Clinical trials: Standard treatment
Cancer
eSMART Trial to Evaluate ASyMS
Chemotherapy may cause distressing symptoms which can impact on patients' quality of life. Chemotherapy is frequently given on an outpatient basis therefore patients are often required to manage the symptoms they experience at…
- Trial name
- NCT02356081
- Testing
- ASyMS intervention Group
- Where
- 11 sites in Austria, Greece and 3 more
- Volunteers
- 829 people
- Sponsor
- Louise McKean
Neoplasms
Feasibility of an Advance Care Planning Intervention
Advanced Cancer patients hospitalized in a Cancer center inpatient unit have a dismal prognosis. Palliative Care interventions have shown multiple benefit for those patients, regarding quality of life, symptom management, illness…
- Trial name
- PREVOIR (NCT06149312)
- Testing
- Advance Care Planning Intervention
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institut de cancérologie Strasbourg Europe
Infection
Far-UVC and Infections in Long-term Care Facilities
Background Elderly residents in long-term care (LTC) facilities are highly susceptible to infections, often leading to hospitalizations and placing significant strain on the healthcare sector.
- Trial name
- NCT07511881
- Testing
- Far-uvc (222 nm), Standard Care (Treatment as Usual)
- Where
- Denmark
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Vejle Hospital
Lung Cancer
ENB Guided RFA for Early-stage Peripheral Lung Cancer
The objective of the study was to evaluate the efficacy and safety of electromagnetic navigation bronchoscopy (ENB) guided radiofrequency ablation (RFA) for the treatment of early-stage peripheral lung cancer.
- Trial name
- NCT03009630
- Testing
- RFA, ENB
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Chest Hospital
Streptococcal Pharyngitis, Group A Streptococcal Infection
A Multicenter Evaluation of SalivIQ™ Strep A for Detecting Group A Streptococcus From Saliva and Throat Swabs in Patients With Acute Pharyngitis
The goal of this observational study is to learn how well the SalivIQ™ Strep A test detects Group A Streptococcus, the bacteria that cause strep throat.
- Trial name
- NCT07891728
- Testing
- qPCR
- Where
- 3 sites in United States
- Volunteers
- 668 people
- Sponsor
- SalivIQ Diagnostics, Inc.
Cervical Cancer, Cervical Intraepithelial Neoplasias
Diagnostic Imaging Aid for Management of Cervical Lesions
A handheld digital colposcope which utilizes flurorescent light is being tested for the rapid detection and management of cervical lesions.
- Conditions
- Cervical Cancer, Cervical Intraepithelial Neoplasias, Digital Colposcopy, Precancerous Cervical Lesions
- Trial name
- FFC (NCT02406365)
- Testing
- Diagnostic imaging aid for one-visit management of cervical lesions
- Where
- United States
- Volunteers
- 618 people
- Sponsor
- Brookdale University Hospital Medical Center
Compression Neuropathy
Intraoperative Peripheral Nerve Stimulation
The purpose of this research study is to find out if using direct electrical stimulation during surgery is safe and helpful for people with nerve problems caused by compressed nerves.
- Trial name
- NCT07592065
- Testing
- Nerve Root Electrical Stimulation, Peripheral Nerve Electrical Stimulation, Standard Treatment - Nerve Root
- Sponsor
- Wake Forest University Health Sciences
Infants Admitted to Neonatal Units, NICU
Effects of Early Physiotherapy Program on the Infants in NICU
High-risk of Infants are defined as one with a history of negative environmental and biological factors that could lead to neuromotor developmental problems.
- Conditions
- Infants Admitted to Neonatal Units, NICU, NICU Infants, Family Centered Care
- Trial name
- NCT07201792
- Testing
- Early Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Non-Hodgkin Lymphoma
Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma
This is a randomized, open label, multicenter phase III trial comparing the efficacy, safety, and tolerability of tisagenlecleucel to Standard Of Care in adult patients with aggressive B-cell Non-Hodgkin Lymphoma after failure of…
- Trial name
- BELINDA (NCT03570892)
- Testing
- Tisagenlecleucel after optional bridging and lymphodepleting chemotherapy, Platinum-based immunochemotherapy followed in responding patients with high dose chemotherapy and autologous hematopoietic stem cell transplant (HSCT)
- Where
- 67 sites in United States, Australia and 16 more
- Volunteers
- 330 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Study of Efficacy and Safety of QAW039 When Added to Standard-of-care Asthma Therapy in Patients With Uncontrolled Asthma
A randomized, multicenter, double-blind, placebo- controlled parallel-group study to determine the efficacy and safety of QAW039, compared with placebo, when added to standard-of-care (SoC) asthma therapy in adult and adolescent…
- Trial name
- NCT03226392
- Testing
- QAW039
- Where
- 142 sites in United States, Brazil and 16 more
- Volunteers
- 704 people
- Sponsor
- Novartis Pharmaceuticals
Fibromyalgia
Efficacy of NAT-FM Treatment for Fibromyalgia
The main objective of this study is to analyse the efficacy of the NAT-FM multicomponent treatment program as coadjuvant of treatment-as-usual (TAU) compared to TAU alone.
- Trial name
- NAT-FM (NCT04190771)
- Testing
- TAU + multicomponent treatment NAT-FM, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 169 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Atrial Fibrillation (AF)
Evaluation of Probiotics' Effect on Atrial Fibrillation Recurrence in Patients Undergoing Cardioversion
The aim of this clinical study is to evaluate the efficacy and tolerability of probiotics on atrial fibrillation recurrence.
- Trial name
- NCT07568964
- Testing
- Anticoagulant Therapy, Probiotics capsules
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Acromegaly Due to Pituitary Adenoma
Multicenter Evaluation of the Effect of Upfront Radiosurgery on Residual Growth Hormone-secreting Pituitary Adenoma
In this study, the investigators hypothesize that upfront gamma knife radiosurgery with drug therapy is superior in the treatment of growth hormone-secreting pituitary tumors after primary surgical treatment compared with the…
- Trial name
- MERGE (NCT03439709)
- Testing
- Gamma knife radiosurgery, Lanreotide 60Mg Solution for Injection
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Aging, Fall Injury Prevention
Older Adult Traditional Balance Training vs Traditional Balance Training Plus Neck Strengthening
This study promotes greater understanding of factors impacting balance and how neck strength alters specific aspects of impaired balance.
- Conditions
- Aging, Fall Injury Prevention, At Fall Risk
- Trial name
- NCT07503899
- Testing
- Neck Strengthening Exercises
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Ohio University
Knee Osteoarthritis, Chronic Post Operative Pain
Opioid Reduction in Orthopaedic Surgery (OREOS) - Knees
Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery.
- Trial name
- OREOS (NCT04968132)
- Testing
- Multicomponent opioid reduction and pain management pathway, Standard care
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Kim Madden
Rotator Cuff Syndrome, Rotator Cuff Injuries
Mulligan and Proprioceptive Neuromuscular Facilitation Techniques in Individuals With Rotator Cuff Lesions
This study aims to compare the effects of Mulligan mobilization with movement (MWM) and Proprioceptive Neuromuscular Facilitation (PNF) techniques on pain, functionality, proprioception, and quality of life in individuals…
- Trial name
- NCT07294729
- Testing
- Control Group (Conventional Physiotherapy), Mulligan Mobilization, Proprioceptive Neuromuscular Facilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Medipol University
Traumatic Brain Injuries, TBI (Traumatic Brain Injury)
Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)
The primary goal of this study is to evaluate the effectiveness of an integrated therapeutic model - combining VR and standard psychotherapy in improving executive function and hyperarousal adults impacted with mTBI.
- Conditions
- Traumatic Brain Injuries, TBI (Traumatic Brain Injury), MTBI - Mild Traumatic Brain Injury, mTBI
- Trial name
- ReVIVE (NCT07890337)
- Testing
- Virtual Reality, Standard Psychotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Postoperative Pain
Effects of Connective Tissue Massage on Pain After Thoracotomy
Pain can be quite severe after thoracic surgery and effective pain control is highly effective in preventing secretion accumulation, atelectasis, infection and hypoxemia.
- Trial name
- NCT05617937
- Testing
- Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Akdeniz University
Balanced Anesthesia
Surgical Pleth Index (SPI) Guided Analgesia During Sevoflurane Anesthesia
The aim of the present study was to compare SPI guided analgesia with standard clinical practise during general anesthesia using a balanced setting of sevoflurane and sufentanil anesthesia.
- Trial name
- NCT01525537
- Testing
- administration of sufentanil, sufentanil
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University Hospital Schleswig-Holstein
Opioid Withdrawal, Pain
BRIDGE Device for Treatment of Opioid Withdrawal
The purpose of this study is to prospectively evaluate the effectiveness of the NSS-2 BRIDGE device in reducing the signs and symptoms of acute opioid withdrawal when compared to placebo.
- Conditions
- Opioid Withdrawal, Pain, Craving
- Trial name
- NCT04162145
- Testing
- Active BRIDGE device placement, Inactive BRIDGE device placement
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BrightView LLC
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