Clinical trials: Treatment as usual
Type 2 Diabetes
Rural Area Pharmacist Intervention for Diabetes
The goal of the project is to inform the system leaders regarding the feasibility and utility of having an embedded telehealth-based clinical pharmacist at rural primary care practices for supportive disease management of…
- Trial name
- NCT05761886
- Testing
- telehealth-based clinical pharmacy intervention
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Wake Forest University Health Sciences
Family, Parenting
Pilot Trial of Family Partner - a Child Maltreatment Prevention Intervention
Prior to this pilot study, it is unclear whether comparing a manualized version of the Family Partner Model to standard practice in the Child Welfare Services would be feasible.
- Conditions
- Family, Parenting, Child Maltreatment
- Trial name
- FAMPART (NCT04957394)
- Testing
- Family Partner
- Where
- 3 sites in Norway
- Volunteers
- 45 people
- Sponsor
- Oslo Metropolitan University
Oral Health, Parkinson Disease
Preliminary Study of the Quality of the Oral Flora in Parkinson's Patients
This is a prospective interventional clinical study whose main objective is to determine the impact of oral hygiene guidance on the oral health status of patients with Parkinson disease
- Trial name
- PARKIDENT (NCT03827551)
- Testing
- Delivery of oral hygiene advices
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Atherosclerotic Cardiovascular Disease, Cardiovascular Disease
Intima-Medial Thickness Guidance of Primary Prevention in Relatives of Patients With Early onSet Atherosclerosis
The primary objective of this study is, to instigate a reduction in atherosclerotic burden within the carotid arteries in the intervention group compared to the control group and to demonstrate parallel improvements in…
- Trial name
- IMPRESS (NCT01330602)
- Testing
- IMPRESS intervention
- Where
- 3 sites in Singapore
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Varicose Ulcer
Effectiveness and Efficiency of Two Models of Delivering Care to a Chronic Wound Population
Individuals referred to home care for leg ulcer management were randomized to nurse home visits (usual care) or nurse-run community clinics (intervention). The primary outcome will be the time to healing rates at three months.
- Trial name
- NCT00656383
- Testing
- Clients randomized to nurse-led clinic, Clients receive leg ulcer care in their homes
- Where
- 2 sites in Canada
- Volunteers
- 401 people
- Sponsor
- Queen's University
Gait, Unsteady
Home-based Motor Imagery for Gait Stability in Older Adults. A Cross-over Feasibility Study. (MIGS-F)
Gait stability is reduced as early as from age 40 to 50. Gait stability can be improved in patients with neurological diseases or in healthy elderly persons with exercises.
- Trial name
- MIGS-F (NCT02693756)
- Testing
- Motor imagery
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences of Western Switzerland
Opiate Dependence
Linking Hospitalized Injection Drug Users to Buprenorphine
This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a "link") for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV…
- Trial name
- NCT00987961
- Testing
- Linkage
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Butler Hospital
Psychosis
Strategic Timing of Resistance Training to Guard Against Antipsychotic-Induced Metabolic Syndrome
This study is evaluating whether a supervised resistance training (strength training) programme is feasible to perform in a first-episode psychosis service.
- Trial name
- START GAAIMS (NCT07386483)
- Testing
- Resistance training programme
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Dublin
Long COVID, Pain
Effects of an Active Coping Program in Patients With Persistent Post-Covid Pain.
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Previous studies carried out by this research group and in the scientific literature have shown that…
- Trial name
- NCT05894629
- Testing
- Pain Neuroscience Education (PNE)+ Therapeutic Exercise (TE), Active Comparator: Usual treatment
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- University of Valladolid
Bipolar Disorder, Caregiver Burden
Evaluation of Efficiency of One Day Patient/Caregiver Psychoeducation on the Caregiver's Burden
Bipolar disorder (BD) has a huge impact on the lives of patient and their relatives. Psychoeducation programs on BD has been shown to be effective on the burden of patients and their caregivers.
- Trial name
- BP ONEDAY (NCT05178966)
- Testing
- Bp OneDay psychoeducation program
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Obesity
Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic
Research purpose: The purpose of this pilot study is to assess obese clients for two phenotypes, those testing positive and those testing negative for Food Addiction (FA) (Yale Food Addiction Scale, YFAS) and determining the…
- Trial name
- NCT03431831
- Testing
- Intervention Control, Counselling, Contrave
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Heart Failure NYHA Class IV, Heart Failure NYHA Class II
Impact of Sacubitril/Valsartan on Quality of Life and Mortality of CKD vs Non-CKD in Heart Failure Patients
The two primary goals of it's management are preventing further disease progression(mortality,hospitalizations and deterioration of left ventricular function)and alleviating patient suffering
- Trial name
- NCT04218435
- Testing
- Sacubitril / Valsartan Oral Tablet
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Clinision
Inflammatory Bowel Diseases, Ulcerative Colitis
IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
This research study is testing whether changes in sleep timing and morning light treatment may have an impact on symptoms related to inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT06094608
- Testing
- Morning light treatment, Treatment-as-usual
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Michigan
Postpartum Depression, Postpartum Anxiety
A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital
This study is a pilot, single-center, randomized controlled trial. It will 1. determine feasibility and acceptability of an evidence-based intervention for prevention of postpartum depression with antepartum patients on a…
- Trial name
- NCT05225025
- Testing
- ROSE, Standard of Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester
Heart Failure
Guiding Evidence Based Therapy Using Biomarker Intensified Treatment
The primary objective is to determine the efficacy of a strategy of biomarker-guided therapy compared with usual care in high risk patients with left ventricular systolic dysfunction.
- Trial name
- GUIDE-IT (NCT01685840)
- Testing
- Usual Care, Biomarker-guided care NT-proBNP
- Where
- 46 sites in United States, Canada
- Volunteers
- 894 people
- Sponsor
- Duke University
Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM)
Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)
GOLD-STANDARD is a pragmatic, open-label pilot randomized controlled trial evaluating the feasibility, safety, and implementation of an early goal-directed Cardio-Kidney-Metabolic (CKM) care strategy compared with usual care in…
- Conditions
- Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease
- Trial name
- GOLD-STANDARD (NCT07434791)
- Testing
- Early goal-directed Cardio-Kidney-Metabolic (CKM) care, Standard care (Comparison arm)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Migraine Disorders
A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents
Migraine is a neurological disease characterized by severe and recurrent headaches. Children and adolescents with migraine often present to the emergency department (ED) with acute attacks, where migraine accounts for up to ~30%…
- Trial name
- NCT05102591
- Testing
- Ketorolac, Metoclopramide, Active Remote Electrical Neuromodulation Device
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Hypertension
A Pilot Study of Hypertension Management Using Remote Patient Monitoring
The investigators will conduct a pragmatic pilot test of a remote patient monitoring system (RPM) for blood pressure measurement for Medicare patients with hypertension.
- Trial name
- NCT04604925
- Testing
- Remote patient monitoring for hypertension
- Where
- United States
- Volunteers
- 7,068 people
- Sponsor
- Northwestern University
Opioid-Related Disorders
Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings
In preparation for a large-scale randomized controlled trial (RCT) of Vivitrol® effectiveness in drug courts, investigators propose a feasibility study in the Wake County, North Carolina drug court, where an estimated 50% of…
- Trial name
- DC (NCT02978417)
- Testing
- Naltrexone for extended-release injectable suspension, Oral naltrexone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Interstitial Cystitis, Levator Spasm
A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain
The goal of this clinical trial is to compare two different treatment patterns in patients with chronic bladder pain. The main questions the investigators are seeking to answer is if bladder pain improves before and after…
- Conditions
- Interstitial Cystitis, Levator Spasm, Bladder Pain Syndrome
- Trial name
- NCT05658874
- Testing
- Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jocelyn Fitzgerald
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