Clinical trials: Transcranial Direct Current Stimulation
Depression, Anxiety and Fear
Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression
Over 50% of patients with major depressive disorder (MDD) do not respond to initial treatment and relapse is common. In particular, comorbid depression and anxiety disorders are associated with more treatment resistance.
- Trial name
- NCT04948944
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Transcranial Direct Current Stimulation to Improve Gait for Breast Cancer Survivor's Who Received Taxene and/or Platinum Chemotherapy
This clinical trial tests the effect of transcranial direct current stimulation (tDCS) to improve gait in older breast cancer survivors who received taxane and/or platinum chemotherapy.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT07864792
- Testing
- Survey Administration, Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan Rogel Cancer Center
Fatigue
Impact of Transcranial Direct Current Stimulation on Fatigability and Fatigue Induced by a Selective Attention Task
This research project is focusing on changes in mental fatigue due to transcranial direct current stimulation (tDCS) in healthy individuals.
- Trial name
- NCT02840214
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parkinson Disease (PD), Gait Disorders
Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Gait and Balance in Parkinson's Disease
Parkinson's disease can cause slow or unsteady walking and balance problems that raise the risk of falls. This study will test whether adding a gentle, non-invasive brain stimulation called transcranial direct current stimulation…
- Conditions
- Parkinson Disease (PD), Gait Disorders, Postural Balance
- Trial name
- tDCS+NW-PD (NCT07381907)
- Testing
- Transcranial Direct Current Stimulation (tDCS), active, Standardized Nordic Walking program
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Metodista de Piracicaba
Healthy
Establish the Role of Premotor and Motor Cortices in tDCS-facilitated Speech Motor Learning
Groups of unimpaired participants will all receive speech motor training of nonwords, and six tDCS conditions will be compared: anodal tDCS over speech motor regions; cathodal tDCS over speech motor regions; anodal tDCS over left…
- Trial name
- NCT05804344
- Testing
- Anodal speech motor tDCS, Cathodal speech motor tDCS, Anodal IFG tDCS
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- New York University
Spinal Cord Injuries, Tetraplegia
Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function
Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
- Trial name
- NCT04777149
- Testing
- transcranial Random Noise Stimulation (tRNS), transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Shepherd Center, Atlanta GA
Aging, Accidental Falls
Feasibility of Home-based tES for Older Adults at Risk of Falling
In this project, the investigators propose to demonstrate the feasibility of remotely-monitored, caregiver (or spouse)-administered, home-based tES (transcranial electrical stimulation) intervention to improve mobility in…
- Trial name
- NCT04732533
- Testing
- tES (transcranial electrical stimulation)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Chronic Stroke
tDCS and CO-OP in Chronic Stroke
This project seeks to evaluate the acceptability feasibility, practicality feasibility, and preliminary effect of combining transcranial direct current stimulation (tDCS) and metacognitive strategy training (MCST) in individuals…
- Trial name
- NCT04617548
- Testing
- tDCS and CO-OP Group
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obsessive-Compulsive Disorder
Enhancement of Therapeutic Learning in OCD Using tDCS
Psychiatric disorders characterized by pathological fear and anxiety are common and often disabling. Despite their limitations, exposure therapies are among the most efficacious treatments for these disorders.
- Trial name
- NCT03572543
- Testing
- tDCS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Attention Deficit Hyperactivity Disorder
TDCS for the Treatment of Inattention Symptoms in Adult ADHD Patients
This study aims at evaluating the efficacy and safety of a home-based tDCS device when compared to a sham stimulation for improving attention in adult ADHD patients.
- Trial name
- TUNED (NCT04003740)
- Testing
- Home-based transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Cognitive Dysfunction
Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery
Postoperative cognitive dysfunction (POCD) is a contrary event observed between 20 to 83%, especially on elderly and patients submitted to cardiac surgery.
- Trial name
- tDCS (NCT02549560)
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- University of Sao Paulo
Parkinson Disease
Transcranial Direct Current Stimulation of the Primary Motor Cortex to Treat Levodopa-induced Dyskinesias
The main objective of the study is to evaluate the efficacy of 10 sessions of transcranial direct current stimulation of the primary motor cortex to reduce levodopa-induced dyskinesia
- Trial name
- NCT05752240
- Testing
- Transcranial direct current stimulation
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stroke
Transcranial Direct Current Stimulation (tDCS) in Chronic Stroke Recovery
The hypothesis of this study is that different subgroups of stroke will respond differently to direct current stimulation.
- Trial name
- NCT01014897
- Testing
- tDCS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Texas Southwestern Medical Center
Vegetative State, Minimally Conscious State
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- tDCS in DOC (NCT01673126)
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University of Liege
Epilepsy
High Definition Cathodal Transcranial Direct Current Stimulation for Treatment of Refractory Partial Onset Epilepsy
High-Definition transcranial Direct Current Stimulation (HD tDCS) Genuine cathodal HD-tDCS will be delivered through High-Definition electrodes that will be arranged on the skull according to a 4x1-ring configuration with the…
- Trial name
- HD-TDCS (NCT02264652)
- Testing
- HD Transcranial Direct Stimulation
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Pain, Chronic
Effects of Transcranial Direct Current Stimulation on Pain Control in Chronic Painful Total Knee Arthroplasty
The TSEF-PTG study aims to evaluate the effects of transcranial Direct Current Stimulation (tDCS) and exercise versus sham tDCS (placebo) and exercise on pain control in chronic painful total knee arthroplasty (TKA) patients.
- Trial name
- TSEF-PTG (NCT04579952)
- Testing
- transcranial Direct Current Stimulation
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Istituto Ortopedico Rizzoli
Trigeminal Neuropathic Pain
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain
The main goal of this study to integrate techniques producing images of the brain (also called neuroimaging techniques) with non-invasive brain stimulation to investigate factors that may be associated with chronic pain in…
- Trial name
- NCT03003715
- Testing
- PET Scans, transcranial direct current stimulation (tDCS), MRI
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depressive Disorder (MDD)
Non-invasive Brain Stimulation in Subjects with Major Depressive Disorder
Introduction The study involves the recruitment of outpatients suffering from Major Depressive Disorder (MDD), diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).
- Trial name
- NIBS_tDCS (NCT06714643)
- Testing
- Active tDCS
- Volunteers
- 105 people
- Sponsor
- Carmen Concerto
Pain
Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography…
- Trial name
- NCT06968689
- Testing
- transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
tDCS, Sham tDCS
tdCS Combined With Treadmill Training in Patients With Multiple Sclerosis
This clinical trial aims to evaluate the therapeutic effectiveness of transcranial direct current stimulation (tDCS), a non-invasive technique that modulates cortical excitability, in combination with gait training in patients…
- Trial name
- TDCS (NCT06986278)
- Testing
- tDCS
- Where
- 2 sites in Spain
- Volunteers
- 78 people
- Sponsor
- University of Castilla-La Mancha
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