Clinical trials: Transcranial Direct Current Stimulation
Migraine
Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)
The purpose of this study is to determine whether a painless and noninvasive procedure called Transcranial Direct Current Stimulation (tDCS) can be an effective therapy for the treatment of migraine and migraine-associated pain.
- Trial name
- NCT00521196
- Testing
- DC Stimulator (Transcranial Direct Current Stimulator)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Beth Israel Deaconess Medical Center
Vegetative State, Minimally Conscious State
Multichannel tDCS to Reduce Hypertonia in Patients With Prolonged DOC
Previous studies showed that transcranial direct current stimulation (tDCS) transiently improves performance of motor function in stroke patients, as well as decrease muscle hypertonia.
- Conditions
- Vegetative State, Minimally Conscious State, Spasticity, Muscle, Disorder of Consciousness
- Trial name
- NCT03797573
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- University of Liege
Closed-loop Brain Stimulation
Closed-loop tES-non-invasive Stimulation
The goal of this study is to establish if non-invasive closed-loop neuromodulation is an effective approach to enhance cognitive function in healthy 18-40 years old volunteers.
- Trial name
- CLIBM (NCT07671079)
- Testing
- Transcranial low intensity focused ultrasound (FUS), transcranial electrical stimulation, Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Bipolar Disorder, Schizo Affective Disorder
Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation
Mania is a core symptom of bipolar disorder involving periods of euphoria. Decreased inhibitory control, increased risk-taking behaviors, and aberrant reward processing are some of the more recognized symptoms of bipolar disorder…
- Trial name
- NCT05445466
- Testing
- High-Definition Transcranial Electrical-Current Stimulation, High-Definition Transcranial Alternate-Current Stimulation, High-Definition Personalized Beta-Gamma Electrical Stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy Participants
The Effects of Cathodal tDCS on Muscle Strength in Healthy Adults
To investigate the effects of different intensity of cathodal tDCS on muscle strength in healthy adults.
- Trial name
- NCT04672122
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy
Conventional or High Definition tDCS to Enhance Implicit Motor Sequence Learning in Healthy Young Adults?
Implicit motor sequence learning (IMSL) is a form of cognitive function that is known to be directly associated with motor function.
- Trial name
- NCT04600531
- Testing
- 1x1 Low Intensity Transcranial Direct Current Stimulation (tDCS), 4x1 Multichannel Stimulation Adapter for High Definition Transcranial Direct Current Stimulation (HD tDCS)
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Anorexia in Adolescence
New Treatment Perspectives in Adolescents With Anorexia Nervosa: the Efficacy of Non-invasive Brain-directed Treatment
The present randomized, double blind, placebo-controlled trial aims at evaluating the efficacy of a tDCS treatment in improving the clinical outcome of adolescents with AN and investigate brain mechanisms acting in AN.
- Trial name
- NCT05674266
- Testing
- AN Active tDCS
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Healthy
Is Nociceptive Processing Evoked by Heat Homeostatically Regulated: A Contact-heat Evoked Potentials Study
Homeostatic plasticity is a mechanism that stabilizes neuronal activity to prevent excessive nervous system excitability. This mechanism can be investigated in humans by applying two blocks of non-invasive brain stimulation, such…
- Trial name
- NCT06197529
- Testing
- Homeostatic Plasticity, Topical alone (Capsaicin 8% Patch)
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Aphasia
Effect of Anodal Transcranial Direct Current Stimulation (tDCS) Over the Right-hemisphere on Picture Naming in Chronic Aphasia
There are two opposing hypotheses, namely the interference and laterality-shift hypotheses, regarding the role of the right hemisphere (RH) in language recovery following a left hemisphere damage.
- Trial name
- NCT05471570
- Testing
- tDCS stimulation
- Volunteers
- 4 people
- Sponsor
- The University of Hong Kong
Fibromyalgia
Occipital Transcranial Direct Current Stimulation in Fibromyalgia
The aim of this study is to investigate whether transcranial direct current stimulation is effective in the treatment of fibromyalgia related pain. The study provides a placebo arm and the design is a cross-over design.
- Trial name
- NCT00947622
- Testing
- Transcranial direct current stimulation
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- University Hospital, Antwerp
Chronic Widespread Pain, Fibromyalgia (FM)
The Added Value of Transcranial Direct Current Stimulation (tDCS) During Exercise for People With Chronic Widespread Pain
Many people with chronic widespread pain (CWP) feel more pain and fatigue after exercise. This makes it hard to stay active. Unfortunately, the investigators do not fully understand why this happens and how to prevent it.
- Trial name
- NCT07212829
- Testing
- Active tDCS, Aerobic exercise
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cognitive Decline, Healthy Aging
Non-invasive Brain Stimulation and Strategic Memory Training
Physiological aging is often associated with memory function decline. Recently, the use of transcranial direct current stimulation (tDCS), a type of non-invasive brain stimulation, has been combined with adaptive working memory…
- Trial name
- StMe-tDCS (NCT05929872)
- Testing
- Non-invasive brain stimulation
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Stroke
Randomized Trial of Transcranial Theta-burst Stimulation and Transcranial Direct Current Stimulation
Background: Stroke is a leading cause of adult disability. Non-invasive brain stimulation can induce significant and sustained improvements in functional outcome.
- Trial name
- NCT02031107
- Testing
- cTBS, cathodal tDCS
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Adrian Guggisberg
Transcranial Direct Current Stimulation (tDCS)
Intensity-Dependent Effects of 4-week Transcranial Direct Current Stimulation on Motor Learning in Healthy Young Adults
The goal of this clinical trial is to investigate the effects of different intensities of transcranial direct current stimulationover primary motor cortex on motor learning in healthy adults.
- Trial name
- NCT07089069
- Testing
- 3 mA transcranial direct current stimulation, 2 mA transcranial direct current stimulation, 1 mA transcranial direct current stimulation
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Parkinson Disease
Speech and Voice Outcomes Following HD-tDCS Over the Left SMA
Pharmaceutical and neurosurgical treatments reliably ameliorate the cardinal motor symptoms in PD but, they often yield inconsistent outcomes for speech and voice disorders, with some studies showing exacerbation of pre-treatment…
- Trial name
- NCT06245070
- Testing
- Active transcranial direct current stimulation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Multiple Sclerosis, Neurological Disorder
Cognitive Remediation Augmented With Transcranial Direct Current Stimulation (tDCS)
The proposed study will test the feasibility and tolerability of transcranial direct current stimulation (tDCS) added to a cognitive remediation program in n=100 adults.
- Trial name
- NCT03049969
- Testing
- tDCS stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Fibromyalgia (FM)
EEG Prediction and Clinical Efficacy of tDCS in Fibromyalgia.
The purpose of this randomized controlled trial is to investigate the non-inferiority, and possible superiority, of a high-dose home-based tDCS protocol compared with a conventional home-based protocol, and to assess its…
- Trial name
- FM-TDCS-PREDIC (NCT07583056)
- Testing
- High-dose home-tDCS M1, Conventional home-tDCS, High-dose home-tDCS DLPFC
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Ionclinics & Deionic SL
Stroke
Short Term Effects of Anodal Cerebellar vs Anodal Cerebral Transcranial Direct Current Stimulation in Stroke Patients
To compare the effect of anodal cerebellar Transcranial Direct Current Stimulation (tDCS) vs anodal cerebral tDCS on balance, mobility and cognition in stroke patients in stroke patients
- Trial name
- NCT05115851
- Testing
- Anodal tDCS cerebellar stimulation group, Anodal tDCS cerebral (M1) stimulation group
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Schizophrenia
Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia
The aim of this study is to evaluate the feasibility and efficacy of transcranial alternating current stimulation (tACS) as an add-on treatment for auditory hallucinations in refractory schizophrenia.
- Trial name
- NCT05282329
- Testing
- Transcranial alternating Current Stimulation (tACS)-active
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Anding Hospital
Phantom Limb Pain
Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response
The investigators have designed a pragmatic trial of home-based transcranial direct current stimulation (tDCS) for phantom limb pain (PLP), the PLP-EVEREST trial (PLP-EffectiVEness pRagmatic Stimulation Trial) to test a portable…
- Trial name
- PLP-EVEREST (NCT05188183)
- Testing
- M1 anodal home-based tDCS, Somatosensory Training, Usual Care
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Spaulding Rehabilitation Hospital
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