Clinical trials: Transcranial Direct Current Stimulation
Stroke, Apraxia
Rehabilitating (Stroke-induced) Apraxia With Direct Current Stimulation
The objective of the clinical trial is to investigate whether weak transcranial direct current stimulation (tDCS) can ameliorate the motor cognitive deficit apraxia during stroke rehabilitation.
- Trial name
- RAdiCS (NCT03185234)
- Testing
- anodal tDCS
- Where
- 2 sites in Germany
- Volunteers
- 117 people
- Sponsor
- University of Cologne
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Stroke
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only one region.
- Trial name
- NCT05638464
- Testing
- multisite HD-tDCS EMG-driven robot hand
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mild Cognitive Impairment
Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation
The overall goal of this project is to improve cognitive control abilities in adults with mild cognitive impairment (MCI) through a form of non-invasive brain stimulation, transcranial alternating current stimulation (tACS).
- Trial name
- NCT04647032
- Testing
- Transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Eating Behavior
Effect of tDCS Montage on Measures of Appetite
The aim is to validate a new sham (control) method for use in transcranial direct current stimulation (tDCS) that is less discernible to participants from the real condition.
- Trial name
- NCT03396549
- Testing
- real tDCS
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Knee Arthroplasty, Transcranial Direct Current Stimulation
Knee Arthroplasty Recovery With Transcranial Direct Current Stimulation
Total knee arthroplasty (TKA) is widely performed to reduce pain from advanced osteoarthritis, yet many patients experience severe postoperative pain and up to 25-44% develop chronic postsurgical pain (CPSP).
- Conditions
- Knee Arthroplasty, Transcranial Direct Current Stimulation, Pain, Postoperative
- Trial name
- KART (NCT07351578)
- Testing
- Active tDCS Stimulation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Women's College Hospital
Traumatic Brain Injury, Post Concussive Symptoms
Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury
Patients with mild-moderate traumatic brain injury (TBI) sustained between 3 months and 5 years ago with prolonged postconcussive symptoms will be recruited.
- Conditions
- Traumatic Brain Injury, Post Concussive Symptoms, Depression, Executive Dysfunction
- Trial name
- NCT02613936
- Testing
- Anodal tDCS, Cognitive training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of New Mexico
Mild Cognitive Impairment
Effects of tDCS on Cognition in MCI: A RCT
MCI is considered an intermediate stage between normal cognitive aging and dementia. As such, improving cognitive functions of people with MCI may delay dementia onset.
- Trial name
- NCT05584748
- Testing
- transcranial direct current stimulation
- Volunteers
- 48 people
- Sponsor
- Tung Wah College
Multiple Sclerosis, MS
Evaluation of the Efficacy of Transcranial Direct Current Stimulation in Reducing Fatigue and Improving Quality of Life in Patients With Multiple Sclerosis: A Randomized Clinical Trial
The goal of this clinical trial is to evaluate whether the application of three 2-week cycles of tDCS combined with motor therapy is more effective in reducing fatigue in adult patients with multiple sclerosis, compared to the…
- Trial name
- tDCS (NCT06873464)
- Testing
- Three cycles of tDCS combined with motor tasks, Two cycles of tDCS combined with motor tasks
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- European University of Madrid
Stroke
Neuroregeneration Enhanced by Transcranial Direct Current Stimulation (TDCS) in Stroke
Testing the hypothesis that non-invasive brain stimulation by transcranial direct current stimulation (tDCS) combined with functional training in the subacute phase of first-ever stroke will enhance functional regeneration…
- Trial name
- NETS (NCT00909714)
- Testing
- DC-Stimulator to apply tDCS
- Where
- 11 sites in Austria, Germany and 1 more
- Volunteers
- 119 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Fetal Alcohol Spectrum Disorders
Cognitive Training and tDCS for Children With FASD
This is a randomized placebo-controlled trial of cognitive training with transcranial direct current stimulation (tDCS) for children and adolescents (ages 10 - 16 years) with prenatal alcohol exposure (PAE).
- Trial name
- NCT03361293
- Testing
- Active tDCS, Cognitive training
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Primary Dysmenorrhea
Efficacy of Transcranial Direct Current Stimulation for Severe Primary Dysmenorrhea
Primary Dysmenorrhea (PDM), defined as menstrual pain without discernable organic causes, is inexorably common in adolescent women, about 40-90% of women may suffer from it, and 20% of them can be severe in the context of being…
- Trial name
- NCT03594916
- Testing
- Active tDCS
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Schizophrenia
Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia
The aim of this study is to evaluate the feasibility and efficacy of transcranial alternating current stimulation (tACS) as an add-on treatment for auditory hallucinations in refractory schizophrenia.
- Trial name
- NCT05282329
- Testing
- Transcranial alternating Current Stimulation (tACS)-active
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Anding Hospital
Fibromyalgia (FM)
EEG Prediction and Clinical Efficacy of tDCS in Fibromyalgia.
The purpose of this randomized controlled trial is to investigate the non-inferiority, and possible superiority, of a high-dose home-based tDCS protocol compared with a conventional home-based protocol, and to assess its…
- Trial name
- FM-TDCS-PREDIC (NCT07583056)
- Testing
- High-dose home-tDCS M1, Conventional home-tDCS, High-dose home-tDCS DLPFC
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Ionclinics & Deionic SL
Cognitive Dysfunction ( MMSE < 24 )
Effects of tDCS on Cognitive Function in Older Adults With Subjective Cognitive Decline: Randomized Sham-Controlled Trial
This randomized, double-blind, sham-controlled clinical trial evaluates the effects of transcranial direct current stimulation (tDCS) using the Sooma Oy device on cognitive function in older adults with Subjective Cognitive…
- Trial name
- TDCSCOGSCDTRIA (NCT07531888)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma del Estado de Hidalgo
Stroke, Upper Extremity Paresis
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a person recover hand movement.
- Conditions
- Stroke, Upper Extremity Paresis, Hemiplegia
- Trial name
- NCT05866003
- Testing
- Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, CCFES with Occupational Therapy
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- MetroHealth Medical Center
Stroke
Short Term Effects of Anodal Cerebellar vs Anodal Cerebral Transcranial Direct Current Stimulation in Stroke Patients
To compare the effect of anodal cerebellar Transcranial Direct Current Stimulation (tDCS) vs anodal cerebral tDCS on balance, mobility and cognition in stroke patients in stroke patients
- Trial name
- NCT05115851
- Testing
- Anodal tDCS cerebellar stimulation group, Anodal tDCS cerebral (M1) stimulation group
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Phantom Limb Pain After Amputation
Preventing Chronification of Phantom Limb Pain Through Mirror Therapy in Conjunction With tDCS
Background: Most amputees experience phantom limb pain (PLP), for years after amputation. Virtually all PLP research to date has focused on the mechanisms of chronic PLP, ignoring the mechanisms of chronification.
- Trial name
- NCT07139483
- Testing
- Trans Direct-Cranial Stimulation (tDCS), Mirror therapy
- Where
- 3 sites in Israel
- Volunteers
- 108 people
- Sponsor
- University of Haifa
Healthy Volunteers
Neurophysiological Study of tDCS Effects in Healthy Volunteers
Transcranial direct current stimulation is a tool to modulate cortical excitability.
- Trial name
- tDCSHV (NCT02125422)
- Testing
- Cefaly tDCS
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Liege
Knee Replacement
Transcranial Direct Current Stimulation for Postoperative Pain in Knee Arthroplasty
The objective of this study is to detect the effect of trans-cranial direct current stimulation on postoperative pain and opioid consumption in total knee arthro-plasty patients.
- Trial name
- TDCSTKA (NCT02704182)
- Testing
- tDCS
- Volunteers
- 46 people
- Sponsor
- Assiut University
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