Clinical trials: Transcranial Direct Current Stimulation, completed
Epilepsy
Evaluation of Direct Effects of Electric Fields on Brain
Transcranial current stimulation (tCS), a safe, tolerable technique employing weak currents (~ 1 mA) applied to the scalp, has been shown to be a promising technique in alleviating seizures in focal epilepsy patients.
- Trial name
- GALVANI PS-2 (NCT05250713)
- Testing
- Transcranial stimulation
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Stroke, Acute
Effect of tDCS on Motor Functions and Brain Activity in Acute Stroke Patients
This study aims to investigate the effects of anodal tDCS combined with conventional physical therapy for 5 consecutive sessions on motor functions and brain activity in acute stroke patients at immediate and 1-month follow-up.
- Trial name
- NCT04578080
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Schizophrenia, Schizoaffective Disorder, Mixed Type
Online HD-tDCS Over the Left DLPFC During a Working Memory Task for Treating Negative Symptoms of Schizophrenia
In this randomized double-blind trial, the investigators aim to investigate whether online high definition transcranial direct current stimulation (HD-tDCS) over the left dorsolateral prefrontal cortex (DLPFC) during a working…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Mixed Type, Negative Symptoms in Schizophrenia
- Trial name
- NCT05582980
- Testing
- HD-tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Pain Management
BreEStim and tDCS for Neuropathic Pain Management - Healthy Subjects
This study looks at the effect of combined breathing-controlled electrical stimulation (BreEStim) and transcranial direct current stimulation (tDCS) on neuropathic pain after spinal cord injury, amputation, or brain injury.
- Trial name
- NCT03302780
- Testing
- BreEStim, tDCS active
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Depression
Adjunctive Transcranial Direct Current Stimulation for Cognition in Major Depression
People who have depression often have symptoms besides sad mood. Cognitive symptoms, such as poor memory, concentration, and decision making, are associated with disability in many spheres of life, and these symptoms often…
- Trial name
- aTDCS (NCT00760097)
- Testing
- Transcranial direct stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, Los Angeles
Primary Progressive Aphasia, PPA
Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy
People with Primary Progressive Aphasia (PPA) are is a debilitating disorder characterized by the gradual loss of language functioning, even though cognitive functioning is relatively well preserved until the advanced stages of…
- Trial name
- NCT03728582
- Testing
- Active tDCS plus Speech-Language Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Stuttering, Developmental, Aphasia, Primary Progressive
Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
Persistent developmental stuttering affects more than three million people in the United States, and it can have profound adverse effects on quality of life.
- Trial name
- NCT05437159
- Testing
- Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords
- Where
- 3 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Attention Deficit Disorder With Hyperactivity, Neurodevelopmental Disorders
tES Modalities for the Treatment of ADHD
This project investigates the efficacy of transcranial electrical stimulation (tES) modalities, specifically transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), for treating…
- Trial name
- NCT06974136
- Testing
- transcranial electrical stimulation
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Anxiety State
A Functional Magnetic Resonance Imaging Investigation of Transcranial Direct Current Stimulation
This study evaluates the effect of frontal cortex transcranial direct current stimulation (tDCS) on the neural correlates of threat processing in healthy volunteers with a high level of trait anxiety.
- Trial name
- NCT03623815
- Testing
- transcranial direct current stimulation
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Stroke, Aphasia
Effects of Transcranial Direct Current Stimulation (tDCS) on Brain Organization and Naming in Aphasic Patients.
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) allows to induce, in a non-invasive way, a transient inhibitory or excitatory neuromodulation of a given cerebral region and to obtain a very focused cortical…
- Trial name
- NCT05570578
- Testing
- HD-tDCS
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Adrian Guggisberg
Ankle Injuries and Disorders
Balance Training With tDCS for CAI
The purpose of this research study is to examine the efficacy of non-invasive brain stimulation in addition to balance exercise for chronic ankle instability (CAI), a condition that develops following an initial ankle sprain…
- Trial name
- NCT04390048
- Testing
- Anodal tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Miami
Panic Disorder
The Effect Of Transcranial Direct Current Stimulation In Panic Disorder
The aim of the present study is to investigate the effect of prefrontal transcranial Direct Current Stimulation (tDCS) on clinical severity, attentional bias and interoceptive accuracy in panic disorder (PD).
- Trial name
- PDStim (NCT04160806)
- Testing
- Transcranial direct current stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Lennox-Gastaut Syndrome
Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study
Background: Lennox-Gastaut syndrome (LGS) is a severe childhood epileptic syndrome with high pharmacoresistance. The treatment outcomes are still unsatisfied.
- Trial name
- NCT02731300
- Testing
- tDCS
- Volunteers
- 22 people
- Sponsor
- Khon Kaen University
Stroke
Transcranial Direct Current Stimulation Combined Sensory Modulation Intervention in Chronic Stroke Patients
Background and purpose: About 30% of people with stroke suffered from severe long-term upper extremity （UE） motor impairment. Severe UE impairment, especially dysfunction of hand, can greatly impact stroke patients' daily living…
- Trial name
- NCT01847157
- Testing
- tDCS, Epidermis anesthesia, Repeated passive movement
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Healthy
Effect of Electrical Stimulation (DC Polarization) to the Brain on Memory
This study will test the effect of direct current (DC) brain polarization (the application of a very weak electrical current to the brain) on learning and memory.
- Trial name
- NCT00471107
- Testing
- DC brain polarization
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Osteo Arthritis Knee, Chronic Pain
Addition of Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to an Education and Exercise Program in Subjects With Chronic Pain Due to Knee Osteoarthritis
Knee osteoarthritis has a very high prevalence in the population over 50 years of age. Patients with osteoarthritis often suffer from chronic pain that becomes disabling, affecting both quality of life and mental and physical…
- Trial name
- NCT05138471
- Testing
- transcranial direct current stimulation (tDCS), TENS, Exercise and General Education
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Universidad de Murcia
Cerebral Palsy, Perinatal Stroke
Single-session tDCS in Cerebral Palsy
The goal of this study is to characterize individual responses to a single application of transcranial direct current stimulation (tDCS) in children with unilateral cerebral palsy (UCP), and to test which electrode configuration…
- Conditions
- Cerebral Palsy, Perinatal Stroke, Periventricular Leukomalacia
- Trial name
- NCT03635775
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Psychosis, Schizophrenia
Targeting Individual Alpha Frequencies to Enhance Perceptual Timing
This is a single-blind randomized within-subject crossover design study that will be conducted in 2 phases. In Phase 1, up to 50 participants, after signing informed consent and determining eligibility, will undergo a baseline…
- Conditions
- Psychosis, Schizophrenia, Schizo Affective Disorder
- Trial name
- NCT04856657
- Testing
- Transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pain
High Definition Transcranial Direct Current Stimulation Motor Cortex Versus Insula
Brain stimulation is a technique that can alter cortical function and thus be suitable for treating pain. This is especially when pain is chronic and associated with functional and even structural reorganization of the central…
- Trial name
- NCT03216707
- Testing
- HD tDCS active motor cortex, HD tDCS active insula cortex, Capsaicin cream
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stroke
Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery
The purpose of this study is to investigate whether benefits of training the affected hand in patients with stroke can be improved by combining training with a painless, noninvasive technique called Transcranial Direct Current…
- Trial name
- NCT01539096
- Testing
- tDCS: noninvasive brain stimulation, Constraint induced movement therapy (CIMT)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic