Clinical trials: Transcranial Direct Current Stimulation
Cerebral Palsy (CP), Chronic Pain
Concurrent tDCS for Chronic Pain in Adults With Cerebral Palsy
The purpose of this study is to find out whether combining transcranial direct current stimulation (tDCS) using the Starstim tES8 device with motor-based activities, such as action observation or motor imagery (chosen based on…
- Trial name
- Neuropoint (NCT07846436)
- Testing
- Trans Cranial Direct Current Stimulation
- Volunteers
- 20 people
- Sponsor
- Gillette Children's Specialty Healthcare
Healthy Adults
Investigating the Neural Correlates in Memory Retrieval After HD-tDCS
The overall objective of this study is to investigate the neural correlate in retrieval memory task. The aim of the study is to understand the undergoing changes in late positive ERP component during retrieval memory task when…
- Trial name
- NCT03319134
- Testing
- active anodal HD-tDCS, active cathodal HD-tDCS
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Dyspepsia
Effectiveness of tDCS for the Treatment of Functional Dyspepsia
Functional dyspepsia is a very common disorder of great challenge to clinical management. A therapeutic targets is up-regulation of visceral pain threshold.
- Trial name
- NCT02611414
- Testing
- anodal tDCS
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Ernesto Dornelles
Seizures, Seizure Disorder
Modulating Movement Intention Via Cortical Stimulation
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies.
- Conditions
- Seizures, Seizure Disorder, Psychogenic Movement Disorder
- Trial name
- NCT03233399
- Testing
- rTMS of left or right angular gyrus (AG) or frontal cortex (FC), Anodal tDCS of left or right AG or FC
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Fibromyalgia
High-definition Transcranial Electrical Stimulation for Fibromyalgia
Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct current or alternating current to change the excitability of the cerebral cortex.
- Trial name
- NCT04550598
- Testing
- HD-tCES
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Taipei Medical University
ALS, ALS (Amyotrophic Lateral Sclerosis)
At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease that causes gradual muscle weakness and loss of muscle mass. It affects all muscles that control movement, speech, swallowing, and breathing.
- Trial name
- tDCS-ALS (NCT07006571)
- Testing
- Real tDCS
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Trieste
Healthy
Effects of Different Intensities of Bilateral- and Cathodal Transcranial Direct Current Stimulation in Healthy Individuals
This study will separate study to investigate the effects of 1 mA, 1.5 mA, and 2 mA of 1) bilateral- and 2) cathodal tDCS on cortical activity and motor learning in healthy individuals
- Trial name
- NCT05929014
- Testing
- study 1) Active bilateral-tDCS, study 2) active cathodal-tDCS
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Schizophrenia, Insight Impaired
The Effects of Bimodal tDCS on Illness Severity, Insight, Functional Outcomes, Neurocognition and HRV in Schizophrenia
The study aimed to investigate the effects of bimodal anodal transcranial direct current stimulation (tDCS) over bilateral dorsolateral prefrontal cortex (DLPFC) on psychopathological symptoms, insight, psychosocial functioning…
- Conditions
- Schizophrenia, Insight Impaired, Psychotic Symptoms, Schizoaffective Disorder
- Trial name
- NCT03701100
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Stimulant Use, Alcohol Use Disorder
Neuromodulation and Cognitive Training for Substance Use Disorders
The relapsing nature of substance use disorder is a major obstacle to successful treatment. About 70% of those entering treatment will relapse within one year.
- Trial name
- NCT04426214
- Testing
- tDCS, Cognitive Training
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Stroke, Neurologic Disorder
Evaluation of Exoskeleton for Upper Limb Rehabilitation in Neurological Patients
Acquired cerebrovascular trauma is the third most common cause of disability worldwide, resulting in long-term disability, limitation of activities of daily living, and reduced social participation.
- Trial name
- PCP_EXOs (NCT05280431)
- Testing
- AGREE exoskeleton, FEXO exoskeleton, Conventional therapy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Casa di Cura Privata del Policlinico SpA
Depressive Disorder, Major Depressive Disorder, Healthy Volunteer
Exploring the Role of the Prefrontal Cortex in Decision-Making
The goal of this study is to examine whether high-definition transcranial direct current stimulation (HD-tDCS) can influence decision-making for emotionally valenced content in younger and older adults, with or without major…
- Conditions
- Depressive Disorder, Major Depressive Disorder, Healthy Volunteer, Aging
- Trial name
- NCT07080489
- Testing
- Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/F4, Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/ kathodal F4
- Where
- Switzerland
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Bern
Auditory Hallucination, Verbal
Effects of Transcranial Direct Current Stimulation (tDCS) on Persistent Auditory Verbal Hallucinations in Schizophrenia
Many individuals with schizophrenia struggle with auditory verbal hallucinations (AVHs). In some cases, these AVHs can be resistant to medication treatment.
- Trial name
- NCT04222582
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Schizophrenia, Cognition
Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic
This is a study of the effects of tDCS on smoking, craving for cigarettes, cognition, and psychiatric symptoms in schizophrenic patients who are current smokers or have a history of regular cigarette smoking.
- Conditions
- Schizophrenia, Cognition, Cigarette Smoking
- Trial name
- TDCSSCHIZ (NCT02128919)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Post-stroke Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Post-stroke Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of post-stroke cognitive impairment patients' cognitive function by altering the cortical…
- Trial name
- NCT03647319
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Alcohol Use Disorder (AUD), Alcohol Abuse
Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder
Background: Alcohol Use Disorder (AUD) is a complex psychiatric disorder, involving several brain areas and neurocircuits. Transcranial Direct Current Stimulation (tDCS) allows to stimulate superficial areas of brain using a weak…
- Conditions
- Alcohol Use Disorder (AUD), Alcohol Abuse, Alcohol Dependence, Alcohol-Related Disorders
- Trial name
- NCT04897295
- Testing
- Active transcranial Direct Current Stimulation
- Volunteers
- 30 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Aging, Mild Cognitive Impairment
Implication of Cognitive Reserve in Non-pharmacological Intervention Outcomes
Cognitive reserve (CR) is defined as the gradual accumulation of neural resources and their adaptability (i.e., efficiency, capacity, flexibility) due to genetic and/or lifelong environmental factors that mitigate the cognitive…
- Conditions
- Aging, Mild Cognitive Impairment, Dementia With Lewy Bodies
- Trial name
- NCT06563453
- Testing
- transcranial alternating current stimulation
- Where
- Czechia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Primary Progressive Aphasia
A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931
Primary Progressive Aphasia (PPA) is a syndrome due to different neurodegenerative disorders selectively disrupting language functions. PPA specialist care is underdeveloped.
- Trial name
- MAINSTREAM (NCT05730023)
- Testing
- Active tDCS, individualized language training
- Where
- 4 sites in Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Healthy
a-tDCS Combined With Aerobic Exercise in Healthy Individuals
The purpose of this study is to assess the effects on the exercise performance of anodal transcranial direct current stimulation combined with aerobic exercise in healthy individuals.
- Trial name
- NCT04211779
- Testing
- Real tDCS, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Marmara University
Parkinson Disease, Electroencephalogram
Predicting Outcomes From tDCS Intervention in Parkinson' Disease Using Electroencephalographic Biomarkers and Machine Learning Approach: the PREDICT Study Protocol
Parkinson's disease (PD) is a progressive and disabling neurodegenerative disease, clinically characterized by motor and non-motor symptoms.
- Conditions
- Parkinson Disease, Electroencephalogram, Transcranial Direct Current Stimulation
- Trial name
- PREDICT (NCT04819061)
- Testing
- tDCS Active
- Volunteers
- 56 people
- Sponsor
- Federal University of Paraíba
Schizophrenia, Cognitive Dysfunction
Transcranial Direct and Alternating Stimulation of the Prefrontal Cortex for Cognitive Improvement in Schizophrenia
The purpose of this study is to investigate different stimulation intensities and frequencies of transcranial direct and alternating current stimulation over the dorsolateral prefrontal cortex for cognitive improvement in…
- Trial name
- NCT05342727
- Testing
- transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS)
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
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