Clinical trials: Stereotactic Body Radiation Therapy
Ventricular Tachycardia, Myocardial Infarction
Cohort Study - SBRT for VT Radioablation
Ventricular tachycardia (VT) contributes to over 350,000 sudden deaths each year in the US. Malignant VTs involve an electrical "short circuit" in the heart, formed by narrow channels of surviving tissue inside myocardial scar.
- Conditions
- Ventricular Tachycardia, Myocardial Infarction, Heart Disease Structural Disorder
- Trial name
- NCT04162171
- Testing
- Stereotactic Body Radiotherapy (SBRT) ablation of VT
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- John Sapp
Non-metastasized Unresectable Pancreatic Carcinoma
Stereotactic Body Radiation Therapy for Inoperable Non-metastasized Pancreatic Adenocarcinoma
This is a multicenter randomized phase II trial that aims to include 160 patients with a non-metastatic (localized), inoperable pancreatic tumor. The study will take place at multiple centers across Europe.
- Trial name
- TORPEDO (NCT06691425)
- Testing
- Stereotactic Body Radiation Therapy (SBRT), Chemotherapy
- Where
- 9 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Cancer Research Antwerp
Prostate Adenocarcinoma
Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer
This phase 2 trial studies radium Ra 223 dichloride, hormone therapy and stereotactic body radiation in treating patients with prostate cancer that has spread to other places in the body.
- Trial name
- NCT03361735
- Testing
- Leuprolide Acetate, Goserelin Acetate, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- City of Hope Medical Center
Glioblastoma
Post-operative Adjuvant Therapy w/wo GammaTile + Systemic Therapy
To compare surgical tumor removal and GammaTile therapy followed by adjuvant systemic therapy (bevacizumab or lomustine) to surgical tumor removal followed by adjuvant systemic therapy (bevacizumab or lomustine) without GammaTile…
- Trial name
- PATHWAyS (NCT05900908)
- Testing
- Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Stereotactic Radiation Therapy
- Sponsor
- GT Medical Technologies, Inc.
The Efficacy and Safety of SBRT in MPLC
The Effectiveness and Safety of SBRT in the Treatment of Patients With MPLC After Surgery (SMILE)
To prospectively evaluate the effectiveness and safety of SBRT in the treatment of residual malignant pulmonary nodules after lung cancer, and is committed to providing new treatment options for patients with multiple primary…
- Trial name
- SMILE (NCT05113017)
- Testing
- NO Intervention
- Where
- 5 sites in China
- Volunteers
- 40 people
- Sponsor
- Fang Wu
Hepatocellular Carcinoma
Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Patients With Hepatocellular Carcinoma
The objective of this study is to evaluate the efficacy and safety of Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Patients in hepatocellular carcinoma.
- Trial name
- NCT03857815
- Testing
- anti-PD-1 antibody
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
Non Small Cell Lung Carcinoma
Protocol for Primary Fractionated Stereotactic Body Radiation Therapy for Stage T1 - T3N0 Non Small Cell Lung Carcinoma.
The study population will exist of patients with a histological diagnosis of NSCLC, stage T1, T2 or T3NO who are not fit for or who refuse surgery.
- Trial name
- NCT00727350
- Testing
- Fractionated stereotactic body radiation therapy
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Universitair Ziekenhuis Brussel
Stage I Prostate Adenocarcinoma, Stage II Prostate Adenocarcinoma
Stereotactic Body Radiation Therapy With Boost Using Urethral-Sparing Intensity-Modulated Radiation Therapy Planning in Treating Patients With Prostate Cancer
This phase I/II trial studies the side effects and best dose of stereotactic body radiation therapy while using intensity-modulated radiation therapy (IMRT) planning to help avoid radiation to normal tissue in patients with…
- Trial name
- NCT02470897
- Testing
- Radiation Therapy Treatment Planning and Simulation, SBRT
- Where
- 3 sites in United States
- Volunteers
- 115 people
- Sponsor
- University of Wisconsin, Madison
Lung Cancer
Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
RATIONALE: Stereotactic body radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Trial name
- NCT00471835
- Testing
- computed tomography, positron emission tomography, stereotactic body radiation therapy
- Sponsor
- Wake Forest University Health Sciences
Radiotherapy, Microwave Ablation
Clinical Efficacy of Stereotactic Radiotherapy and Microwave Ablation for Liver Metastases From Colorectal Cancer.
Data of 100 colorectal cancer patients with liver metastases who received stereotactic radiotherapy of Cyberknife or microwave ablation in the multicenter of the research group from June 2019 to May 2021 were collected, as well…
- Conditions
- Radiotherapy, Microwave Ablation, Liver Metastases, Colorectal Cancer
- Trial name
- Ckvsmalm (NCT03963726)
- Testing
- stereotactic radiotherapy, microwave alabation
- Where
- 6 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Brain Metastases, Radiotherapy
Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases
This is a prospective, multicenter, randomized, controlled clinical study of NSCLC patients with intracranial oligo-metastatic EGFR-sensitive mutations treated with EGFR-TKI Almonertinib , according to the implementation time of…
- Conditions
- Brain Metastases, Radiotherapy, EGFR Activating Mutation
- Trial name
- NCT05768490
- Testing
- brain radiotherapy, Almonertinib
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Sun Yat-sen University
Unspecified Adult Solid Tumor, Protocol Specific
Extracranial Stereotactic Radiosurgery in Treating Patients With Solid Tumors
RATIONALE: Extracranial stereotactic radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Trial name
- NCT00311597
- Testing
- Radiosurgery
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Wake Forest University Health Sciences
Pancreatic Cancer Non-resectable
Efficacy of Stereotactic Body Radiotherapy (SBRT) Combined With Maintenance Therapy Compared to Maintenance Therapy Alone in Advanced Pancreatic Cancer
This is a Phase II, multicenter, randomized controlled trial to assess the efficacy of Stereotactic Body Radiotherapy (SBRT) in combination with maintenance therapy in patients with advanced pancreatic cancer.
- Trial name
- NCT07600268
- Testing
- Stereotactic Body Radiotherapy (SBRT) with maintenance therapy, Maintenance therapy
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Shandong Cancer Hospital and Institute
Metastatic Castrate- Resistant Prostate Cancer
Idronoxil Suppository Combine With Radiotherapy for Metastatic Prostate Cancer
The aim of the study is to determine the toxicity of Idronoxil (NOX66) when used in combination with palliative radiotherapy for metastatic prostate cancer
- Trial name
- NCT03041285
- Testing
- idronoxil (NOX66) suppository, Stereotactic Body Radiation Therapy
- Where
- Australia
- Volunteers
- 1 people
- Sponsor
- Royal North Shore Hospital
Locally Advanced Skin Squamous Cell Carcinoma, Resectable Skin Squamous Cell Carcinoma
Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCC
This phase I trial tests the safety and side effects radiotherapy in combination with atezolizumab in treating patients with cutaneous squamous cell cancer that has spread to nearby tissue or lymph nodes (locally advanced) and…
- Conditions
- Locally Advanced Skin Squamous Cell Carcinoma, Resectable Skin Squamous Cell Carcinoma, Unresectable Skin Squamous Cell Carcinoma
- Trial name
- NCT05085496
- Testing
- Atezolizumab, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer
Stereotactic Body Radiotherapy (SBRT) Post Prostatectomy
This phase I study will assess the toxicity profile and efficacy of SBRT (Stereotactic body radiotherapy) in patients with localized prostate cancer who are considered candidates for post-prostatectomy radiation.
- Trial name
- PLUTO-MPC (NCT04848909)
- Testing
- stereotactic body radiotherapy (SBRT)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostate Cancer Metastatic
Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer
The purpose of this study is to compare the effects of ablative therapy (radiation or surgery) to all sites of disease combined with standard treatments on prostate cancer, compared to the standard or usual treatments used to…
- Trial name
- PLATON (NCT03784755)
- Testing
- Ablative Radiation Therapy, Standard of care
- Where
- 18 sites in Canada
- Volunteers
- 409 people
- Sponsor
- Canadian Cancer Trials Group
Resectable Hepatocellular Carcinoma, Macrovascular Invasion
Neoadjuvant SBRT Combined With Lenvatinib and Pucotenlimab for Resectable Hepatocellular Carcinoma
At the time of diagnosis, the majority of hepatocellular carcinoma (HCC) patients are at the intermediate to advanced stages, with a 50-70% incidence of macrovascular invasion (including portal vein, hepatic vein, inferior vena…
- Conditions
- Resectable Hepatocellular Carcinoma, Macrovascular Invasion, CNLC IIIA Stage
- Trial name
- NCT06524466
- Testing
- Neoadjuvant SBRT combined with Lenvatinib and Pucotenlimab
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Sun Yat-sen University
Clear-cell Metastatic Renal Cell Carcinoma
Pembrolizumab Plus Radiotherapy for Advanced Renal Cancer
This study is designed as a phase-II proof of clinical trial to investigate if a treatment strategy where stereotactic body radiation therapy (SBRT) is given with pembrolizumab is sufficiently active to warrant further…
- Trial name
- NCT05567588
- Testing
- Drug: Pembrolizumab
- Where
- 2 sites in China
- Volunteers
- 66 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Carcinoma, Hepatocellular, Intrahepatic Cholangiocarcinoma
Stereotactic Body Radiotherapy for Hepatocellular Carcinoma, and Intrahepatic Cholangiocarcinoma
This study is being done to determine if targeted radiation therapy (stereotactic) can be given to treat liver cancer, for patient who are unable to undergo surgery, over a short period of time with a small amount of side effects.
- Trial name
- NCT01668134
- Testing
- Stereotactic radiation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
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