Clinical trials: Standard treatment
Intra Cerebral Hemorrhage
Maximal Medical Treatment of Intracerebral Haemorrhage Pilot Trial - MAX-ICH Pilot Trial
The MAX-ICH pilot trial is a phase-II study aimed at assessing the feasibility and safety of a comprehensive care bundle for patients with intracerebral hemorrhage (ICH).
- Trial name
- MAX-ICH (NCT06648369)
- Testing
- MAX-ICH care bundle, Standard of care
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
PreDiabetes, Diabetes Mellitus, Type 2
Acceptance and Commitment Therapy Principles for Diabetes Prevention
The investigators will evaluate whether a brief intervention (i.e. a workbook and video presenting educational information and activities materials for diabetes prevention) that incorporates principles drawn from focused…
- Conditions
- PreDiabetes, Diabetes Mellitus, Type 2, Diabetes, Diabetes type2
- Trial name
- NCT05260983
- Testing
- Diabetes Prevention Education and Acceptance and Commitment Therapy, Diabetes Prevention Education Only
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Oregon
Malignant Pleural Mesothelioma
Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma
The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure how people respond to standard treatment for malignant pleural mesothelioma (MPM).
- Trial name
- NCT06037941
- Testing
- E-Nose testing, Research blood
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Alcohol-Related Disorders, Alcoholism
Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol Addiction
This clinical study is being conducted to compare the effectiveness of two psychological treatments for alcohol addiction: Combined Behavioral Intervention (CBI) and Ericksonian Hypnotherapy (EH).
- Conditions
- Alcohol-Related Disorders, Alcoholism, Substance-related Disorders
- Trial name
- NCT06916754
- Testing
- Combined Behavioral Intervention, Ericksonian Hypnotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Beykoz University
COVID19
Assessment of the Effect of Convalescent Plasma Therapy in Patients With Life-threatening COVID19 Infection
This clinical trial proposal is based on the FDA protocol for emergency use of convalescent plasma for treatment of COVID-19 cases, and on the WHO guidelines for use of convalescent plasma in other infectious diseases.
- Trial name
- CP IN COVID19 (NCT04438694)
- Testing
- Convalescent Plasma, Standard of Care
- Where
- Egypt
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility, Female
Progesterone-modified Natural Cycle for FET
Hormone replacement therapy (HRT) cycles, despite the ease of synchronizing embryo thawing and embryo transfer timing, increase the risk of pregnancies and obstetric complications compared to natural cycles (NC).
- Trial name
- COMPROSET (NCT06644794)
- Testing
- Progesterone-modified natural cycle preparation for frozen embryo transfer, Hormone replacement therapy cycle preparation for frozen embryo transfer
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Shandong University of Traditional Chinese Medicine
Stage II Breast Cancer, Stage IIA Breast Cancer
Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer
This randomized pilot phase I/II trial studies how well aerobic and strength training exercise works in improving fitness and arm health during and after radiation therapy consisting of regional nodal radiation in patients with…
- Conditions
- Stage II Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
- Trial name
- NCT03102866
- Testing
- Best Practice, Exercise Intervention, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic
This study investigates patients' perceptions of their doctor's or nurse's empathy during an in-person interaction with the doctor or nurse wearing personal protective equipment (PPE) compared to during a video interaction with…
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05102656
- Testing
- Best Practice, Discussion, Questionnaire Administration
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- M.D. Anderson Cancer Center
High Grade Sarcoma, Sarcoma
Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial
This phase II trial compares standard of care surgical resection to fluorescence-guided surgical resection using indocyanine green and fluorescence imaging for reducing unexpected positive margin rates in patients with sarcoma.
- Trial name
- NCT07650656
- Testing
- Electronic Health Record Review, Fluorescence Imaging, Fluorescence-Guided Surgery
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- City of Hope Medical Center
Breast Cancer
Evaluation and Modeling of the G-CSF Effect on the Evolution of Neutrophils During Chemotherapy Based on Eribulin
The anti-cancer cytotoxic chemotherapy is often the cause of neutropenia of grade IV or febrile neutropenia. Those neutropenia, in addition to being a comorbidity factor, result in dose reductions and/or temporary or permanent…
- Trial name
- EMEG-E-01 (NCT02841722)
- Testing
- ERIBULIN + G-CSF (Granulocyte-Colony Stimulating Factor)
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Centre Georges Francois Leclerc
Acute Ischemic Stroke
Feasibility Study of RapidPulseTM Aspiration System as Frontline Approach for Patients With Acute Ischemic Stroke
A feasibility study to evaluate the initial safety and performance of the RapidPulseTM Aspiration System in the treatment of patients with Acute Ischemic Stroke (AIS) due to Large Vessel Occlusion (LVO) in the intracranial ICA…
- Trial name
- PULSE-F (NCT05577351)
- Testing
- RapidPulseTM Aspiration System
- Where
- 2 sites in Georgia
- Volunteers
- 5 people
- Sponsor
- RapidPulse, Inc
Advanced Life Support Operational Skills and Theoretical Knowledge Learning and Memorization
Combined Interval Training and Scenario Simulation for ALS Training of Medical Students
This study aims to investigate medical students' mastery of advanced life support skills when using scenario-based simulation combined with intermittent training, compared to traditional teaching methods.
- Trial name
- NCT07239531
- Testing
- Traditional Training Group, Traditional Training plus Interval Training Group, Scenario Simulation Group
- Where
- China
- Volunteers
- 48 people
- Sponsor
- General Hospital of Ningxia Medical University
Acute Watery Diarrhea
Safety and Efficacy of Racecadotril in Children With Acute Watery Diarrhea
Acute watery diarrhea is a common cause of illness and hospitalization in children under five years of age, particularly in developing countries.
- Trial name
- NCT07392931
- Testing
- Racecadotril
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Punjab Rangers Teaching Hospital Lahore
Carcinoma, Non-small Cell Lung Cancer
Combination Therapy of Sintilimab and Anlotinib as a First-line Treatment in Advanced NSCLC (SUNRISE)
This is an open label, multi-center, randomized control phase II trial, to compare the efficacy and safety of sintilimab combined with anlotinib versus standard platinum-based chemotherapy as a first-line treatment in advanced…
- Trial name
- NCT04124731
- Testing
- sintilimab plus anlotinib, Chemotherapy
- Volunteers
- 98 people
- Sponsor
- Shanghai Chest Hospital
Cancer, Chemotherapeutic Agent Toxicity
Telemonitoring Platforms and Chemotherapy-Associated Toxicity
The primary objective of this trial is to evaluate the impact of a telemonitoring platform on patient satisfaction with care amongst adult cancer patients receiving chemotherapy.
- Trial name
- DETECT (NCT06077123)
- Testing
- Contigo Application
- Where
- 2 sites in Chile
- Volunteers
- 80 people
- Sponsor
- Universidad Nacional Andres Bello
HIV (Human Immunodeficiency Virus)
Boosting Olfactory and Sensory Training Study (BOOST)
The goal of this study is to examine two types of olfactory interventions (conventional olfactory training vs scented marker training) in adults with HIV. The two research questions are: 1.
- Trial name
- BOOST (NCT07221123)
- Testing
- Conventional Smell Training Group, Scented Marker Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Cutaneous Lupus Erythematosus
Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
The primary objective of this study is to evaluate the safety and tolerability of edecesertib (formerly GS-5718) in participants with cutaneous lupus erythematosus (CLE) with or without systemic lupus erythematosus (SLE).
- Trial name
- LYNX (NCT04809623)
- Testing
- Edecesertib, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 3 people
- Sponsor
- Gilead Sciences
Pelvic Organ Prolapse
Guided IMagery and Patient Satisfaction (GIMPS) Following Urogynecological Surgery
We hypothesize that women who use GIM pre-operatively will feel more prepared for surgery, have less anxiety on the day of surgery and have higher satisfaction scores 6 weeks after surgery compared to women who undergo our…
- Trial name
- GIMPS (NCT02165280)
- Testing
- Guided IMagery (GIM)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loyola University
Breast Carcinoma, Endometrial Carcinoma
Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast Cancer
The purpose of this trial is to determine that sort term calorie restriction will affect tumor biology in biopsy proven breast, endometrial or prostate cancers, which will positively impact biomarkers including miR-21, an…
- Conditions
- Breast Carcinoma, Endometrial Carcinoma, Prostate Carcinosarcoma
- Trial name
- NCT02983279
- Testing
- Dietary Intervention, Counseling, Therapeutic
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Lung Cancer
Radiation Therapy in Patients With Limited-Stage Small Cell Lung Cancer in Complete Remission
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells and prevent the spread of cancer to the brain. It is not yet known if standard-dose radiation therapy is more effective than high-dose radiation therapy in…
- Trial name
- NCT00005062
- Testing
- radiation therapy
- Where
- 93 sites in United States, Australia and 26 more
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
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