Clinical trials: Transcranial Direct Current Stimulation
Alzheimer Disease
Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheimer's Disease
There is currently little symptomatic therapy for Alzheimer's Disease (AD) and nothing effective for individuals with Frontotemporal dementia (FTD).
- Trial name
- NCT05509387
- Testing
- transcranial direct current stimulation and naming training
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Baycrest
Visual Field Defect, Stroke
Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual…
- Conditions
- Visual Field Defect, Stroke, Hemianopia, Quadrantanopia
- Trial name
- VIBRANT (NCT07105358)
- Testing
- transcranial random noise stimulation (tRNS), Perceptual learning-based training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgetown University
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD
The purpose of this study is to examine comparative effectiveness of two home-based telemedicine delivered interventions: transcranial Direct Current Stimulation (tDCS) combined with Massed Prolonged Exposure (Massed-PE) vs.
- Trial name
- NCT07116109
- Testing
- Transcranial Direct Current Stimulation (tDCS), Massed-Prolonged Exposure (PE)
- Where
- 2 sites in United States
- Volunteers
- 146 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stuttering, Fluency Disorders
Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering
This study aims to test whether the addition of transcranial direct current stimulation (TDCS) to speech fluency training results in improvements in speech fluency in adults with developmental stuttering.
- Conditions
- Stuttering, Fluency Disorders, Speech Disorders
- Trial name
- NCT02288598
- Testing
- Anodal TDCS, Fluency Training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Fibromyalgia
Direct Current Stimulation for Treatment of Fibromyalgia
The aim of this study is to assess the effectiveness of transcranial direct current stimulation (tDCS) in treating fibromyalgia.
- Trial name
- NCT02704611
- Testing
- Real tDCS
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Dina Hatem Elhammady
Major Depressive Disorder
Transcranial Direct Current Stimulation Therapy for Major Depression
Depression is a prevalent and debilitating disorder. The most common treatments are antidepressant medications and talking therapies. However, for many individuals, these are not their treatment of choice.
- Trial name
- NCT03632434
- Testing
- transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of East London
Glaucoma
Cross-modal Neuromodulation to Improve Balance and Cognition in Older Adults With Glaucoma: A Randomized Trial of Cerebellar Transcranial Electrical Stimulation
The goal of this clinical trial is to use different tES techniques to constantly stimulate the cerebellum in older glaucoma patients. The main questions aim to answer : 1.
- Trial name
- NCT07771699
- Testing
- transcranial electrial stimulation
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Oropharyngeal Dysphagia, Stroke
Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation
According WHO, oropharyngeal dysphagia (OD) is a prevalent post-stroke (PS) condition involving the digestive system (ICD-10: I69.391) and an independent risk factor for malnutrition and pulmonary infection; and leads to greater…
- Conditions
- Oropharyngeal Dysphagia, Stroke, Stroke, Complication, Swallowing Disorder
- Trial name
- ICI20/00117 (NCT05720871)
- Testing
- rTMS + capsaicin 150μM (natural TRPV1 agonist), tDCS + capsaicin 150μM (natural TRPV1 agonist)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital de Mataró
Stroke
Dextroamphetamine and tDCS to Improve the Fluency
The proposed study aims to evaluate safety and efficacy of combined dextroamphetamine (Dexedrine) and transcranial direct current stimulation (tDCS) with melodic intonation therapy (MIT) for treatment of aphasia after stroke.
- Trial name
- NCT02514044
- Testing
- Dexedrine, Active tDCS, Speech Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center, Houston
Epilepsy Intractable
Memory Retrieval and Encoding Investigated by Neural Stimulation
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain…
- Trial name
- MEMREINS (NCT04286776)
- Testing
- Direct electrical stimulation
- Where
- 11 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Pennsylvania
Vegetative State, Minimally Conscious State
Prefontal tDCS in Patients With Disorders of Consciousness: Neurophysiological and Behavioural Outcomes
Non-invasive brain stimulations techniques have recently shown promising results in patients with disorders. Notably, transcranial direct current stimulation (tDCS) applied over the left dorsolateral prefrontal cortex has proved…
- Conditions
- Vegetative State, Minimally Conscious State, Disorder of Consciousness
- Trial name
- NCT03823508
- Testing
- anodal tDCS
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University of Liege
Ataxia, Cerebellar, Cerebellar Ataxia
Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia
Neurodegenerative cerebellar ataxias represent a group of disabling disorders for which we currently lack effective therapies. Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been…
- Conditions
- Ataxia, Cerebellar, Cerebellar Ataxia, Spinocerebellar Ataxias, Ataxia, Spinocerebellar
- Trial name
- CStDCSAtaxia (NCT03120013)
- Testing
- Anodal cerebellar and cathodal spinal tDCS
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Depression, Pregnancy
Transcranial Direct Current Stimulation (tDCS) for Depression in Pregnancy: A Pilot Study
The purpose of this pilot study is to examine the feasibility of conducting a multi-site double-blind randomized controlled trial whose aim will be to evaluate the effectiveness of transcranial direct current stimulation (tDCS)…
- Trial name
- NCT02116127
- Testing
- Active tDCS
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Women's College Hospital
Anxiety
Effect of tDCS Along With Relaxation Technique on Anxiety Level in Students Preparing for Competitive Exams
Anxiety is one of the most significant obstacles to academic success. When stress is interpreted negatively or becomes overwhelming, it causes anxiety before and during examinations, which in turn impacts students' academic…
- Trial name
- NCT06176924
- Testing
- tDCS, Relaxation technique
- Where
- India
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Major Depression
Modulation of Cognitive Control by Transcranial Direct Current Stimulation
Insufficient cognitive control over emotional distracters is characteristic for major depressive disorder (MDD). Hypoactivation of the dorsolateral prefrontal cortex (dlPFC) is associated with this deficit.
- Trial name
- NCT01652391
- Testing
- Transcranial direct current stimulation (tDCS); DC-STIMULATOR (NeuroConn GmbH, Ilmenau, Germany)
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Osteoarthritis, Knee
Brain Stimulation and Meditation for Pain After Total Knee Arthroplasty
Feasibility, acceptability, and preliminary efficacy of combined transcranial direct current stimulation and mindfulness for pain after total knee arthroplasty
- Trial name
- NCT05673720
- Testing
- active tDCS paired with active MBM
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Florida State University
Obsessive Compulsive Disorder (OCD)
Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
Obsessive-compulsive disorder (OCD) is associated with substantial impairments in quality of life and is among the most disabling psychiatric disorders.
- Trial name
- NCT06834217
- Testing
- Active transcranial direct current stimulation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Convergence Insufficiency
Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency
The goal of this randomized controlled trial is to test the effectiveness of non-invasive brain stimulation in treating adults with symptomatic convergence insufficiency compared to vergence/accommodative therapy.
- Trial name
- NIBSCI (NCT05877560)
- Testing
- Anodal-Transcranial Direct Current Stimulation, Office-Based Vergence/Accommodative Therapy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Schizophrenic Patients
Effects of tDCS Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial direct current stimulation (tDCS) and retrieval practice have been demonstrated as external techniques…
- Trial name
- NCT06538259
- Testing
- Transcranial direct current stimulation (tDCS)-anodal group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Northeast Normal University
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