Clinical trials: Treatment as usual
Sars-CoV2
Evaluation of the Pharmacokinetics and Pharmacodynamics of Hydroxychloroquine in COVID-19 Intensive Care Unit Patients
To date, no treatment has demonstrated clinical efficacy on COVID 19. However, several therapeutic strategies are being considered and are being evaluated in numerous clinical trials.
- Trial name
- PREAVIS (NCT04522466)
- Testing
- Hydroxychloroquine (HCQ)
- Where
- 4 sites in France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Schizophrenia; Psychosis
Music Therapy for People With Schizophrenia and Relates Psychosis.
Treatment of symptoms, rehabilitation of cognitive deficits, improvement of social functioning and quality of life in schizophrenia and other psychoses are approached through a comprehensive strategy that combines…
- Trial name
- NCT04777266
- Testing
- Music therapy and treatment as usual
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- State reference center for psychosocial care
Schizophrenia
Art Therapy in Acute Schizophrenia
Randomised, controlled, single-blinded pilot study to assess the efficacy of psychodynamic art therapy in a sample of hospitalized, (sub)acutely psychotic patients with a diagnosis of schizophrenia compared to a group of patients…
- Trial name
- KUSS (NCT01622166)
- Testing
- psychodynamic art therapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Endometriosis
MY-ENDO -- Mind Your ENDOmetriosis: a Digital Mindfulness- and Acceptance-based Endometriosis Self-management Program
The purpose of the study is to assess the effect of a digital mindfulness- and acceptance-based psychological intervention on quality of life, work ability, pain experience and physical and mental health in participants…
- Trial name
- NCT06211231
- Testing
- Digitally delivered mindfulness- and acceptance-based psychological intervention
- Where
- 2 sites in Denmark
- Volunteers
- 255 people
- Sponsor
- University of Aarhus
Bipolar Depression
A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression
The purpose of this study is to o evaluate the antidepressant efficacy of the PEA in Bipolar Depression and the association between antidepressant response with endogenous cannabinoids and cytokine levels
- Trial name
- NCT06229977
- Testing
- Palmitoylethanolamide (PEA), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Rodrigo Machado-Vieira, MD, PhD, MSc
Knee Pain Chronic, Knee Osteoarthritis
Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace
The goal of this intervention study is to assess the effect of blood flow restricted (BFR) exercise integrated into the daily work tasks among hospital workers with or at increased risk of chronic knee pain.
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Knee Discomfort
- Trial name
- NCT05822401
- Testing
- Blood flow restriction (BFR), Usual care (control)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Obstructive Sleep Apnea
Impact of Automated Education and Follow-up Mechanisms on Patient Engagement
The primary and well-known challenge with continuous positive airway pressure (CPAP) is the incomplete adherence of patients to this therapy.
- Trial name
- EmmiUSleep (NCT02279901)
- Testing
- Telemedicine Education, IVR
- Where
- United States
- Volunteers
- 1,873 people
- Sponsor
- Kaiser Permanente
Communication Research
Using a Nurse-Led Communication Strategy for Surrogates in the Intensive Care Unit
Communication is one of the greatest health needs for high quality end-of-life (EOL) care in the intensive care unit (ICU), especially when patients are too ill to speak for themselves and rely on surrogates to make EOL…
- Trial name
- NCT03770481
- Testing
- nurse-led communication strategy
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Lipid Disorder, Hypercholesterolemia
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders (EMERALD) is a protocolized intervention based on American College of Cardiology/American Heart Association and US Preventive Services Task Force guidelines…
- Conditions
- Lipid Disorder, Hypercholesterolemia, Cardiovascular Diseases, Atherosclerosis
- Trial name
- EMERALD RCT (NCT06488105)
- Testing
- Statin (rosuvastatin 10 or 40 mg daily, depending on risk), Healthy Lifestyle Counseling, Outpatient Followup
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Wake Forest University Health Sciences
Stress Disorders, Post-Traumatic
Examine the Preliminary Effect of an Evidence-Based Practice (EBP) Consultation Model on Staff Fidelity to EBP
Youth involved in the juvenile justice system report high rates of exposure to traumatic events (>90%) and posttraumatic stress disorder (PTSD; 20-50%).
- Trial name
- NCT03722745
- Testing
- TARGET, TAU
- Sponsor
- NYU Langone Health
Severe Acute Malnutrition, Moderate Acute Malnutrition
Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Democratic Republic of Congo
Acute malnutrition affects 51 million children under the age of 5 worldwide. Malnutrition contributes to nearly half of all child deaths each year, with the forms characterized by wasting or oedema (acute malnutrition) associated…
- Conditions
- Severe Acute Malnutrition, Moderate Acute Malnutrition, Child Malnutrition, Acute Malnutrition
- Trial name
- OptiMA-DRC (NCT03751475)
- Testing
- Nutritional Strategy - OptiMA, Effective nutritional standard strategy
- Where
- Democratic Republic of the Congo
- Volunteers
- 896 people
- Sponsor
- Alliance for International Medical Action
Congestive Heart Failure (CHF), Systolic Dysfunction
Improving Heart Failure Care in Minority Communities
For congestive heart failure (CHF) patients with systolic dysfunction, a randomized controlled trial compared nurse-based disease management to address problems in patient and clinician management with usual care for effects on…
- Trial name
- NCT00211874
- Testing
- Nurse-management
- Where
- 4 sites in United States
- Volunteers
- 406 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteoarthritis, Knee
Effects of Semi-standarized Acupuncture in Chronical Symptomatic Osteoarthritis of the Knee Through: A Randomized Controlled Trial
Introduction: Knee osteoarthritis is a long-term rheumatic disease with a significant impact on the patient's quality of life and the socio-economic development of societies.
- Trial name
- NCT05096806
- Testing
- Acupuncture, TENS
- Volunteers
- 56 people
- Sponsor
- Universitat de Girona
Global Developmental Delay
Virtual Reality and Neuropsychiatric Rehabilitation in Patients With Global Developmental Delay.
Global Developmental Delay is a disorder characterized by failure achievement of expected milestones in different areas of psychomotor development before 5 years of age.
- Trial name
- NCT05879952
- Testing
- TAU + BTsN session, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Cognitive Decline, Cancer
Combined Model of Online Remote Interventions for Cancer-Related Cognitive Impairment
Cancer survival rates have increased dramatically in recent years. However, many survivors report cognitive decline following treatment, which significantly impairs their quality of life.
- Trial name
- CRCI (NCT04210778)
- Testing
- Cognitive orientation to daily occupational performance (CO-OP), Computerized Cognitive Training (BrainHQ, posit science)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Spasticity, Muscle
Effect of Transcutaneous Auricular Nerve Stimulation vs Body Rocking Exercises on Spasticity of Upper Limb
The primary aim of this study is to compare the effect of TANS and body rocking exercises on reducing upper limb spasticity in young stroke patients( under 50).
- Trial name
- NCT06914115
- Testing
- TANS Group, Body Rocking Exercise
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Superior University
Brain Concussion
Sleep After Adolescent Concussion
The purpose of this research study is to learn more about how sleep changes as teens recover from concussions. We also want to learn if we can improve sleep in teens who have concussions.
- Trial name
- NCT03781076
- Testing
- Sleep Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Hemophilia
Fascial Therapy in Elbow Hemophilic Arthropathy
Introduction: The common clinical manifestations of hemophilia are skeletal muscle bleeds, especially hematomas and hemarthrosis. Repeated episodes of joint bleeding in certain joints, causing a progressive joint deterioration.
- Trial name
- HeL-Fascial (NCT03009591)
- Testing
- Experimental group
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Real Fundación Victoria Eugenia
Depressive Disorder
Depression Attention for Women Now (The DAWN Study)
Major depressive disorder (MDD) is a common disabling illness that disproportionately affects women, with prevalence rates two times those of men.
- Trial name
- DAWN (NCT01096316)
- Testing
- Depression Care Management
- Where
- 2 sites in United States
- Volunteers
- 205 people
- Sponsor
- University of Washington
Osteoarthritis, Knee
Physiotherapy and Therapeutic Education After Total Knee Arthroplasty.
The purpose of this study is to test whether adding a treatment using pain neuroscience education (PNE) and coping skills training (CST) to usual care, in subjects with knee osteoarthritis and pain catastrophizing, who are…
- Trial name
- NCT03198247
- Testing
- Usual care, PNE + CST
- Where
- Spain
- Sponsor
- Centro Universitario La Salle
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