Clinical trials: Treatment as usual
Insomnia, Depression
Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents
Emerging encouraging evidence showed that sleep focused treatment can simultaneously improve sleep and depression in adult with comorbid conditions.
- Conditions
- Insomnia, Depression, Adolescent
- Trial name
- NCT06358898
- Testing
- Standard dCBT-I, Modified Mood enhanced CBT-I (M-dCBT-I)
- Where
- Hong Kong
- Volunteers
- 343 people
- Sponsor
- Chinese University of Hong Kong
Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30
Interest of Hypnosis When Setting up Non-invasive Ventilation in a Conscious Patient With COPD and/or Obesity With a BMI Greater Than 30, Suffering Fromacute Respiratory Distress in Adult Intensive Care
Discomfort during respiratory decompensation of a patient with chronic obstructive pulmonary disease (COPD) and/or obesity with a BMI greater than 30, in intensive care and the establishment of non-invasive ventilation (NIV) is…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30, Acute Respiratory Distress in Adult Intensive Care
- Trial name
- HYVIR (NCT04220463)
- Testing
- Hypnosis + NIV, NIV
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Obesity, Weight Loss
Does Use of the Voy Program Improve Weight Loss Percentage and Other Health Outcomes in a Population Already Taking GLP/GIP-1RA Medication?
The aim of the trial is to assess the impact of the Voy Program on weight loss and other health outcomes in an obese population already approved for GLP/GIP-1RA medication.
- Trial name
- VOYAGER (NCT06710587)
- Testing
- Voy Program
- Volunteers
- 470 people
- Sponsor
- Menwell Limited
Obesity
Effect of GLP-1 Receptor Agonists on Body Composition in Obesity: The Role of Dietary Protein Consumption in Muscle Mass Maintenance
This study investigates how weight-loss medications, specifically GLP-1 receptor agonists, affect body composition, with a special focus on preserving muscle mass in adults with obesity.
- Trial name
- LEAN-PRO GLP-1 (NCT07495904)
- Testing
- High Protein Dietary Intervention, Control (Standard Mediterranean Diet Counseling)
- Where
- 2 sites in Greece
- Volunteers
- 130 people
- Sponsor
- Hellenic Mediterranean University
Heart Failure
USC and Bodyport Remote Heart Failure Management Study
A feasibility study investigating the Bodyport virtual cardiac clinic vs usual care for outpatient heart failure management at Keck Medical Center of USC
- Trial name
- NCT04975633
- Testing
- Bodyport Cardiac Scale
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Southern California
Non-suicidal Self-injury
Treatment for Non-Suicidal Self-Injury in Young Adults
The purpose of this study is to investigate an intervention specifically for non-suicidal self-injury (NSSI) in young adults. The goal of this 9-session outpatient intervention is to reduce the frequency and severity of NSSI.
- Trial name
- T-SIB (NCT01018433)
- Testing
- T-SIB, Treatment as usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fordham University
At Risk Mental State (ARMS), Psychosis
Minocycline and/or Omega-3 Fatty Acids Added to Treatment as Usual for At Risk Mental States
This is a randomized double-blind placebo controlled trial which aims to evaluate the efficacy and tolerability of minocycline and Omega-3 fatty acids for patients with ARMS.
- Trial name
- NAYAB (NCT02569307)
- Testing
- Minocycline, Omega-3 fatty acids, Minocycline Plus Omega-3 fatty acids
- Where
- 7 sites in Pakistan
- Volunteers
- 326 people
- Sponsor
- Pakistan Institute of Living and Learning
Depression, Coronary Disease
Treatment of Depression After Coronary Bypass Surgery
This randomized controlled trial will test the efficacy of (1) cognitive behavior therapy and (2) supportive stress management as treatments for depression in people who have recently undergone coronary artery bypass graft…
- Trial name
- NCT00042198
- Testing
- Cognitive behavior therapy, Supportive Stress Management
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Washington University School of Medicine
Post-Traumatic Stress Disorder
Trauma-focused Cognitive-behavioural Therapy(TF-CBT) for Children: A Study of Process and Outcome.
The purpose of this study is to determine whether Trauma focused cognitive behavioral therapy (TF-CBT)is more effective in the treatment of traumatized youth than treatment as usual(TAU).
- Trial name
- NCT00635752
- Testing
- TF-CBT, Treatment as Usual (TAU)
- Where
- Norway
- Volunteers
- 156 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Psychological Trauma, Stress Disorders, Post-Traumatic; Mental Disorders
Trauma-Focused Group Therapy for Adults With Trauma-Related Symptoms in Primary Care
Psychological trauma is common and can lead to long-lasting emotional distress, difficulties in daily functioning, and reduced quality of life.
- Trial name
- NCT07757334
- Testing
- Trauma-Focused Group Intervention, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Luis Eduardo Estévez Cachafeiro
Post Traumatic Stress Disorder, Depression
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees
INTRODUCTION Trauma-affected refugees are at high risk of developing mental health problems including post-traumatic stress disorder (PTSD) and depression.
- Conditions
- Post Traumatic Stress Disorder, Depression, Psychosocial Problem
- Trial name
- NCT04244864
- Testing
- Cross-sectoral psychosocial intervention, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 196 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Depression, Anxiety
T.E.A.M. Feasibility and Efficacy Study 2.0
T.E.A.M. psychotherapy was developed by one of the founders of cognitive therapy, David Burns and builds on traditional CBT with an emphasis on T = Testing, E = Empathy, A = Agenda Setting (assessing and building motivation) and…
- Trial name
- TEAM (NCT03694106)
- Testing
- TEAM PSYCHOTHERAPY
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Feeling Good Institute
Opioid-use Disorder, Opioid Use
PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers
The objective of this research is to assess the effects of electronic health record (EHR)-based decision support tools on primary care provider (PCP) decision-making around pain treatment and opioid prescribing.
- Conditions
- Opioid-use Disorder, Opioid Use, Opioid Abuse
- Trial name
- PRINCE (NCT04601506)
- Testing
- Choice Architecture Nudge, PMP Integration & Nudge
- Where
- United States
- Volunteers
- 472 people
- Sponsor
- University of Minnesota
Esophageal Cancer
Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy
The purpose of this study is to test whether after an Ivor Lewis esophagectomy (the removal of a portion of the stomach and esophagus with re-attachment) there is an association between the intraoperative level of oxygen at the…
- Trial name
- NCT01551433
- Testing
- wireless pulse oximeter (Wipox)
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Mental Health Wellness 1
The Effects of Trauma-sensitive Yoga and Tai Chi on Mental Health
A three-arm randomized control trial design was used to test the effectiveness of (1) Chen Style Tai Chi (TC) and talk therapy; (2) Trauma-Sensitive Yoga and talk therapy in comparison to (3) talk therapy only (control group) on…
- Trial name
- TSY/TC (NCT04754009)
- Testing
- Trauma-Sensitive Yoga + TAU, Chen Style Tai Chi + TAU, Treatment as Usual
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Behavioral Symptoms, Emotional Instability
Emotion Regulation Group Skills Training for Adolescents and Parents
To evaluate if emotion regulation group therapy skills training for adolescents and parents is an efficacious treatment when delivered as adjunctive to treatment as usual compared to a control group consisting of treatment as…
- Trial name
- NCT03900533
- Testing
- Adjunctive group emotion regulation skills training, Treatment as usual
- Where
- Sweden
- Volunteers
- 119 people
- Sponsor
- Region Östergötland
Depression
A Computerized Depression Intervention in Veterans
Depressive symptoms are common among Veterans and associated with significant impairment. Timely intervention has the potential to improve mental health outcomes and restore functioning.
- Trial name
- Deprexis (NCT06217198)
- Testing
- Deprexis
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
Chronic Disease, Lung Diseases, Obstructive
Home-based Exercise Training for COPD Patients
The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who have completed a pulmonary rehabilitation.
- Conditions
- Chronic Disease, Lung Diseases, Obstructive, Respiratory Disease
- Trial name
- HOMEX-1 (NCT03461887)
- Testing
- Exercise
- Where
- 5 sites in Switzerland
- Volunteers
- 123 people
- Sponsor
- University of Zurich
Breast Cancer, Women
Evaluation of the Effects of the Couple-based Family Nursing for Women With Breast Cancer
The women with breast cancer and their spouses experienced physical and mental distresses together, nevertheless, the spouses were the significant supporters for patients during post-surgery rehabilitation.
- Conditions
- Breast Cancer, Women, Mastectomy, Breast-Conserving Surgery
- Trial name
- NCT05100914
- Testing
- Couple-based family nursing
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Defense Medical Center, Taiwan
Diabetes
Hypoglycemia Prevention in High-Risk Type 2 Diabetes Patients
Severe low blood sugar (hypoglycemia) is a serious problem for people with diabetes. It can lead to dangerous falls, heart problems, memory issues, and even death.
- Trial name
- NCT06746714
- Testing
- Proactive population care (active application of HOAP principles in patients flagged as high risk for hypoglycemia), Usual care, after system-side dissemination of HOAP
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Kaiser Permanente
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