Clinical trials: Transcranial Direct Current Stimulation, completed
Aging
Neural Underpinnings of Turning
Older adults and stroke survivors often have difficulty performing complex walking tasks, due in part to changes in the brain. One task often overlooked is turning, which can lead to injury when performed poorly.
- Trial name
- NCT05475236
- Testing
- Experimental: Locomotor Learning
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, So Stated
Effects of Brain Stimulation During a Daytime Nap on Memory Consolidation in Patients With Mild Cognitive Impairment
The beneficial effect of nocturnal as well as daytime sleep on memory consolidation is well-documented in young, healthy subjects.
- Trial name
- NCT01782365
- Testing
- 0,75 Hz stimulation
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Charite University, Berlin, Germany
Mobility Limitation, Cognitive Impairment
Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study
Loss of mobility and cognitive ability are serious conditions that threaten the independence of older adults. The objective of this study is to initiate a line of research to develop a novel therapeutic intervention to enhance…
- Trial name
- NCT03122236
- Testing
- Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Active Transcranial Direct Current Stimulation (Active tDCS)
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Boxing, Athletic Performance
Transcranial Direct Current Stimulation Promotes Punching and Movement Speed in Elite Male Boxers
This study investigates whether transcranial direct current stimulation (tDCS), a safe and non-invasive brain stimulation technique, can improve punching and movement speed in elite male boxers.
- Conditions
- Boxing, Athletic Performance, tDCS
- Trial name
- NCT07862166
- Testing
- Anodal tDCS over M1, Anodal tDCS over DLPFC
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Stroke
Transcranial Direct Current Stimulation on the Risk of Falls and Lower Limb Function for Acute Stroke
Transcranial direct current stimulation (tDCS) has shown promising results in the modulation of cortical excitability and the promotion of neuronal plasticity after stroke.
- Trial name
- NCT02422173
- Testing
- Anodal transcranial direct current stimulation, Cathodal transcranial direct current stimulation, Bilateral transcranial direct current stimulation
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Traumatic Brain Injury, Post Concussive Symptoms
Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury
Patients with mild-moderate traumatic brain injury (TBI) sustained between 3 months and 5 years ago with prolonged postconcussive symptoms will be recruited.
- Conditions
- Traumatic Brain Injury, Post Concussive Symptoms, Depression, Executive Dysfunction
- Trial name
- NCT02613936
- Testing
- Anodal tDCS, Cognitive training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of New Mexico
Aging
Augmenting Cognitive Training In Older Adults
A two-phase adaptive randomized clinical trial will examine the individual and combined impact of pairing cognitive training with transcranial direct current stimulation (tDCS).
- Trial name
- ACT (NCT02851511)
- Testing
- Cognitive Training, tDCS (active stimulation), Educational Training
- Where
- 3 sites in United States
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- University of Florida
Neurofibromatosis 1
Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1
Intellectual impairment, particularly working memory deficits are a significant cause of morbidity in children with Neurofibromatosis type (NF1) with long-term implications on academic and occupational functioning.
- Trial name
- NCT04991428
- Testing
- Transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University of Manchester
Schizophrenia
Target Engagement of the Early Auditory Processing Network by Transcranial Direct Current Stimulation (tDCS)
Individuals with schizophrenia have difficulties in functioning in the community. No one really knows what factors determine how well patients manage in the real world.
- Trial name
- NCT02620267
- Testing
- tDCS Stimulation
- Volunteers
- 14 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Impulsive Behavior, Inhibition
Inhibition Transcranial Random Noise Stimulation
Inhibition control deficits is a major risk factor in the transition to the act in suicidal patients. Neuroimaging studies have shown that this failure was associated with hypoactivity in the prefrontal cortex (PFC), a brain area…
- Trial name
- inhibistim (NCT02717260)
- Testing
- transcranial random noise stimulation (tRNS) (Starstim)
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Major Depressive Disorder
Effect of Self-administered tDCS in Patients With MDD
In this randomized, single-blinded clinical trial, 58 patients with major depressive disorder were assigned to active and sham tDCS stimulation groups in a 1:1 ratio, and treatment responses were evaluated biweekly over six weeks.
- Trial name
- NCT04543123
- Testing
- tDCS treatment, Antidepressant Drug(escitalopram)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Jeong-Ho Chae
Postural; Defect
Combined Effects of Transcranial Direct Current Stimulation on Postural Control in Elderly
The current study aims to determine the effects of combination stimulation (M1 Cortex+ Cerebellum) along with balance training (X-box with Kinect) on postural control in elderly population and to compare the combined stimulation…
- Trial name
- NCT06757088
- Testing
- M1 Stimulation Group, Cerebellar Stimulation Group (CbSG), M1 + Cerebellar Stimulation Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Schizophrenia
tDCS to Enhance Cognitive Training in Schizophrenia
The primary aim for the study is to determine whether transcranial direct current stimulation (tDCS) enhances training gains on cognitive training (CT) tasks.
- Trial name
- NCT01733602
- Testing
- transcranial direct current stimulation
- Where
- Australia
- Volunteers
- 52 people
- Sponsor
- The University of New South Wales
Stress Response
Investigating Stress-Induced Dopamine Release: a fMRI-PET Study
The stress response is mediated by the activation of the hypothalamo-pituitary-adrenal axis and the sympathetic nervous system, leading to glucocorticoid and catecholamines release respectively.
- Trial name
- ISIDORE (NCT05825677)
- Testing
- tDCS actif
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Primary Progressive Aphasia
Treating Primary Progressive Aphasia (PPA) Using tDCS
This is a double-blind, sham-controlled, crossover study in which subjects with the non-fluent/agrammatic and semantic variants of primary progressive aphasia (naPPA and svPPA, respectively) will undergo language testing and…
- Trial name
- NCT04566731
- Testing
- Transcranial Direct Current Stimulation (tDCS), Modified Contraint-Induced Language Therapy (mCILT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pennsylvania
COVID-19
Transcranial Direct Stimulation for Persistent Fatigue Treatment Post-COVID-19
Fatigue is common and disabling in patients with post-COVID syndrome. There is no treatment available at this moment, and fatigue has important consequences.
- Trial name
- STIMULATECOVID (NCT05252481)
- Testing
- Active tDCS
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Hospital San Carlos, Madrid
Sjogren's Syndrome
tDCS for Fatigue in Sjogren's Syndrome
Sjogren's Syndrome (SS) is an autoimune disease of unknown etiology characterized by lymphocytic infiltration of the exocrine glands and other organs.
- Trial name
- NCT04119128
- Testing
- Active Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Federal University of São Paulo
Neuropathic Pain, Spinal Cord Injury
The Effects of Transcranial Direct Current Stimulation on Central Pain in Patients With Spinal Cord Injury
The purpose of this study is to evaluate the analgesic effect of transcranial direct current stimulation (tDCS) applied on motor cortex in patients with spinal cord injury who have chronic neuropathic pain.
- Trial name
- NCT01781065
- Testing
- transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Seoul National University Bundang Hospital
Dysphoria
Effects of Transcranial Direct Current Stimulation on Reward Learning in Subclinical Depression.
This project will test whether transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) can alter reward learning behaviour in subclinical depression.
- Trial name
- NCT03393312
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oxford