Clinical trials: Treatment as usual
Prematurity
Effectiveness Of Osteopathic Manipulative Treatment In NICU: A Multicenter Clinical Trial
The use of complementary and alternative medicine in neonatal ward has been steadily rising during the last decade. This integrated medicine approach has been shown to be helpful to improve neonatal health care.
- Trial name
- NCT01645137
- Testing
- osteopathic manipulative treatment, Usual care
- Where
- 3 sites in Italy
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Musculoskeletal Injury, Pediatrics
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
The TOP-MAP pilot trial has multiple goals. The first goal of this pilot clinical trial is to find out if it will be possible to carry out a study at multiple pediatric emergency department sites (Peds ED) comparing Non-Steroidal…
- Conditions
- Musculoskeletal Injury, Pediatrics, Sprain and Strain of Ankle, Sprain Knee
- Trial name
- TOP-MAP (NCT07145645)
- Testing
- Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Dental Caries, Gingivitis
Domiciliary Professional Oral Care for Dependent Elderly
Today's increase of dentate elderly, many of them dependent, is a challenge, both according to the personal daily oral hygiene and dentistry.
- Trial name
- NCT02669979
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Chronic Heart Failure, Iron Deficiency
Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN
This study will address whether the additional use of Intravenous (IV) iron on top of standard care will improve the outlook for patients with heart failure and iron deficiency.
- Conditions
- Chronic Heart Failure, Iron Deficiency, Left Ventricular Systolic Dysfunction
- Trial name
- IRONMAN (NCT02642562)
- Testing
- Ferric Derisomaltose
- Where
- 72 sites in United Kingdom
- Volunteers
- 1,160 people
- Sponsor
- University of Glasgow
Sarcoma
Radiographic Evaluation of Tumor Biology During Neoadjuvant Radiotherapy for Sarcoma
This is a single arm study in which patients will undergo MRI studies at 3 non-SOC timepoints (end of weeks 1, 3, and 5) while receiving SOC RT for their soft tissue sarcoma.
- Trial name
- NCT07487870
- Testing
- MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Andrew Frankart
Depressive Symptoms, Emotional Depression
Parenting-STAIR Modular for Military Fathers and OCONUS Families
The goal of this clinical trial is to learn if a family-based treatment called Parenting-STAIR-Modular (PSTAIR-M) can help military parents recover from trauma, strengthen emotion regulation skills, and improve parent-child…
- Conditions
- Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship
- Trial name
- NCT07843654
- Testing
- Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
- Where
- 6 sites in United States, South Korea
- Volunteers
- 243 people
- Sponsor
- New York University
Anxiety, Anxiety Disorders
Transdiagnostic, Cognitive and Behavioral Intervention for in School-aged Children With Emotional and Behavioral Disturbances
Background Impairing emotional and behavioural problems are common in children and adolescents and mark a three-fold increased risk of mental disorder in young adulthood.
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorders
- Trial name
- MindMyMind RCT (NCT03535805)
- Testing
- Mind My Mind (MMM), Treatment as Usual (TAU)
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Hypertension
Remote Monitoring and Social Support for Hypertension Management
A 3-arm randomized pilot trial aimed at comparing the effectiveness of different remote approaches to improving blood pressure (BP) control.
- Trial name
- SupportBP (NCT03416283)
- Testing
- Remote Monitoring, Remote Monitoring + Social Support
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Pennsylvania
Crohn's Disease in Remission
A Pilot Study Examining Low Sulfur Diet as Treatment for Persistent Symptoms in Quiescent Crohn's Disease
The goal of this study is to learn about a low sulfur diet in patients with Crohn's disease. Study participants will be randomized to receive a low sulfur diet or usual diet for 8 weeks.
- Trial name
- NCT05849012
- Testing
- Low Sulfur Diet, Usual Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Childhood Anxiety, Childhood Depression
Anxiety Among Children: Adaptation and Effectiveness of the Program Super Skills for Life in School Settings
Super Skills for Life (SSL) is a transdiagnostic prevention program designed for children with anxiety and depressive symptoms based on cognitive-behavioral therapy.
- Conditions
- Childhood Anxiety, Childhood Depression, Low Self-Esteem, Quality of Life (QOL)
- Trial name
- NCT07162402
- Testing
- Super Skills for Life (SSL) Program, No Active Intervention
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Fatima Jinnah Women University
Other Mental Conditions
Specialized Healthcare Service for BPD Patients: Athens Trial
A quasi-experimental pragmatic trial was developed to evaluate a specific health-care service for the treatment of biporal personality disorder (BPD) patients.The effectiveness and economic evaluation (cost-effectiveness and…
- Trial name
- BPDAS (NCT06392139)
- Testing
- Specific Therapy Program for Personality Disorders, Treatment As Usual (TAU) Group
- Where
- 3 sites in Greece
- Volunteers
- 156 people
- Sponsor
- Ioannis A. Malogiannis
Cancer
Patient Outcomes of a Self-care Management Approach to Cancer Symptoms: A Clinical Trial
Regardless of their treatment, cancer patients endure a variety of difficult symptoms during their disease with averages ranging from 7 to 14 symptoms each.
- Trial name
- NCT02288169
- Testing
- COPE, Support/Attention Control
- Where
- United States
- Volunteers
- 515 people
- Sponsor
- University of South Florida
Breast Cancer, Lung Cancer
Accountability for Cancer Care Through Undoing Racism and Equity
Purpose: African American cancer patients, as compared to their White counterparts, continue to initiate treatment later and remain less apt to undergo complete treatment; fueling worse treatment outcomes including shorter…
- Trial name
- ACCURE (NCT01954641)
- Testing
- ACCURE Navigator, Usual Care by Cancer Center Care Team
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of North Carolina, Chapel Hill
Subjective Cognitive Decline, Alzheimer Dementia
Davos Alzheimer's Collaborative Healthcare System Preparedness to Increase Cognitive Assessment Rates for Older Adults
In this study the investigators explore a pragmatic strategy to increase cognitive screening rates in the community. The investigators will compare the monetary value of different combinations of SCD questionnaires, digital…
- Trial name
- NCT06191952
- Testing
- Cognigram, Subjective cognitive decline questionnaire (SCD-Q), blood-based biomarkers
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Schizophrenia
Cognitive Remediation Program for Hospitalized in the Long Term Patients With Deficit Schizophrenia
Schizophrenia is a chronic disease with deficit in social interaction and lost of autonomy in daily life. Negative symptoms as blunted affect, avolition, social deficit and anhedonia and cognition were prognosis and functioning…
- Trial name
- IPT+ (NCT03407950)
- Testing
- IPT+, Treatment as usual
- Where
- France
- Sponsor
- University Hospital, Montpellier
Mental Disorders, Domestic Violence
NET in Iranian Women Suffering From Post Traumatic Stress Symptoms
The proposed study seeks to investigate to what extent Narrative Exposure Therapy (NET) is an effective treatment for the reduction of symptoms of Post-Traumatic Stress Disorder (PTSD) and depression and for the improvement of…
- Trial name
- NCT01731418
- Testing
- Narrative Exposure Therapy, Treatment-as-usual
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Stress-related Illness/Anxiety
Medical Yoga for Patients With Stress-related Symptoms
The purpose of this study is to compare the effect of Medical Yoga as a group treatment, to conventional treatment provided by a physical therapist, for people with perceived stress-related symptoms.
- Trial name
- NCT02907138
- Testing
- Medical Yoga, Treatment as Usual (physical therapy)
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Maria Larsson
Emotional Dysfunction, Psychosis
Application of UP for Transdiagnostic Treatment of Emotional Disorders for UHR for Psychosis Patients
The principal aim of the study is to assess the efficacy of the Unified Protocol (UP) for the treatment of the comorbid symptomatology of patients with Ultra High Risk (UHR) for psychosis.
- Trial name
- NCT04929938
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Fundació Sant Joan de Déu
Cognitive/Functional Effects, Malignant Neoplasm
Collaborative Targeted Case Management in Improving Functional Status in Patients With Stage III-IV Cancer
This randomized clinical trial studies collaborative targeted case management in improving functional status in patients with stage III-IV cancer.
- Conditions
- Cognitive/Functional Effects, Malignant Neoplasm, Pain
- Trial name
- NCT01721343
- Testing
- telephone-based intervention, case management, management of therapy complications
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- Mayo Clinic
Postpartum Depression, Postpartum Anxiety
Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression
To conduct a randomized controlled trial (N=408) examining the impact of an online cognitive behavioural therapy (CBT)-based workshop on rates of postpartum depression (i.e., EPDS scores at 2-months postpartum) when added to…
- Trial name
- NCT05753176
- Testing
- Online 1-Day Cognitive Behavioural Therapy-Based Workshop
- Where
- Canada
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- McMaster University
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