Clinical trials: Treatment as usual
Type 1 Diabetes Mellitus
Use of Continuous Glucose Sensors by Adolescents With Inadequate Diabetic Control
The incorporation of continuous glucose sensors (CGS) into management of type 1 diabetes in adolescence could improve treatment outcomes.
- Trial name
- CGM-Teens (NCT00945659)
- Testing
- Continuous Glucose Sensor, Standard Care, CGS + Behavior Therapy
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Nemours Children's Clinic
Perinatal Mental Health, Pregnancy Related
Mindfulness-Based Stress Reduction for Psycho-socially Vulnerable Pregnant Women.
The aim of the study is to address the need for a wider array of evidence-based and non-pharmacological options to improve mental health in a psycho-socially highly vulnerable group of pregnant women.
- Trial name
- NCT05300646
- Testing
- Prenatal mindfulness-based stress reduction
- Where
- 2 sites in Denmark
- Volunteers
- 238 people
- Sponsor
- University of Aarhus
Interpersonal Violence, Structural Violence
Strengthening the Connections to Opportunities for Prevention Engagement
The Strengthening the Connections to Opportunities for Prevention Engagement (SCOPE) project will create a pathway for children and families from the City of Hartford to connect with a Connecticut Children's Care Coordinator (CC)…
- Trial name
- SCOPE (NCT06442046)
- Testing
- Active Case Management, Treatment as usual
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Kevin Borrup
Adolescent Behavior, Adolescent - Emotional Problem
Teachers Leading the Front Lines - Adolescent
Purpose: The purpose of this research is to pilot test a novel, alternative, potentially sustainable system of teacher-delivered, task-shifted adolescent mental health care.
- Conditions
- Adolescent Behavior, Adolescent - Emotional Problem, Mental Health Issue, Psychosocial Functioning
- Trial name
- TeaLeaf-A (NCT06248203)
- Testing
- Tealeaf-Mansik Swasta (Tealeaf) as adapted for Adolescents, Enhanced Usual Care (EUC)
- Where
- India
- Volunteers
- 216 people
- Sponsor
- University of North Carolina, Chapel Hill
Sepsis
Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket Trial
PALETTE is a perpetual adaptive platform to efficiently study sepsis interventions within 'treatable traits' in all-ages patients enabling prompt evaluation of pandemic treatments.
- Trial name
- PALETTE (NCT06381661)
- Testing
- Tocilizumab, Baricitinib, Anakinra
- Where
- 19 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Childhood Asthma
Training Parents by Acceptance and Commitment Therapy for Managing Childhood Asthma Care
The purpose of this study is to examine whether a parental training program using group-based Acceptance and Commitment Therapy for childhood asthma care, is effective in reducing the children's unplanned health care services…
- Trial name
- NCT02405962
- Testing
- ACT, Control
- Where
- 3 sites in Hong Kong
- Volunteers
- 168 people
- Sponsor
- The Hong Kong Polytechnic University
Coronary Artery Disease, Acute Myocardial Infarction
Beta Blocker De-prescription Following Coronary Artery Bypass Graft Surgery (BEEFBURGER Trial).
Beta-blockers have the greatest cardiovascular impact in patients with reduced heart function/heart failure and in reducing the peri-operative risk of atrial fibrillation.
- Conditions
- Coronary Artery Disease, Acute Myocardial Infarction, Coronary Artery Stenosis, ST Elevation Myocardial Infarction
- Trial name
- BEEFBURGER (NCT04788186)
- Testing
- De-prescribe beta blocker therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Saskatchewan
Orthopedic Disorder, Post Operative Pain
TENS for Relief of Postoperative Pain in Orthopedic Patients
To ensure early mobilization, minimize suffering, and to prevent postoperative complications postoperative pain should be reduced as soon and as effectively as possible.
- Conditions
- Orthopedic Disorder, Post Operative Pain, Hip Fractures, Arthroplasty, Replacement, Hip
- Trial name
- NCT05678101
- Testing
- transcutaneous electrical nerve stimulation (TENS)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska University Hospital
Chronic Pain, Widespread
A Multi-disciplinary Pain Intervention (MUD-PI) for Patients With Chronic Widespread Primary Pain
Patients who fulfilled inclusion criteria and consented to participate received either treatment as usual at the clinic, or were enrolled in a group-therapy based intervention, the multi-disciplinary pain intervention, led by a…
- Trial name
- MUD-PI (NCT03413501)
- Testing
- MUD-PI
- Volunteers
- 49 people
- Sponsor
- Oslo University Hospital
Autism Spectrum Disorder (ASD), Anxiety
Adapted Group Therapy Compared With Usual Care for Anxiety and Depression in Adults With an Autism Diagnosis
The goal of this clinical trial is to learn whether an adapted group therapy works to treat anxiety and depression in adults with an autism diagnosis. The therapy is a form of cognitive behavioral therapy (CBT).
- Conditions
- Autism Spectrum Disorder (ASD), Anxiety, Depression
- Trial name
- CoMind (NCT07880028)
- Testing
- Autism-adapted group cognitive behavioral therapy
- Volunteers
- 154 people
- Sponsor
- Lovisenberg Diakonale Hospital
Severe Mental Disorder, Schizophrenia
Community-based Mental Health Care for People With Severe and Enduring Mental Ill Health (RECOVER-E) Croatia
To contribute to improving the level of functioning and quality of life and mental health outcomes for people with severe and enduring mental ill health (SMI) (schizophrenia, bipolar disorder, depression) by adapting and up…
- Conditions
- Severe Mental Disorder, Schizophrenia, Bipolar Disorder, Severe Depression
- Trial name
- RECOVER-E (NCT03862209)
- Testing
- Community mental health team
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Depression
A Community-based Resilience Group Psychotherapy for Only-child Loss Parents in China
Two communities in Changsha was selected, where principle investigators' institution located, to recruit 80 participants into intervention group and control group.
- Trial name
- NCT05410119
- Testing
- 8-week Resilience Group Psychotherapy, Usual care
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Central South University
Mental Disorder, Recovery, Psychological
Peer-based Recovery Program
Recovery-oriented services are currently the mainstream in the field of mental health around the world. Peer services are an alternative service option promoted by recovery advocates.
- Trial name
- NCT07262411
- Testing
- The Grow to Recovery program-Short Version
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- National Cheng-Kung University Hospital
Diabetes, Depression
INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study
To provide better care and preventive services for people with both depression and diabetes, the investigators propose to develop and test whether interventions to reduce depressive symptoms can be integrated into routine…
- Conditions
- Diabetes, Depression, Cardiovascular Risk Factor
- Trial name
- INDEPENDENT (NCT02022111)
- Testing
- Patient Education and Behavioral Activation, Supporting Self-Care (care coordinators), Psychiatrist and Diabetologist Reviews
- Where
- 4 sites in India
- Volunteers
- 404 people
- Sponsor
- Emory University
Lower Resp Tract Infection
An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care
The study is randomized clustered pragmatic trial whose objective is to decrease unnecessary antibiotic prescription in adult patients with lower respiratory tract infection managed at primary care level in Switzerland, using a…
- Trial name
- UltraPro (NCT03191071)
- Testing
- UltraPro, Procalcitonin, Blood sampling
- Where
- Switzerland
- Volunteers
- 469 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Profound Autism
Empowering Caregivers to Promote Child Independence
The proposed study aims to address the unique needs of caregivers and their adolescent children with profound autism. The constant supervision and 24/7 care that caregivers need to provide their children to ensure their health…
- Trial name
- NCT07059364
- Testing
- CAST Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Nebraska
Clinical Trial
Raising Healthy Children: A Hybrid Trial of the Family Check-Up 4 Health in Primary Care
This study is a hybrid implementation-effectiveness trial of the Family Check-Up 4 Health (FCU4Health), an adapted version of the Family Check-Up, in pediatric primary care.
- Trial name
- FCU4Health (NCT03013309)
- Testing
- Family Check-Up 4 Health, Treatment as usual
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- Arizona State University
Seizure Disorder, Seizure Disorder, Post Traumatic
Neuroimaging Biomarker for Seizures
This multi-site study will examine patients with epilepsy (ES) following head injury [i.e., posttraumatic epilepsy (PTE)] and posttraumatic psychogenic Non-epileptic seizures (PNES) and will compare them to patients with…
- Conditions
- Seizure Disorder, Seizure Disorder, Post Traumatic, Traumatic Brain Injury, Non-Epileptic Seizure
- Trial name
- NIBMSZS (NCT03441867)
- Testing
- Cognitive Behavioral Therapy for Seizures, Standard Medical Care
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Providence VA Medical Center
Opioid-use Disorder
Pilot Study of reSET-O to Treatment-as-usual in Acute Care Settings
This randomized controlled pilot study will evaluate feasibility, acceptability, and potential efficacy of an app, reSET-O, for patients being started on buprenorphine in acute care settings.
- Trial name
- NCT04817267
- Testing
- reSET-O app
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Patellofemoral Pain Syndrome
A Confirmatory Trial of Multidisciplinary Digital Therapeutics for Patellofemoral Pain Syndrome
This randomized controlled confirmatory study will be evaluating an mobile application, MORA Cure (ETH-01K), owned by EverEx, Inc., to examine safety and effectiveness in individuals with patellofemoral pain syndrome.
- Trial name
- NCT06260865
- Testing
- MORA Cure, Treatment as Usual
- Where
- 10 sites in South Korea
- Volunteers
- 216 people
- Sponsor
- EverEx Inc.
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