Clinical trials: Treatment as usual
Atopic Dermatitis, Inflammatory Skin Disease
Evaluation of Efficacy and Safety of Enhanced External Counter-pulsation on Patients With Atopic Dermatitis and Inflammatory Skin Disease Requiring Wet Wrap Therapy
Patients with atopic dermatitis (AD) and erythematous skin disease are often treated with topical treatment containing corticosteroids.
- Trial name
- NCT06448702
- Testing
- wet wrap therapy, External compression counter-pulsation (EECP)
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Asthma
Developing and Implementing Asthma-Guidance and Prediction System (a-GPS) for Better Asthma Management
Asthma is the most common chronic condition in children and one of the five most burdensome diseases in the United States. Despite this, research and care for childhood asthma are limited by inefficient utilization of electronic…
- Trial name
- NCT02865967
- Testing
- Usual care + a-GPS, Usual care
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
Effects of Reparel™ Knee Sleeve on Knee Osteoarthritis
The goals of treating knee osteoarthritis (OA) is to improve or maintain quality of life, mobility and function, pain relief, and improve inflammation.
- Trial name
- NCT04743921
- Testing
- Reparel Knee Sleeve
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Alabama at Birmingham
Substance Use, Substance Abuse
Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3
Developed from adapting and combining two evidence-based programs, Project CONNECT (a linkage-to-services program that targets barriers within the probation and substance abuse treatment systems) and TIES (a program that teaches…
- Conditions
- Substance Use, Substance Abuse, Substance Use Disorders, Substance-Related Disorders
- Trial name
- NCT03048552
- Testing
- Family CONNECT
- Volunteers
- 22 people
- Sponsor
- New York State Psychiatric Institute
Back Pain Lower Back Chronic
Tai Chi for Chronic Low Back Pain in Older Adults
There is a major gap in knowledge about safe and effective treatment options for older adults with chronic low back pain. This project will determine the feasibility of conducting a full-scale trial evaluating Tai Chi, a…
- Trial name
- NCT03299192
- Testing
- Tai Chi, Health Education, Usual Medical Care
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Kaiser Permanente
Neuromuscular Diseases
Methods to Improve Expiratory Cough Flow and Lung Volume in Children With NMDs
Children with neuromuscular diseases (NMDs) and weak chest muscles suffer frequent chest infections, hospital admissions and reduced life expectancy.
- Trial name
- NCT02342132
- Testing
- Non-invasive bipap ventilator, Mechanical insufflator-exsufflator, High frequency percussive oscillator
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Lung Cancer
Educational Intervention for Patients Undergoing Surgery for Lung Cancer
The goal of this interventional study is to learn about the effect of a structured educational intervention in patients undergoing surgery for lung cancer.
- Trial name
- LUNG-SURG-EDU (NCT07614204)
- Testing
- Structured Educational Intervention, Usual Care
- Where
- Greece
- Volunteers
- 160 people
- Sponsor
- National and Kapodistrian University of Athens
Critical Illness, Cardiac Complication
The INSIGHT Feasibility Study Ultrasound in the Intensive Care Unit: A Randomised Controlled Feasibility Trial
Point-of-care ultrasound (PoCUS) is a rapidly evolving method of clinical assessment within the intensive care unit (ICU) with training predominantly aimed at physicians.
- Conditions
- Critical Illness, Cardiac Complication, Pleural Effusion, Consolidation
- Trial name
- INSIGHT (NCT05569798)
- Testing
- Whole body point of care ultrasound scan
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- King's College Hospital NHS Trust
Depression Anxiety Disorder, Psychological Distress
Evaluating the Effectiveness of a School-based Stepped Care Treatment Model for Adolescent Depression in Pakistan
This study aims to test the effectiveness of a stepped-care model to reduce depressive symptoms in adolescents in school settings in Pakistan.
- Conditions
- Depression Anxiety Disorder, Psychological Distress, Well-Being, Psychological
- Trial name
- SMART-STEP (NCT07399314)
- Testing
- Universal Intervention & CBT-based Guided Self-Help Application
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- Global Institute of Human Development
Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization
This phase Ib/II trial studies the side effects and best dose of ibrutinib and how well it works in treating patients with COVID-19 requiring hospitalization.
- Conditions
- Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Monoclonal B-Cell Lymphocytosis
- Trial name
- NCT04439006
- Testing
- Best Practice, Ibrutinib
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jennifer Woyach
Depression
Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid)
Although evidence-based clinical interventions (CI) are a preferred treatment option for patients with depression, CIs are rarely available in community primary care settings.
- Trial name
- NCT06494384
- Testing
- Problem Solving Treatment as usual (PST as usual), Problem Solving Treatment Aid (PST-Aid)
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Washington
Extreme Prematurity
Stockholm Preterm Interaction-Based Intervention
Extreme premature Children will at discharge from Karolinska Hospital and Södersjukhuset in Stockholm be asked to participate in a study, examining the effects of a home-visit based post-discharge program aiming at facilitating…
- Trial name
- SPIBI (NCT03714633)
- Testing
- Stockholm Preterm Interaction-Based Intervention (SPIBI)
- Where
- 5 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Stockholm University
Major Depression, Treatment Resistant Depression
Combining rTMS and tDCS in Depression: an Exploratory Clinical Trial
The investigators aim to conduct a single-arm open-label clinical trial, meaning that the investigators will be administering a treatment protocol to one group of patients, where no information is withheld from trial…
- Trial name
- CombTMS (NCT06500533)
- Testing
- rTMS combined with tDCS
- Where
- Denmark
- Volunteers
- 7 people
- Sponsor
- Regionspsykiatrien Gødstrup
Emergency Department Visit, Home Care Services
Acute Hospital Care at Home for People Living With Dementia
The investigators will perform a parallel-group multicenter randomized controlled trial of a 1-year pre-enrolled acute hospital care at home intervention vs usual care for people living with dementia.
- Conditions
- Emergency Department Visit, Home Care Services, Dementia
- Trial name
- NCT06819852
- Testing
- Acute hospital care at home, Standard medical treatment
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Brigham and Women's Hospital
Patient Health Behaviors
Study of Screening Self-management Goals on Short Term Behavior Change
The purpose of this study is to test whether having patients identify a self-management goal (health goal), prior to a visit with their primary care provider, leads to health behavior improvement over six weeks.
- Trial name
- NCT01936311
- Testing
- Self-management goal elicitation
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Denver Health and Hospital Authority
Irritable Bowel Syndrome
Efficacy of Esketamine for Patients With Irritable Bowel Syndrome
To explore the efficacy of a single low dose of esketamine for patients with irritable bowel syndrome (IBS).
- Trial name
- NCT06788444
- Testing
- The colonoscopy, Esketamine
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Beijing Tiantan Hospital
Suicide, Suicide Attempt
Evaluation of a Telehealth Case Management Intervention to Prevent Suicide Among Soldiers Discharged From Psychiatric Hospitalization
This study evaluates the effectiveness of Pathfinding, a 6-month, remotely-delivered case management intervention designed to decrease suicidal behavior among active-duty Regular Army soldiers recently discharged from inpatient…
- Trial name
- NCT07404787
- Testing
- Pathfinding, Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Uniformed Services University of the Health Sciences
Telepsychotherapy, Attention Deficit Disorder With Hyperactivity (ADHD)
Effects of Telepsychiatric Parent Training on Caregivers of Children With ADHD (TPT-ADHD)
This study was conducted to examine the effects of a telepsychiatric parent training program implemented for primary caregivers of children with Attention Deficit Hyperactivity Disorder (ADHD).
- Conditions
- Telepsychotherapy, Attention Deficit Disorder With Hyperactivity (ADHD), Children, Caregiver
- Trial name
- TPT-ADHD (NCT06884007)
- Testing
- Telepsychiatric Parent Training Program, Routine Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Uşak University
Lung Transplant Infection, Hepatitis C
Lung Transplant HCV, Pilot Study
In this study HCV negative recipients will be transplanted with HCV positive lungs. Investigators will attempt to decrease infectivity rates by performing Normothermic Ex vivo Lung Perfusion (EVLP), which is an approved method of…
- Trial name
- NCT03112044
- Testing
- Sofosbuvir-velpatasvir (400 mg/100 mg), Ex Vivo Lung Perfusion (EVLP)
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University Health Network, Toronto
Cancer, Mindfulness-based Intervention
Effects of a Second-generation Mindfulness-based Intervention on Quality of Life, Pain Management, and Psycho-spiritual Wellbeing in Cancer Patients: A Randomised Controlled Trial
Background This study explores the effectiveness of Meditation Awareness Training (MAT), a second-generation mindfulness-based intervention, in enhancing quality of life, pain management, and psycho-spiritual wellbeing among…
- Conditions
- Cancer, Mindfulness-based Intervention, Meditation, Psychological Well-Being
- Trial name
- NCT06695234
- Testing
- Meditation Awareness Training
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Derby
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.