Clinical trials: Treatment as usual
Multiple Sclerosis, Relapsing-Remitting, Pain, Chronic
The Effects of Relaxation Techniques on Pain, Fatigue and Kinesiophobia in Multiple Sclerosis Patients: A Three Arms Randomized Trial
Even though, current treatments including IVIG, corticosteroids, biological agents can provide positive effects on MS symptoms, MS cannot be cured completely today.
- Conditions
- Multiple Sclerosis, Relapsing-Remitting, Pain, Chronic, Fatigue Syndrome, Chronic, Kinesiophobia
- Trial name
- NCT04833673
- Testing
- PMR: Progressive Muscle Relaxation, BRT:Benson Relaxation Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Generalized Anxiety Disorder
Pivotal RCT to Test Safety and Efficacy of Digital Therapeutics 'ANZEILAX' for Managing Generalized Anxiety Disorder
The investigators propose to develop and adapt 'ANZEILAX' smartphone app specifically for individuals with Generalized anxiety disorder.
- Trial name
- NCT06010654
- Testing
- Software as a Medical device
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- HAII corp.ltd
Ventilator Associated Pneumonia
Impact of Imipenem With Amikacin Pharmacokinetic and Pharmacodynamic
The study is a prospective open trial conducted in 4 centers, and designed to determine if pharmacokinetic (PK) and pharmacodynamic (PD) parameters of imipenem, associated with amikacin as empirical therapy, impact…
- Trial name
- IMPACT (NCT00950222)
- Testing
- Imipenem/Amikacin
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain Injuries, Acquired Brain Injury
Human-Animal Interaction to Promote Recovery Following Pediatric Brain Injury
This study evaluates the addition of therapy dogs in inpatient physical and occupational therapy. Data will be collected across 10 PT and 10 OT sessions, half of which will incorporate a therapy dog.
- Conditions
- Brain Injuries, Acquired Brain Injury, Traumatic Brain Injury
- Trial name
- AAT (NCT04016961)
- Testing
- AAT - Dog, TAU - No Dog
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Pain, Headache
Provider-Targeted Behavioral Interventions to Prevent Unsafe Opioid Prescribing for Acute Pain in Primary Care
The investigators will assess whether behavioral science-based interventions can "nudge" providers towards more evidence-based care for patients with acute non-cancer pain.
- Conditions
- Acute Pain, Headache, Musculoskeletal Pain
- Trial name
- NCT03537573
- Testing
- Usual Care/Guideline, Opioid Justification, Provider Comparison
- Where
- United States
- Volunteers
- 22,616 people
- Sponsor
- University of Pittsburgh
Alzheimer Disease, Cognitive Dysfunction
Effect of Scene-Based Training on Cognitive Function in Patients With Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, including impairments in orientation, memory, and daily functioning.
- Conditions
- Alzheimer Disease, Cognitive Dysfunction, Mild Cognitive Impairment
- Trial name
- NCT07548073
- Testing
- Scenario-Based Reenactment Training, Usual Care
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Distress, Anxiety
Mobilized Psychoeducation and Skills Based Intervention (Pep-Pal) for Caregivers of Patients With Advanced Illness
The proposed project is a pilot study of the Pep-Pal (Psychoeducation and Skills Based Intervention) versus a treatment as usual control group.
- Conditions
- Distress, Anxiety, Depression
- Trial name
- NCT03002896
- Testing
- Pep-Pal, Treatment as Usual
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cephalalgia
Protocol to Ease Acute Cephalalgia in Emergency-department
The purpose of this study is to determine if the use of a therapeutic and global protocol to relieve cephalalgia is helpful in the emergency department of Grenoble University Hospital.
- Trial name
- PEACE (NCT02236442)
- Testing
- Recommendation to use global headache treatment protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Family Members
Improving Family Engagement in Coordinated Specialty Care for First Episode Psychosis
Investigators aim to develop and evaluate a culturally informed family motivational engagement strategy (FAMES) and implementation toolkit for coordinated specialty care (CSC) programs for first episode psychosis.
- Trial name
- NCT04188366
- Testing
- FAMES, Treatment-as-Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington State University
Mental Illness
Medication Free Treatment: Characteristics, Justification and Outcome
In 2015 the Norwegian government, after initiative from user organizations, decided to implement medication free inpatient treatment units.
- Trial name
- NCT03499080
- Testing
- Medication free treatment, Treatment as usual Myrvegen, Treatment as usual Åråsen
- Where
- 2 sites in Norway
- Volunteers
- 183 people
- Sponsor
- University Hospital, Akershus
Chronic Pain, Nociplastic Pain
Multimodal Lifestyle Approach for Chronic Pain With Nociplastic Pain Features
This single-center, single-arm pilot feasibility study aims to examine the feasibility and preliminary effectiveness of an intervention program using a pain education booklet based on a multimodal lifestyle approach for patients…
- Trial name
- MLA-MM (NCT07693062)
- Testing
- Multimodal Lifestyle Approach Using a Pain Education Booklet
- Where
- 2 sites in Japan
- Volunteers
- 15 people
- Sponsor
- Prefectural University of Hiroshima
Urinary Incontinence, Vulvar Pruritus
Vulvar Contact Dermatitis Resulting From Urine Incontinence
Vulvar contact dermatitis (VCD) is a common problem presenting as vulvar pruritus, burning or irritation. Its estimated prevalence is 20-30% in vulvar clinics, but the prevalence in the general population is unknown.
- Conditions
- Urinary Incontinence, Vulvar Pruritus, Vulvar Contact Dermatitis
- Trial name
- NCT01320046
- Testing
- Questionnaires, gynecological exam , vaginal smear, and measurement of urine leakage
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center
Chronic Pain, Pain
Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"
Chronic pain is a significant public health problem that affects over 116 million Americans, costs $600 billion annually, and is unequally borne by people in low-income brackets, especially ethnic minorities.
- Conditions
- Chronic Pain, Pain, Widespread Chronic Pain, Chronic Pain Syndrome
- Trial name
- LAMP (NCT01967342)
- Testing
- Pain Ed, CBT for Pain, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- University of Alabama, Tuscaloosa
Anger
Effectiveness of Anger Management Treatment in Reducing Anger-Related Behaviors in Female Juvenile Offenders
This study will evaluate the effectiveness of an anger management treatment program, Juvenile Justice Anger Management for Girls, in reducing anger-related behaviors displayed by girls in the juvenile justice system.
- Trial name
- NCT00720486
- Testing
- Juvenile Justice Anger Management (JJAM) for Girls, Treatment as usual
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- naomi goldstein
Autism Spectrum Disorder
Intervention for Toddlers at Risk for Autism Spectrum Disorders (ASD)
This research is being done to test the effectiveness of an early intervention model for very young children at high risk for autism spectrum disorders (ASD) and their families.
- Trial name
- NCT01179841
- Testing
- Playgroup, Parent Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Trauma, Psychological, Sexual Violence
CFT Self-Help for Accessing Cervical Screening After Sexual Assault
The aim of this study is to evaluate the feasibility of a new self-help intervention designed to support individuals (anyone with a cervix) to access cervical cancer screening following the experience of sexual assault, by…
- Conditions
- Trauma, Psychological, Sexual Violence, Cervical Cancer
- Trial name
- NCT04104724
- Testing
- Self-help
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Migraine
Effectiveness of a Dialogue-based Online Intervention Against Migraine
This trial was designed to evaluate the effectiveness of a dialogue-based online intervention (ceprica) that provides information regarding cognitive behavioural therapy (CBT) in patients with migraine.
- Trial name
- EU-OPTMi (NCT04276142)
- Testing
- ceprica (additional to treatment as usual), active control intervention (additional to treatment as usual)
- Where
- Germany
- Volunteers
- 321 people
- Sponsor
- Gaia AG
Type 1 Diabetes Mellitus, Diabetes Self-Management Education
DiaBuddy: AI-Enabled Digital Self-Management for Youth With Type 1 Diabetes
The goal of this clinical trial is to learn whether DiaBuddy, a digital self-management app, can help children and adolescents with Type 1 diabetes better manage their condition and reduce the burden experienced by their…
- Conditions
- Type 1 Diabetes Mellitus, Diabetes Self-Management Education, Caregiver Burden
- Trial name
- DiaBuddy (NCT07861373)
- Testing
- DiaBuddy: AI-Enabled Digital Self-Management Intervention, Usual Diabetes Care
- Volunteers
- 140 people
- Sponsor
- Dr. Juwayria Omar
Post Traumatic Stress Disorder, Schizophrenia
PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
As in the general population, there is no clear standard of care within Veterans Affairs Medical Centers for treating posttraumatic stress disorder (PTSD) among individuals with severe mental illness (SMI).
- Conditions
- Post Traumatic Stress Disorder, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- PTSD/SMI (NCT01542229)
- Testing
- Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Psychosis, Schizophrenia
ReMindCare App for Patients From First Episode of Psychosis Unit.
ReMindCare is an app designed by the Unit of Psychiatry at the Clinical Hospital of Valencia in liaison with the Polytechnic University of Valencia.
- Conditions
- Psychosis, Schizophrenia, Psychotic Disorders, Delirium
- Trial name
- NCT03807388
- Testing
- ReMindCare Intervention Group, Treatment as Usual
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Instituto de Investigacion Sanitaria INCLIVA
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