aortocoronary Bypass, Cardiac Surgery
Volatile Anesthetics to Reduce Mortality in Cardiac Surgery
There is initial evidence that the choice of anesthesia can influence survival in the specific setting of coronary artery bypass grafting surgery (CABG).
- Conditions
- Aortocoronary Bypass, Cardiac Surgery, Coronary Artery Bypass Grafting
- Trial name
- MYRIAD (NCT02105610)
- Testing
- desflurane, isoflurane, sevoflurane, total intravenous anesthetics
- Where
- 36 sites in Bahrain, Brazil and 11 more
- Volunteers
- 5,400 people
- Sponsor
- Università Vita-Salute San Raffaele
Vascular Surgery
Evaluate the Muscle Protection Effect of Sevoflurane Sedation in Vascular Surgery
Halogenated anaesthetic agents (HAA) may induce protective processes by pre-conditioning the myocardium. All of the literature shows that HAA induce pre-conditioning, thanks to a class effect, and Sevoflurane is the most widely…
- Trial name
- PHAR (NCT03215446)
- Testing
- maintenance of anaesthesia with propofol, maintenance of anaesthesia with sevoflurane
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anesthesia, Tolerance
Tolerance to Sevoflurane in Children Undergoing Repeated Drug Exposure
Deep sedation or general anesthesia is frequently required for infant that need radiotherapy to treat malignancies. As radiation therapy usually consist of several sessions, these patients are exposure to several consecutive…
- Trial name
- NCT04188782
- Testing
- Sevoflurane
- Where
- 2 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Sevoflurane
The Relationship of Sevoflurane Consumption With Metabolic Age
The aim of this clinical study is to determine the consumption of sevoflurane, which is one of the inhalation anesthetics, with metabolic age and basal metabolic rate.
- Trial name
- NCT06018597
- Testing
- Sevoflurane Baxter, 100%, Inhalation Vapour, Liquid 250 mL
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- Inonu University
Myocardial Reperfusion Injury
Sevoflurane and Isoflurane - During Cardiopulmonary Bypass With the MECC System (Minimized Extracorporeal Circuit)
The use of volatile anesthetics in cardiac anesthesia is very common, because of their cardioprotective effects and their ability to ensure a sufficient depth of anesthesia.
- Trial name
- NCT01601795
- Testing
- Sevoflurane, Isoflurane
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Pediatric Patients, Cardiology
A Comparison Of The Effect Of Target-Controlled Infusion Anesthesia And Inhalation Anesthesia
A total of 70 patients who underwent angiographic examination, ASD closure, VSD closure, PDA closure and aortic balloon dilatation were included in this study.
- Trial name
- NCT06265610
- Testing
- TIVA/TCI
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Mandibular Prognathism, Mandibular Retrognathism
The Effect of Deliberate Hypotension on QTc, Tp-e Intervals and Heart Rate Variability
Deliberate hypotension is defined as lowering the systolic blood pressure to 80-90mmHg, or the mean blood pressure to 50-65mmHg.
- Trial name
- NCT01634594
- Testing
- Group R, Group N, Group D
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Sleep Quality, General Anesthesia
The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep
Adequate sleep is necessary for physical and mental health of human being. Although surgery and anesthesia techniques have improved in resent years, postoperative sleep disturbance remains a challenging problem in surgical…
- Conditions
- Postoperative Sleep Quality, General Anesthesia, Propofol, Sevoflurane
- Trial name
- NCT04123249
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Yanchao Yang
Anesthesia, Pain
Sevoflurane's Effect on Neurocognition Study
The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose sevoflurane.
- Conditions
- Anesthesia, Pain, Amnesia
- Trial name
- SENS (NCT06044740)
- Testing
- Sevoflurane, Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Oxidative Stress, Sevoflurane Anaesthesia
Effect of Paracetamol Administration Timing on Oxidative Stress in Children Undergoing Sevoflurane Anesthesia
This study investigated the effects of paracetamol administration on oxidative stress in children undergoing inguinal hernia surgery under sevoflurane-based general anesthesia.
- Trial name
- NCT07903259
- Testing
- paracetamol (acetaminophen) solution commercial
- Where
- Serbia
- Volunteers
- 49 people
- Sponsor
- University of Belgrade
Spinal Disease
General Anesthesia and Regional Cerebral Oxygenation inSpine Surgery Prone Position
Elderly patients are reportedly at higher risk of postoperative cognitive dysfunction (POCD).The authors hypothesized that the incidence of POCD would be affected by several factors including, the age of the patient, the degree…
- Trial name
- NCT05148637
- Testing
- Maintenance of general anesthesia by Sevoflurane, Maintenance of general anesthesia by Desflurane, Anesthesia was maintained by inhalational anesthesia (total intravenous anesthesia by lidocaine, propfol and fentanyl infusions)
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University