Clinical trials: Treatment as usual
Posttraumatic Stress Disorder
Improving Function Through Primary Care Treatment of Posttraumatic Stress Disorder (PTSD)
The proposed project will examine a promising brief therapy for posttraumatic stress Disorder (PTSD) for use in Veterans Health Administration (VHA) Primary Care and its impact on functional outcomes.
- Trial name
- PE-PC (NCT03581981)
- Testing
- Prolonged Exposure for Primary Care (PE-PC), Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Treatment Satisfaction, Participation Rate, Patient
Mindfulness Based Stress Reduction for Intellectually Able Autistic Adults
This project evaluates mindfulness based stress-reduction (MBSR), adjusted and manualized for intellectually able autistic adults. MBSR is a skills training program based on further development of cognitive behavioral therapy.
- Conditions
- Treatment Satisfaction, Participation Rate, Patient, Quality of Life, Mental Illness
- Trial name
- NCT05244265
- Testing
- Mindfulness-based stress reduction (MBSR), Treatment as usual (TAU)
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Independent Child Migration
Intervention to Improve Developmental and Health Outcomes for Female Adolescents
The primary goal of this pilot study (R21) is to address the urgent need for theoretically and empirically informed interventions that prevent poor female youth's rural-to-urban migration for child labor in low and middle-income…
- Trial name
- NCT04231669
- Testing
- Anzansi Family Program
- Where
- Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depressive Disorder
Imaging to Improve Brain Stimulation
This study investigates how brains change as a result of a treatment for depression called repetitive transcranial magnetic stimulation (rTMS).
- Trial name
- NCT04016402
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Burnout, Perceived Stress
The Effect of Laughter Yoga on Stress, Burnout, and General Health in Psychiatric Nurses
This study aims to examine the effects of laughter yoga on general health, perceived stress, and burnout among psychiatric nurses.
- Conditions
- Burnout, Perceived Stress, Occupational Stress, General Health
- Trial name
- NCT07015372
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bezmialem Vakif University
Anxiety, Depression Disorders
Enhanced Ward Rounds and Communication for Pre-procedural Anxiety in GI Endoscopy Patients
This study tests a new way to help reduce anxiety in hospitalized patients waiting for therapeutic gastrointestinal (GI) endoscopy procedures, like EMR or ESD.
- Conditions
- Anxiety, Depression Disorders, Sleep Wake Disorders, Gastrointestinal Diseases
- Trial name
- NCT07286877
- Testing
- Enhanced Ward-Round Frequency With Standardized Communication, Usual Care Ward Rounds (2/day)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- LanZhou University
Type 2 Diabetes, Hypertension
Impact of Clinical Pharmacist-Led Intervention on Management of Diabetic Hypertensive Patients in Eastern Nepal
Diabetic-Hypertensives are at a higher risk of premature microvascular and macrovascular complications than diabetes alone. Proper lifestyle management, diet, disease monitoring, and medication adherence is essential in achieving…
- Trial name
- NCT05707481
- Testing
- Clinical Pharmacist-Led Educational Intervention
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Chettinad Academy of Research and Education (Deemed to be University)
Schizophrenia, Schizoaffective Disorder
RCT of Methotrexate Added to Treatment As Usual in Schizophrenia
The aim of the this study is to evaluate the effectiveness of methotrexate added to treatment as usual on positive and negative symptoms, cognitive and social functioning and quality of life of patients suffering from…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- RECOVERY (NCT02074319)
- Testing
- Methotrexate
- Where
- 4 sites in Pakistan
- Volunteers
- 92 people
- Sponsor
- Pakistan Institute of Living and Learning
Obesity
MOTIVOB-(Acceptance and Commitment Therapy Group Intervention for Obesity)Section
The purpose of the present study is to compare an Acceptance and Commitment Therapy (ACT) group intervention and a Cognitive Behavioral Therapy (CBT) group in a sample of obese individuals with respect to mid-term outcome.
- Trial name
- MOTIVOB-ACT (NCT03066531)
- Testing
- ACT-based intervention, CBT-based intervention
- Volunteers
- 156 people
- Sponsor
- Istituto Auxologico Italiano
Emotional Disorder, Anxiety Disorders
The Unified Protocol for the Treatment of Emotional Disorders in Spanish Public Mental Health System
The present randomized, controlled trial will compare the cost-efficacy and acceptability of the Unified Protocol in group format against traditional individual Cognitive Behavioral Treatment in a sample of patients with…
- Conditions
- Emotional Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT03064477
- Testing
- Unified Protocol, Cognitive Behavioral Therapy (TAU)
- Where
- 3 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Universitat Jaume I
Suicide
Culturally Centered CBT for Latinx Youth
The primary aim of the proposed research is to test the effect of a culturally centered treatment protocol, the Socio-cognitive behavioral therapy (SCBT), versus Treatment as Usual on suicidal thoughts and attempts, and…
- Trial name
- NCT04278157
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- Bradley Hospital
Healthy Volunteers
A Controlled-Feeding Study to Assess the Effect of Cashews on Fasting Lipoprotein Levels
This study will assess the nutritional effect of cashews on LDL-C concentrations and secondarily on other aspects of the fasting lipoprotein lipid profile in healthy men and women with moderately elevated cholesterol.
- Trial name
- NCT02769741
- Testing
- Cashews followed by Control, Control followed by Cashews
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kraft Heinz Company
Alcohol Use Disorder
Brief Motivational Therapy Versus Usual Care for Alcohol Use Disorders in Primary Care.
Harmful alcohol use is a leading cause of global disability and death. However increased detection and brief intervention capacity of more severe alcohol use disorders (AUD) has not been accompanied by increased availability of…
- Trial name
- NCT04345302
- Testing
- Brief motivational treatment, Enhanced Usual Care
- Where
- 3 sites in Chile
- Volunteers
- 182 people
- Sponsor
- Nicolás Barticevic
Psychological Stresses
Strengths-Based Family Psychoeducation for Youth Psychosis
The onset of Psychosis forces family members to bear a heavy burden of care. The mental well-being of the family is so complicated that it is important to relieve their psychological stresses.
- Trial name
- NCT01731977
- Testing
- Strengths-based family psychoeducation
- Where
- 4 sites in Japan
- Volunteers
- 74 people
- Sponsor
- Nagoya City University
Schizophrenia
Application of a Mindfulness and Self-Compassion Program in Patients With Schizophrenia. Randomized Controlled Trial.
This is a randomized clinical trial to check whether the quality of life of patients with schizophrenia improves after participation in the mindfulness and self-compassion (MSC) programme.
- Trial name
- ACAMP2020 (NCT04144075)
- Testing
- Mindful Self-Compassion Program, Cognitive Behaviour Therapy Group, Treatment as usual
- Volunteers
- 150 people
- Sponsor
- Gutiérrez-Hernández, ME
Anxiety Depression
Mindfulness-Based Art Therapy and Generation Z
A randomized controlled trial will be conducted to determine the unique role of the arts as a proactive mental health strategy for college students in Generation Z.
- Trial name
- NCT04834765
- Testing
- Mindfulness-based art therapy, Art-only, Mindfulness-only
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Florida State University
Mild Cognitive Impairment, Depressive Symptoms
HEPPI: Efficacy of a Cognitive-Emotional Intervention for Homebound Older Adults
The main goal of this research is to assess the efficacy of a 10-week home-delivered cognitive-emotional intervention program for homebound older adults presenting Mild Cognitive Impairment (MCI) and depressive and/or anxiety…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT05499767)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 199 people
- Sponsor
- University of Coimbra
Gout, Arthritis, Obesity
Weight Loss for Obese Individuals With Gout
This study evaluates effect of weight loss in a group of obese patients with gouty arthritis. The study is a randomised group trial where half the patients receive intensive weight loss in the form of meal replacement from…
- Trial name
- NCT03664167
- Testing
- intensive weight loss diet, with Cambridge weightplan products, and visits to a dietician.
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Henning Bliddal
All International Classification of Primary Care 2 Diagnoses
Effect Evaluation of Independent Medical Evaluation (IME) in Norway
A randomized controlled trial comparing independent medical evaluation (IME) to treatment as usual (TAU). Participants will be individuals reaching six months uninterrupted sickness absence.
- Trial name
- NIME (NCT02524392)
- Testing
- Independent medical evaluation
- Where
- Norway
- Volunteers
- 7,642 people
- Sponsor
- NORCE Norwegian Research Centre AS
Depressive Disorder, Depression
Mindfulness Based Emotion Regulation Therapy in the Treatment of Depressive Rumination
In this study the investigators are examining the neuronal processes of a mindfulness based emotion regulation training for reducing depressive rumination.
- Conditions
- Depressive Disorder, Depression, Rumination
- Trial name
- NCT04560192
- Testing
- Mindfulness based Emotion regulation therapy (MBERT) - Treatment as usual (TAU), Treatment as usual (TAU) - Mindfulness based Emotion regulation therapy (MBERT)
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
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