Clinical trials: Treatment as usual
COPD
The Clinical Characteristics, Treatment and Prognosis of Tuberculosis-associated COPD
Chronic obstructive pulmonary disease (COPD) still imposes a substantial health and economic burden worldwide. Pulmonary tuberculosis has been confirmed as an important risk factor for COPD and this specific phenotype is thereby…
- Trial name
- NCT06074042
- Testing
- previous pulmonary tuberculosis
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Peking University Third Hospital
Osteoarthritis, Knee, Osteoarthritis, Hip
BMAC in Severe Hip or Knee Osteoarthritis Awaiting Arthroplasty
The prevalence of severe and disabling osteoarthritis of the hip and/or knee in Albertans is high and increasing. Existing nonsurgical treatments often inadequately control symptoms.
- Trial name
- NCT03908827
- Testing
- Bone Mineral Aspirate Concentrate (BMAC)
- Where
- Canada
- Sponsor
- CAPRI Clinic
Chronic Pain, Musculoskeletal Pain
The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System
The goal of this study is to improve pain care in the MHS by identifying effective, whole-person, non-pharmacologic interventions for persons with chronic musculoskeletal pain.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Musculoskeletal Pain Disorder
- Trial name
- PROs (NCT06940986)
- Testing
- Empowered Relief, Move to Health, Usual Care as determined by primary care provider
- Where
- 5 sites in United States
- Volunteers
- 608 people
- Sponsor
- Brooke Army Medical Center
Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation
Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke
The goal of this observational study is to learn about the role of MRI evaluation based on FVH-DWI mismatch principle in preoperative evaluation of endovascular thrombolectomy.
- Conditions
- Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation, Endovascular Thrombectomy
- Trial name
- NCT06213870
- Testing
- Surgical criteria
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Tianjin Huanhu Hospital
Insomnia, TBI (Traumatic Brain Injury)
Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury
The objective of the study is to conduct a randomized controlled trial of Cognitive Behavioral Therapy for Insomnia (CBT-I) in a sample of active-duty sailors with a history of traumatic brain injury (TBI).
- Trial name
- CBTBI (NCT06867666)
- Testing
- In Person CBT-I, CBT-I via COAST
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Noctem, LLC
Depressive Disorder, Major
Predictors of Treatment Response in Late-onset Major Depressive Disorder
Depression is a common disorder, especially in old age, where it is associated with significant morbidity and mortality. This study will investigate whether there are features of individual patients with major depression that may…
- Trial name
- NCT02546024
- Testing
- Standard care
- Volunteers
- 40 people
- Sponsor
- King's College London
Schizophrenia, Psychosis
Minnesota Community-Based Cognitive Training in Early Psychosis
The purpose of this study is to determine whether cognitive training exercises can improve cognitive functioning in young patients with recent-onset psychosis who are being treated in community mental health settings using the…
- Conditions
- Schizophrenia, Psychosis, Schizoaffective Disorder, Schizophreniform Disorders
- Trial name
- Mini-COTES (NCT03079024)
- Testing
- Targeted Cognitive Training, General Cognitive Exercises, Coordinated Specialty Care for First Episode Psychosis
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Minnesota
Depression
Culturally Sensitive Depression Care Management for Latino Primary Care Patients
The purpose of this study is to determine whether telephonic depression care management can improve depression outcomes for Latino primary care patients who are enrolled in Medicaid and are receiving an antidepressant from their…
- Trial name
- NCT00571454
- Testing
- telephone depression care management
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Butler Hospital
Depression Chronic, Depression and Quality of Life
Remote Medical Monitoring of Patients With Depression
The goal of this clinical trial is to learn if ThIA Suivi, a digital tool for remote monitoring of patients, can improve the care of adults with depression who are followed by a psychiatrist.
- Conditions
- Depression Chronic, Depression and Quality of Life, Depression, Major Depressive Episode
- Trial name
- TELEMED-DEP (NCT07878754)
- Testing
- Use of ThIA Medical Device
- Where
- 3 sites in France
- Volunteers
- 608 people
- Sponsor
- ThIA Santé Mentale
Autism Spectrum Disorder, Autism
A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism
The purpose of this study is to examine the effectiveness of pivotal response training (PRT) in an intensive center-based environment to treat social communication deficits in children with autism spectrum disorder (ASD).
- Trial name
- PRT-C (NCT03778827)
- Testing
- Intensive Center-Based Pivotal Response Treatment (PRT-C)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Sudden Cardiac Death
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)
The PROTECT-ICD trial is a physician-led, multi-centre randomised controlled trial targeting prevention of sudden cardiac death in patients who have poor cardiac function following a myocardial infarct (MI).
- Trial name
- PROTECT-ICD (NCT03588286)
- Testing
- Electrophysiology study (EPS), Standard Care, Cardiac Magnetic Resonance (CMR)
- Where
- 52 sites in United States, Australia and 13 more
- Volunteers
- 1,058 people
- Sponsor
- Western Sydney Local Health District
Heart Failure
Motivational Interviewing Tailored Intervention for Patients With Heart Failure (MITI-HF)
This study will test the effectiveness of motivational interviewing and skill building compared to usual care to improve self-care in heart failure (HF) patients.
- Trial name
- MITI-HF (NCT02177656)
- Testing
- Motivational Interviewing tailored intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ruth Masterson-Creber
Randomized Controlled Trial
Efficacy of ACT in Patients Scheduled for Lumbar Spine Surgery
Objectives: (1) To analyze the effectiveness of adding a group-based form of Acceptance and Commitment Therapy (ACT) to the treatment as usual (TAU) for preoperative patients diagnosed with degenerative lumbar pathology plus…
- Trial name
- SPINE-ACT (NCT05634122)
- Testing
- Acceptance and Commitment Therapy (ACT), Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Parc de Salut Mar
Depressive Symptoms Mild to Moderate in Severity, Major Depressive Disorder
Adolescent Interpersonal Counseling in Primary Care
The demand for prevention and treatment of adolescent depression has rapidly increased over years. A national project to improve treatment of adolescent depression in primary care has taken place in Finland starting 2020.
- Trial name
- NCT06390462
- Testing
- Interpersonal counseling, Treatment as usual, No support, intervention or other treatment
- Where
- 4 sites in Finland
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Schizophrenia, Schizoaffective Disorder
A Study to Assess the Clinical Utility of Antipsychotic Medication Levels in Plasma as Determined by Liquid Chromatography-Tandem Mass Spectrometry
The purpose of this study is to determine the number of Medication Treatment Modifications (MTMs) made by the clinician at every visit when antipsychotic medication plasma levels (AMPL) results are available compared to when AMPL…
- Trial name
- NCT02462473
- Testing
- Aripiprazole, Olanzapine, Paliperidone
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Janssen Research & Development, LLC
Postpartum Depression
Preventing Postpartum Depression in Immigrant Latinas
Postpartum depression (PPD) affects 10-20% of women, with immigrant Latinas disproportionately affected. PPD prevention and treatment is limited among immigrant Latinas due to an array of structural and cultural factors…
- Trial name
- NCT05873569
- Testing
- Mothers and Babies Virtual Group Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Type 2 Diabetes
Impact of Accu-Chek 360 in Veterans With Type 2 Diabetes
To show that a structured treatment plan based upon Accu-Chek 360 View has a favorable effect on physician decision-making and HbA1c for patients on oral hypoglycemic agents (OHA) or insulin for type 2 diabetes (T2D).
- Trial name
- NCT00824694
- Testing
- Targeted Self-Monitoring Of Blood Glucose (SMBG), Provider Training, Patient Education
- Where
- 3 sites in United States
- Volunteers
- 348 people
- Sponsor
- Biomedical Research Institute of New Mexico
Hypertension
Effect of Motivational Interview as a Strategy in the Reduction of Blood Pressure.
This randomized clinical trial was designed to test the effectiveness of Motivational Interviewing in lowering blood pressure during six months follow-up.
- Trial name
- NCT02892929
- Testing
- Motivational interviewing, Prescriptive Consultation
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Anxiety, Depression
Digital Single Session Intervention for Youth Mental Health
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist…
- Conditions
- Anxiety, Depression, Conduct Disorder, Stress
- Trial name
- NCT05449002
- Testing
- Practicing the Opposite (PTO), Usual Clinical Care
- Where
- 5 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Harvard University
Postpartum Depression, Anxiety
Mothers and Babies Qatar (MB-Q): A Postpartum Depression Intervention
Qatar Mothers and Babies is a 4-year collaboration between Northwestern University Feinberg School of Medicine and Sidra Medicine in Doha, Qatar that will generate and evaluate a cultural and contextual adaptation of the Mothers…
- Conditions
- Postpartum Depression, Anxiety, Diabetes
- Trial name
- MB (NCT04442529)
- Testing
- Mothers and Babies (MB)
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sidra Medicine
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