Clinical trials: Transcranial Direct Current Stimulation, completed
Depression, Anxiety and Fear
Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression
Over 50% of patients with major depressive disorder (MDD) do not respond to initial treatment and relapse is common. In particular, comorbid depression and anxiety disorders are associated with more treatment resistance.
- Trial name
- NCT04948944
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Healthy
Establish the Role of Premotor and Motor Cortices in tDCS-facilitated Speech Motor Learning
Groups of unimpaired participants will all receive speech motor training of nonwords, and six tDCS conditions will be compared: anodal tDCS over speech motor regions; cathodal tDCS over speech motor regions; anodal tDCS over left…
- Trial name
- NCT05804344
- Testing
- Anodal speech motor tDCS, Cathodal speech motor tDCS, Anodal IFG tDCS
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- New York University
Spinal Cord Injuries, Tetraplegia
Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function
Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
- Trial name
- NCT04777149
- Testing
- transcranial Random Noise Stimulation (tRNS), transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Shepherd Center, Atlanta GA
Chronic Stroke
tDCS and CO-OP in Chronic Stroke
This project seeks to evaluate the acceptability feasibility, practicality feasibility, and preliminary effect of combining transcranial direct current stimulation (tDCS) and metacognitive strategy training (MCST) in individuals…
- Trial name
- NCT04617548
- Testing
- tDCS and CO-OP Group
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obsessive-Compulsive Disorder
Enhancement of Therapeutic Learning in OCD Using tDCS
Psychiatric disorders characterized by pathological fear and anxiety are common and often disabling. Despite their limitations, exposure therapies are among the most efficacious treatments for these disorders.
- Trial name
- NCT03572543
- Testing
- tDCS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Attention Deficit Hyperactivity Disorder
TDCS for the Treatment of Inattention Symptoms in Adult ADHD Patients
This study aims at evaluating the efficacy and safety of a home-based tDCS device when compared to a sham stimulation for improving attention in adult ADHD patients.
- Trial name
- TUNED (NCT04003740)
- Testing
- Home-based transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Cognitive Dysfunction
Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery
Postoperative cognitive dysfunction (POCD) is a contrary event observed between 20 to 83%, especially on elderly and patients submitted to cardiac surgery.
- Trial name
- tDCS (NCT02549560)
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- University of Sao Paulo
Stroke
Transcranial Direct Current Stimulation (tDCS) in Chronic Stroke Recovery
The hypothesis of this study is that different subgroups of stroke will respond differently to direct current stimulation.
- Trial name
- NCT01014897
- Testing
- tDCS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Texas Southwestern Medical Center
Vegetative State, Minimally Conscious State
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- tDCS in DOC (NCT01673126)
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University of Liege
Epilepsy
High Definition Cathodal Transcranial Direct Current Stimulation for Treatment of Refractory Partial Onset Epilepsy
High-Definition transcranial Direct Current Stimulation (HD tDCS) Genuine cathodal HD-tDCS will be delivered through High-Definition electrodes that will be arranged on the skull according to a 4x1-ring configuration with the…
- Trial name
- HD-TDCS (NCT02264652)
- Testing
- HD Transcranial Direct Stimulation
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Pain, Chronic
Effects of Transcranial Direct Current Stimulation on Pain Control in Chronic Painful Total Knee Arthroplasty
The TSEF-PTG study aims to evaluate the effects of transcranial Direct Current Stimulation (tDCS) and exercise versus sham tDCS (placebo) and exercise on pain control in chronic painful total knee arthroplasty (TKA) patients.
- Trial name
- TSEF-PTG (NCT04579952)
- Testing
- transcranial Direct Current Stimulation
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Istituto Ortopedico Rizzoli
Trigeminal Neuropathic Pain
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain
The main goal of this study to integrate techniques producing images of the brain (also called neuroimaging techniques) with non-invasive brain stimulation to investigate factors that may be associated with chronic pain in…
- Trial name
- NCT03003715
- Testing
- PET Scans, transcranial direct current stimulation (tDCS), MRI
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Social Anxiety Disorder
The Effects of HD-tDCS on Cognitive Bias Among Individuals With Social Anxiety Symptoms
To examine the offline effects of high-definition tDCS (HD-tDCS) on attention, interpretation and memory biases in youth with social anxiety.
- Trial name
- NCT07099521
- Testing
- Active High-definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 74 people
- Sponsor
- South China Normal University
Schizophrenia
Treatment of Refractory Auditory Verbal Hallucinations With tDCS in Schizophrenia
The purpose of this study is to exploratively evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in patients with schizophrenia who experience persistent auditory verbal hallucinations after…
- Trial name
- NCT02451371
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Transcranial Direct Current Stimulation, Healthy
Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1
Non-invasive neuromodulation, such as transcranial direct current stimulation ( tDCS) , is emerging as an important therapeutic tool with documented effects on brain circuitry, yet little is understood about h ow it changes…
- Trial name
- MINUTES (NCT03896425)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Neurofibromatosis 1
Non-invasive Stimulation in Neurofibromatosis Type 1
Intellectual impairments are a significant cause of morbidity in children with birth defects along with long term implication on academic and occupational functioning.
- Trial name
- tDCS is NF1 (NCT03310996)
- Testing
- Transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Manchester
Depression, Anxiety
Enhancing the Effectiveness of Cognitive Behavioral Therapy Using Non-invasive Brain Stimulation
The purpose of the proposed study is to examine if a repeated treatment of High Definition Transcranial Direct Current Stimulation (HD-tDCS) can increase the functional connectivity between the left ventrolateral prefrontal…
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT05555056
- Testing
- MxN-9 HD-tES Stimulator (Soterix Inc.)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Schizophrenia
RCT of tDCS Combined With Cognitive Training in Schizophrenia
Given the superior effects of CT augmented tDCS in healthy subjects, the aim of the current study was to examine whether the effect of CT on cognition can be enhanced with concurrent anodal tDCS in schizophrenia patients.
- Trial name
- NCT04870996
- Testing
- tDCS, Cognitive Training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- CHAN SAU MAN, SANDRA
Aging
Optimizing tDCS to Improve Dual Task Gait and Balance
The objective of this study is to determine the acute effects of single sessions of optimized tDCS, conventional tDCS, and sham stimulation on dual task standing and walking in older adults who are free of overt disease yet who…
- Trial name
- OptiStim (NCT04295798)
- Testing
- Conventional tDCS, Optimized tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Treatment Resistant Major Depressive Disorder
Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD
This is a multi-site, randomized, open-label, effectiveness trial comparing three treatment arms for Major Depressive Disorder (MDD) patients with TRD who are currently on ongoing, stable and adequate antidepressant therapy…
- Trial name
- ASCERTAINTRD (NCT02977299)
- Testing
- Aripiprazole, Repetitive transcranial magnetic stimulation (rTMS), Venlafaxine XR
- Where
- 13 sites in United States, Canada
- Volunteers
- 278 people
- Sponsor
- Massachusetts General Hospital