Clinical trials: Transcranial Direct Current Stimulation
Hemiparetic Stroke
Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments
Non-invasive, non-pharmaceutical technologies that augment routine clinical practice for brain diseases and manage chronic symptoms have advanced rapidly over the past two decades.
- Trial name
- NCT07599774
- Testing
- High-definition transcranial direct stimulation: optimal, Modified constraint-induced movement therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Carle Foundation Hospital
Fibromyalgia
Effects of Direct Transcranial Current Stimulation on Central Neural Pain Processing in Fibromyalgia
The main goal of this Collaborative Proposal is to investigate biochemical, functional, and structural neuroimaging changes following non-invasive brain stimulation in patients with chronic widespread pain: fibromyalgia (FM).
- Trial name
- NCT01745003
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Michigan
Premature Ejaculation, Sexual Dysfunction
Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Using Brain Mapping and Cognitive ERPs, the investigatos have searched for a Brain Networks involved during Inhibitory Control in Lifelong Premature Ejaculation (LPE) participants.
- Trial name
- LPE (NCT04850703)
- Testing
- Transcranial Radom Noise Stimulation, Take Dapoxetine, Compare LPE EEG endophenotype between participants and healthy controls
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Moises Domingo
Spinocerebellar Ataxia Type 3, Multiple System Atrophy-cerebellar Type
Treatment of Transcranial Alternating Current Stimulation（tACS）on Cerebellar Ataxia
This is a longitudinal, triple-blind, randomized-controlled, prospective interventional study assessing patients with cerebellar ataxia, including spinocerebellar ataxia type 3 (SCA3) and multiple system atrophy-cerebellar type…
- Trial name
- NCT05557786
- Testing
- Transcranial Alternating Current Stimulation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Parkinson's Disease
ParkinStim: Transcranial Direct Current Stimulation for Parkinson's Disease
The purpose of this study is to evaluate the effects of transcranial direct current stimulation (tDCS) on patients with Parkinson's disease during sleep.
- Trial name
- ParkinStim (NCT02125383)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Brain Tumor
Prehabilitation, Rehabilitation and Comprehensive Approach to the Sequelae of Brain Tumors
The goal of the present pilot single-cohort feasibility trial is to investigate the feasibility and understand potential mechanisms of efficacy for Neuromodulation-Induced Cortical Prehabilitation (NICP) in adults with brain…
- Trial name
- PREHABILITA (NCT05844605)
- Testing
- Non-invasive neuromodulation (TMS and/or tDCS)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Institut Guttmann
Post-stroke Aphasia
Neurostimulation for the Treatment of Post-Stroke Aphasia
The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.
- Trial name
- NCT05194566
- Testing
- tACS
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- QVITI S.A.
Healthy
Cerebellar tDCS on Motor Learning of Healthy Individuals
A crossover trial with healthy volunteers will be conducted. Three sessions will be performed with at least 48 hours washout period to minimize carry-over effects.
- Trial name
- NCT02557841
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Placebo Effect, Mindfulness
Interactions Between Placebo Effects and Mindful Awareness State
In this experiment,the investigators study the effects of interpersonally induced placebo effects and a mindful awareness induction on negative affect.
- Conditions
- Placebo Effect, Mindfulness, Pain, Transcranial Direct Current Stimulation (tDCS)
- Trial name
- NCT07108101
- Testing
- tDCS stimulation (real), Mindful state induction, No minfulness induction
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Best Comfort and Lowest Skin Irritation
Safety and Tolerability of Transcranial Direct Current Stimulation (tDCS)
Testing safety and tolerability of transcranial direct current stimulation (2 mA, 20 minutes) in four different protocols: saline-soaked sponges electrode with electrode gel tap-water-soaked sponges tap-water-soaked-sponges +…
- Trial name
- NCT01148212
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Inflammatory Bowel Disease
Association of Functional Changes in the Brain and the Perception of Pain in Patients With Chronic Inflammatory Bowel Diseases (IBD)
In the study the investigators aim to test whether transcranial direct current stimulation (tDCS)-induced pain reduction is in association with functional changes in the brain measured with magnetic resonance imaging (MRI) in…
- Trial name
- NCT02433470
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Chronic Pain
Motor System Activation With Transcranial Direct Current Stimulation and Physical Exercise to Reduce Pain in Elderly
Physical exercises are known to reduce chronic pain in elderly individuals by activating the motor system. However, it seems that exercises are not effective for everyone.
- Trial name
- NCT04332939
- Testing
- transcranial direct current stimulation, Physical exercise
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- Université de Sherbrooke
Impulsive Behavior, Suicidal Impulses
tDCS Applied to the OFC: Effects on Decision-Making and Impulse Control
In this study the investigators aim to assess whether transcranial direct current stimulation (tDCS; a safe and non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex…
- Trial name
- NCT01805401
- Testing
- Transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Brain Stimulation, Alzheimer Disease
Transcranial Alternating Current Stimulation (TACS) for Sleep Disturbances in Neurocognitive Disorders Due to Alzheimer's Disease
Background: Sleep disturbances are highly prevalent in ageing population and patients with age-related neurodegenerative diseases, which severely affect cognition and even lead to accumulated amyloid-β (Aβ).
- Conditions
- Brain Stimulation, Alzheimer Disease, tACS, Sleep Disturbance
- Trial name
- NCT05544201
- Testing
- High-definition transcranial current stimulation
- Where
- Hong Kong
- Volunteers
- 99 people
- Sponsor
- Chinese University of Hong Kong
Depressive Disorder, Generalized Epilepsy
Transcranial Direct Current Stimulation (tDCS) in Children and Adolescents With Epilepsy and Depression
The proposed study seeks to obtain preliminary signal of the tolerability and efficacy of transcranial direct current stimulation (tDCS) for depressive symptoms in a sample of adolescents with depression and epilepsy.
- Trial name
- NCT03368469
- Testing
- transcranial direct current stimulation
- Where
- United States
- Sponsor
- Mayo Clinic
Learning; Lack of (Specific)
Predictors of Probabilistic Selection Task Performance
The project aims to investigate whether tDCS has an effect on reward and punishment learning sensitivity. Further, whether tDCS will modulate extraversion and impulsivity personality traits, and eye-blink-rate's effect on…
- Trial name
- NCT04798105
- Testing
- Effects of tDCS of dlPFC on Probabilistic Selection Task
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Refractory Epilepsy, Focal Seizure
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers…
- Conditions
- Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures
- Trial name
- NCT04770337
- Testing
- STARSTIM device
- Where
- 32 sites in United States, Belgium and 2 more
- Volunteers
- 127 people
- Sponsor
- Neuroelectrics Corporation
Transcranial Direct Current Stimulation, Post Operative Pain
Effectiveness of Transcranial Direct Current Stimulation for TKR
Transcranial direct current stimulation (tDCS) is a technique of noninvasive cortical stimulation allowing significant modification of brain function used.
- Trial name
- NCT03898245
- Testing
- apply tDCS
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- SMG-SNU Boramae Medical Center
Sleep
The Effect of Pre-Frontal tDCS on Sleep Propensity During an Afternoon Nap: RCT
Transcranial Direct Current Stimulation (tDCS) is a safe, non-invasive brain stimulation technology that has demonstrated the ability to temporarily increase or decrease activity in specific regions of the brain.
- Trial name
- NCT02176785
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
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