Clinical trials: Sevoflurane, completed
Frailty
Intraoperative EEG Marker of Preoperative Frailty in Elderly Patients
Frailty is a state of vulnerability, characterized by a loss of mechanisms that maintain homeostasis, determining a lower capacity for recovery in the event of a stressful incident.
- Trial name
- NCT04783662
- Testing
- Intraoperative frontal electroencephalogram
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Sedation Complication
Comparison Between Sevoflurane and Propofol for Maintenance of Sedation During ERCP
After approval of ethical committee of Sindh Institute of Urology \& Transplantation (SIUT), 86 patients were enrolled for the elective endoscopic retrograde cholangiopancreatography (ERCP).
- Trial name
- NCT05996588
- Testing
- Propofol 1 % Injectable Suspension, Sevoflurane
- Where
- Pakistan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Pain, Monitoring, Intraoperative
Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial
After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively in infants, children and adolescents.
- Trial name
- Pain@OR-kids (NCT03449732)
- Testing
- PDR measurement
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Pregnancy Related
Different Anesthesia Methods on Development of Postnatal Depression After Cesarean Delivery
Childbirth is one of the most painful experiences for a woman. Labor and period of pregnancy is associated with an increased risk of psychiatric disorders for a woman.
- Trial name
- NCT04565730
- Testing
- Grup I= General anesthesia group, Grup II= Spinal anesthesia group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Medipol University
Sedation for Children Undergoing MRI
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: will receive oral Melatonin and nasal Sevoflurane.
- Trial name
- NCT06606899
- Testing
- Melatonin 3 MG, Chloral Hydrate, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia With Use of LMA (Laryngeal Mask Airway)
Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia
The aim of this study is first to assess if desflurane is superior in order to achieve a faster emergence from anesthesia.
- Trial name
- NCT02322502
- Testing
- Desflurane, Sevoflurane, propofol
- Where
- 4 sites in Germany
- Volunteers
- 352 people
- Sponsor
- RWTH Aachen University
Balanced Anesthesia
Surgical Pleth Index (SPI) Guided Analgesia During Sevoflurane Anesthesia
The aim of the present study was to compare SPI guided analgesia with standard clinical practise during general anesthesia using a balanced setting of sevoflurane and sufentanil anesthesia.
- Trial name
- NCT01525537
- Testing
- administration of sufentanil, sufentanil
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University Hospital Schleswig-Holstein
Pain, Postoperative, Phimosis
An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT04646967
- Testing
- Bupivacain, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Hemodynamic Stability
Hemodynamic Stability During Carotid Endarterectomy.Comparison of LENOXe™ (Xenon 100% v/v) Versus Sevoflurane
The purpose of this study is to compare the hemodynamics effects of two usual hypnotic agents (LENOXe ™ (xenon 100 % v/v) and sevoflurane) during a general anesthesia for carotid endarterectomy in elderly patients.
- Trial name
- NCT00937807
- Testing
- xenon, sévoflurane
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Air Liquide Santé International
Analgesia, Anesthesia
Analgesic Depth Evaluation During General Anesthesia With Dexmedetomidine-remifentanil Infusion. A Pilot Study
The aim of this study is to verify the feasibility of an evaluation of the depth of analgesia during an opioid sparing anesthesia (OSA) carried out with continuous infusion of dexmedetomidine in addition to general multimodal…
- Trial name
- NCT05785273
- Testing
- Pupillometer
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Università degli Studi di Brescia
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Hypotension During Surgery
Controlled Hypotension in Rhinoplasty and Septoplasty: Incidence of Cognitive Dysfunction and Delirium
Controlled hypotension application is a commonly preferred anesthesia practice during surgical procedures, particularly in regions with rich tissue perfusion, aiming to reduce bleeding, enhance surgical field visibility, and…
- Trial name
- NCT06238973
- Testing
- Group Low, Group Middle
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University
Pediatric Urinary Disorders
Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction
Dose titration of propofol for tracheal intubation in children with sevoflurane inhalation induction.
- Trial name
- NCT01084031
- Testing
- propofol
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Anesthesia
Anesthesia and Lymphocytes Apoptosis
Most researches revealed that volatile anesthetic sevoflurane has a more marked cardioprotective effect against ischemia compared with intravenous agent propofol.However, propofol has been suggested to be more benefit for…
- Trial name
- OPCAB (NCT01461551)
- Testing
- Sevoflurane, Propofol, combine of sevoflurane and propofol
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruijin Hospital
Uterus Myoma, Uterine Cancer
Effect of Anesthetic Agents on Optic Nerve Sheath Diameter
The present study is to evaluate the effect of anesthetic agents ( propofol , sevoflurane) on intracranial pressure of female patients undergoing laparoscopic-robotic surgery.
- Trial name
- NCT03701529
- Testing
- Sevoflurane, Propofol
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Pain, Postoperative, Phimosis
Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT02973958
- Testing
- Bupivacaine, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Auditory Brainstem Response
Comparative Effects of Two Anesthetic Techniques on Auditory Brain Response in Children
This will be a prospective, blinded, cross-over study to compare the effects of two anesthetic techniques on the interpretability of auditory brainstem response testing in children.
- Trial name
- NCT02830815
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events
Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia
This randomized controlled study is to evaluate the effectiveness of inhaling penehyclidine hydrochloride in reducing perioperative respiratory adverse events in children at risk undergoing minor elective surgery.
- Conditions
- Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events, Anticholinergics, Inhalation Therapy; Complications
- Trial name
- PEPSI (NCT06624696)
- Testing
- Penehyclidine hydrochloride, Normal Saline
- Where
- 2 sites in China
- Volunteers
- 204 people
- Sponsor
- Sun Yat-sen University
AKI - Acute Kidney Injury
Sevoflurane and Dexmedetomidine's Contrasting Renal Impacts After Non-Cardiac Surgery
Postoperative acute kidney injury (PO-AKI) is a significant complication, especially after complex surgeries. The choice of anesthetic may influence PO-AKI risk.
- Trial name
- NCT06835010
- Testing
- Dexmedetomidine, Sevoflurane inhalant product
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Postoperative Complications, Hip Fracture
A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia
This pilot project will address the gaps in knowledge regarding the effect of anesthetic technique on the risk of delirium through an adequately-powered trial employing standardized regimens for treatment and outcome assessment…
- Conditions
- Postoperative Complications, Hip Fracture, Delirium
- Trial name
- NCT02190903
- Testing
- General endotracheal anesthesia, Regional (spinal) Anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania