Clinical trials: Treatment as usual
Atelectasis, Pulmonary Complications
Evaluation of The MetaNeb® System to Reduce Postoperative Pulmonary Complications
To determine if a therapy regimen including treatment with The MetaNeb® System had a positive impact on the rate of pulmonary complications related to atelectasis and/or secretion retention that occur in high risk post-operative…
- Trial name
- NCT02627742
- Testing
- MetaNeb® System
- Where
- 3 sites in United States
- Volunteers
- 419 people
- Sponsor
- Hill-Rom
Alcohol Use Disorder (AUD), Attentional Bias
Attentional Control Training for Treating Alcohol Use Disorder
Background: There is consistent evidence that community and clinical samples of individuals with an alcohol use disorder (AUD) have attentional biases toward alcohol cues.
- Trial name
- NCT05102942
- Testing
- Attentional Control Training Program
- Where
- Denmark
- Volunteers
- 268 people
- Sponsor
- University of Southern Denmark
Irritability, Anger
CBT for Anger and Aggression in Children: a Pilot Study of Irritability and Suicidality
This pilot study evaluated whether cognitive behavioral therapy for anger and aggression, added to treatment as usual, was associated with reductions in irritability and suicidal ideation in preteen children with externalizing…
- Conditions
- Irritability, Anger, Externalizing Behavior, Suicidal Ideation
- Trial name
- NCT07603986
- Testing
- Cognitive Behavioral Therapy for Anger and Aggression, Treatment as Usual (TAU)
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Geha Mental Health Center
Asthma Chronic, Adherence, Medication
Pictograms to Facilitate Comprehension of Medical Indications
SIMAP is a triple-masked randomised trial aimed at assessing whether an automated system of pictograms associated to medical indications results in better comprehension and adherence of said indications.
- Conditions
- Asthma Chronic, Adherence, Medication, Primary Health Care
- Trial name
- SIMAP (NCT05609760)
- Testing
- SIMAP, Usual Care
- Where
- 4 sites in Chile
- Volunteers
- 22 people
- Sponsor
- Universidad de Concepcion
Smoking Cessation, Diabetes Type 2
Diabetes and Smoking Cessation: a Gender-Oriented Study
People with diabetes still smoke at equivalent rates as non-diabetics. There is lack of evidence regarding interventions for smoking cessation among individuals with diabetes.
- Trial name
- DiSCGO (NCT03426423)
- Testing
- Behavioral smoking cessation intervention, Control
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Carole Clair
Cancer
An Intervention to Promote Oral Agent Adherence and Symptom Management: ADHERE
This study includes a novel intervention entitled "ADHERE," which includes one semi-structured 30-minute face-to-face session and three 10-minute weekly phone sessions over 4 weeks, administered by an advanced practice nurse…
- Trial name
- NCT02337296
- Testing
- ADHERE
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Michigan State University
Substance Use Disorder (SUD), Drug Abuse
Adapted RPM-08 for Substance Use Disorder in Pakistan
The goal of this clinical trial is to learn if a culturally adapted Relapse Prevention Module (RPM-08) can reduce relapse risk in people with substance use disorders in Pakistan.
- Conditions
- Substance Use Disorder (SUD), Drug Abuse, Relapse
- Trial name
- NCT07552623
- Testing
- Adapted Relapse Prevention Module (RPM-08), Treatment as Usual (TAU)
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Universiti Sains Malaysia
Heart Failure
Palliative Care for Heart Failure Patients
The purpose of this study is to assess the impact of palliative care consultation on quality of life and symptom management for patients hospitalized with acute heart failure with a randomized control trial at Abbott Northwestern…
- Trial name
- NCT01519479
- Testing
- Palliative Care Consultation, Control
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Allina Health System
Suicide, Depressive Disorder, Major
Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide
This research study is designed to answer specific questions about new ways to provide services for youth at-risk of suicide.
- Conditions
- Suicide, Depressive Disorder, Major, Anxiety Disorders, Suicidal Ideation
- Trial name
- PASS (NCT03016572)
- Testing
- Standard of Care, Crisis Intervention, Wraparound Services
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Cleveland Clinic
Posttraumatic Stress Disorder
CBITS - Treat Trauma in Child Welfare
The goal of this randomized controlled trial is to evaluate the effectiveness of the trauma-focused group intervention CBITS compared with enhanced treatment as usual (TAU+) in child welfare programs in Germany.
- Trial name
- CBITS (NCT06038357)
- Testing
- CBITS, TAU+
- Volunteers
- 90 people
- Sponsor
- University Hospital Ulm
Cognitive Impairments, Stroke
Digital Support for People With Cognitive Impairment
Cognitive impairment may cause problems in planning and initiating daily activities, as well as remembering to do what is scheduled.
- Conditions
- Cognitive Impairments, Stroke, Brain Injuries
- Trial name
- NCT04470219
- Testing
- Cognitive support by RemindMe
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Linkoeping University
Feeding and Eating Disorders, Anorexia Nervosa
Cognitive Training for Patients With Eating Disorders
Eating disorders are severe mental illnesses, mainly affecting adolescent- and young adult women. The prognoses for eating disorders are relatively poor, and a large part of patients with these illnesses do not benefit from…
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- TCRTRCT (NCT03808467)
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF)
Clinical Trials for Elderly Patients With Multiple Disease
The CHROMED project focuses its investigation on the applicability of an integrated solution for a pathological condition which: a) is very prevalent in ageing patients and b) severely impairs quality of life: COPD with other…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF), Sleep Disordered Breathing (SDB)
- Trial name
- CHROMED (NCT01960907)
- Testing
- CHROMED monitoring system
- Where
- 6 sites in Estonia, Slovenia and 3 more
- Volunteers
- 312 people
- Sponsor
- Restech Srl
Depression
Pharmacogenetic-Directed Treatment for Major Depression
Determine if antidepressant treatment guided by pharmacogenetic algorithm and interpretive report improves outcomes when compared with standard treatment without the availability of genetic information.
- Trial name
- NCT01261364
- Testing
- GeneSightRx, Treatment as usual
- Volunteers
- 50 people
- Sponsor
- Assurex Health Inc.
Schizophrenia, Treatment Resistant Schizophrenia
Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial
Schizophrenia is one of the most severe and costliest mental disorders in terms of human suffering and societal expenditure. About 15-30% of patients do not respond to all known antipsychotics, including clozapine, the current…
- Trial name
- MECT-RESIST (NCT06456983)
- Testing
- maintenance electroconvulsive therapy (mECT)
- Where
- 14 sites in Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Critical Illness, Communication
Time Limited Trials to Reduce Non-Beneficial Intensive Care Unit Treatments
Overutilization of intensive care unit (ICU) treatments among patients with advanced medical illnesses and poor prognosis places them at risk for prolonged suffering with minimal anticipated benefit.
- Trial name
- NCT04181294
- Testing
- Family meetings using time limited trials as default ICU communication and care planning approach, Usual practice
- Where
- 3 sites in United States
- Volunteers
- 209 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Severe Depressive Symptoms
Effectiveness of Internet-based Depression Treatment (EVIDENT) in Severe Depression
Online self-help is an innovative way of providing self-help. The investigators want to study the effect of an interactive online self-help-program (Deprexis) in the treatment of severe depressive symptoms.
- Trial name
- NCT02178631
- Testing
- Deprexis, CAU
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of Luebeck
Depressive Episode
Role Of Non-Specific Effects in The Treatment of Depression With Esketamine
The investigators aim to examine the magnitude of non-specific effects in the treatment of depressive episodes with esketamine, by providing patients in the intervention group with a pretreatment presentation and post-treatment…
- Trial name
- ROSETTE (NCT05910775)
- Testing
- Pre and Post Treatment Presentations
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Yale University
Multiple Sclerosis, Relapsing-remitting
Evaluation of a Modified Paleolithic Dietary Intervention in the Treatment of Relapsing-Remitting Multiple Sclerosis
This is a research study. The investigators are inviting participants to participate in this research study between the ages of 18-45, who have stable Relapsing-Remitting Multiple Sclerosis (RRMS), are able to walk 25 ft…
- Trial name
- NCT02687919
- Testing
- Modified Paleo diet
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Amanda Irish
Heart Failure
Exploring Behavioral Interventions to Improve Heart Failure
The objective of this research is to compare Tai Chi versus Resistance Exercise, Health Education and usual care for changes in cardiac functional capacity measured for ability of the heart to pump by measuring ejection fraction…
- Trial name
- NCT01625819
- Testing
- Tai Chi, Resistance Band, Health Education
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of California, San Diego
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