Clinical trials: Treatment as usual
Radiculopathy of Lumbosacral Spine Due to Disc Disorder
Short-term Effectiveness of Gabapentin Versus Placebo in Acute Lumbosacral Radiculalgia by Herniation Disc (GRADE)
The study consists in evaluating the analgesic efficacy of Gabapentin versus Placebo in the short term (72h) acute lumbosacral radiculalgia due to disc herniation.
- Trial name
- GRADE (NCT04865042)
- Testing
- Gabapentin 300mg
- Where
- 5 sites in France
- Volunteers
- 144 people
- Sponsor
- Lille Catholic University
Diabetes, Covid-19
Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized Patients
This is a randomized controlled trial of isolated patients with diabetes admitted to Nordsjællands Hospital with or without COVID-19-pneumonia.
- Conditions
- Diabetes, Covid-19, Infection
- Trial name
- CGM-ISO (NCT04430608)
- Testing
- Dexcom G6
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Nordsjaellands Hospital
Systemic Lupus Erythematosus, Medication Adherence
Effectiveness of Pharmaceutical Care in the Adherence of Systemic Lupus Erythematosus Treatment
This project aims to improve adherence rate through pharmaceutical care in patients with systemic lupus erythematosus (SLE) to help achieving therapeutic goals and finally to improve the quality of life of these patients.
- Trial name
- ADELES (NCT02330250)
- Testing
- Pharmaceutical Care, Control
- Where
- Brazil
- Volunteers
- 131 people
- Sponsor
- Oswaldo Cruz Foundation
Chronic Obstructive Pulmonary Disease (COPD), Allergies
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies.
- Trial name
- COPD-OMA (NCT07059091)
- Testing
- Omalizumab (Xolair®), Sodium Chloride (NaCl) 0.9 %
- Where
- 23 sites in United States
- Volunteers
- 334 people
- Sponsor
- Johns Hopkins University
Psychological Stress, Life Stress
Personalized Support for Progress (PSP) in a VA Women's Wellness Clinic
The purpose of this study is to evaluate the Personalized Support for Progress (PSP) intervention in a Veterans Health Administration (VHA) Women's Wellness Clinic.
- Conditions
- Psychological Stress, Life Stress, Emotional Stress
- Trial name
- NCT03908190
- Testing
- Personalized Support for Progress
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Syracuse VA Medical Center
Aphasia, Aphasia, Anomic
Speech Therapy and Repetitive Transcranial Magnetic Stimulation Therapy in Post-stroke Anomic Aphasia
The aim of the study is to observe the effects of speech therapy and transcranial magnetic stimulation therapy in patients who develop anomic aphasia after stroke.
- Conditions
- Aphasia, Aphasia, Anomic, Stroke
- Trial name
- NCT04625790
- Testing
- Repetitive transcranial magnetic stimulation, Speech therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Ege University
Covid19, Vitamin D Deficiency
High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study
The world is currently facing a pandemic with the coronavirus (SARS-CoV-2) which leads to the disease of COVID-19. Risk factors for a poor outcome of COVID-19 have so far been identified as older age and co-morbidity including…
- Conditions
- Covid19, Vitamin D Deficiency, Corona Virus Infection, ARDS
- Trial name
- VitCov (NCT04525820)
- Testing
- Single high dose vitamin D, Treatment as usual vitamin D
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Prof. Dr. Jörg Leuppi
Schizophrenia, Diabetes
Medication Reviews in Severe Mental Illness
This study aims to investigate the potential beneficial effects of a medication review by a clinical pharmacologist on patients with coexisting severe mental illness and diabetes.
- Conditions
- Schizophrenia, Diabetes, Metabolic Syndrome, Severe Mental Disorder
- Trial name
- NCT05243160
- Testing
- medication review
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Benzodiazepine Dependence, Benzodiazepine Dependent
Blended Care for the Discontinuation of Benzodiazepine Use
This study aims to compare two strategies performed by GPs to help patients taking benzodiazepines on a daily basis for at least six months to discontinue their use.
- Conditions
- Benzodiazepine Dependence, Benzodiazepine Dependent, Benzodiazepine Withdrawal
- Trial name
- Big Bird (NCT03937180)
- Testing
- Blended care, Usual care
- Where
- 110 sites in Belgium
- Volunteers
- 924 people
- Sponsor
- Kristien Coteur
Lung Cancer
Supportive Care for Patients Newly Diagnosed With Lung Cancer
The aims of this project are to assess the feasibility of recruiting patients and delivering a nurse-led telephone based palliative care intervention for patients with newly diagnosed lung cancer and to assess if among patients…
- Trial name
- NCT01883986
- Testing
- Palliative Care
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- VA Office of Research and Development
Hypertension, High Blood Pressure
Efficient Self-management of Chronic Disease Using Health Information Technology - a Study on Hypertension
Background: Hypertension is an increasing global problem and measures are needed against the emerging hypertensive burden. Management of the risk factor hypertension consists of medical treatment in conjunction with lifestyle…
- Trial name
- PERHIT (NCT03554382)
- Testing
- system to support self-management of hypertension
- Where
- 4 sites in Sweden
- Volunteers
- 971 people
- Sponsor
- Region Skane
Intensive Care Unit Acquired Weakness (ICUAW)
eStimCycle: Early Rehabilitation in Critical Care
Project Summary: Patients who have a length of stay four or more days in ICU and requiring mechanical ventilation assistance to breathe for more than 48 hours will be invited to participate.
- Trial name
- eStimCycle (NCT02214823)
- Testing
- FES-Cycling, Standard Care
- Where
- 4 sites in United States, Australia
- Volunteers
- 162 people
- Sponsor
- Associate Professor Sue Berney PhD, BPT
Mental Illness
Medication Free Treatment: Characteristics, Justification and Outcome
In 2015 the Norwegian government, after initiative from user organizations, decided to implement medication free inpatient treatment units.
- Trial name
- NCT03499080
- Testing
- Medication free treatment, Treatment as usual Myrvegen, Treatment as usual Åråsen
- Where
- 2 sites in Norway
- Volunteers
- 183 people
- Sponsor
- University Hospital, Akershus
Multiple Sclerosis
Study of the Mechanisms of Action of Cladribine in Multiple Sclerosis
The main objective of the project is therefore to study and thus better understand the immunomodulatory / anti-inflammatory effects of cladribine during multiple sclerosis.
- Trial name
- Clad'Action (NCT04821596)
- Testing
- biological collection
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Rouen
Opiate Dependence
Linking Hospitalized Injection Drug Users to Buprenorphine
This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a "link") for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV…
- Trial name
- NCT00987961
- Testing
- Linkage
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Butler Hospital
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice
Baby2Home (B2H) Mobile Health Application
The COVID-19 pandemic has transformed healthcare delivery; arguably, the fields of obstetrics and pediatrics have experienced some of the greatest changes as they have transitioned away from their role as a medical home and into…
- Conditions
- COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness
- Trial name
- NCT05595486
- Testing
- Baby2Home Mobile Application
- Where
- 2 sites in United States
- Volunteers
- 642 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Diabetes Mellitus, Diabetes Mellitus, Type 2
Evaluation of a Dashboard for Diabetes Care Integrated With the Electronic Health Record
Diabetes is a significant medical problem in the United States and across the world. Despite significant progress in understanding how to better manage diabetes, there is oftentimes still uncertainty in the optimal management…
- Trial name
- NCT03826290
- Testing
- EHR-integrated diabetes dashboard
- Where
- United States
- Volunteers
- 13,155 people
- Sponsor
- University of Utah
Opioid Use, Unspecified
Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in Children.
The overall objective of this study is to evaluate strategies to reduce unused opioids prescribed for pediatric acute post-surgical pain management.
- Trial name
- NCT04219397
- Testing
- Medication take back, Medication home disposal
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mild Traumatic Brain Injury; Concussion
Seeing-Moving-Playing: Early Rehabilitation Utilizing Visual and Vestibular Technology Following Traumatic Brain Injury
The aim of this research program is to 1) Evaluate potential problems with vision, inner ear-eye reflexes and deficits of processing eye information that occur following TBI; and 2) Evaluate treatment programs for individuals…
- Trial name
- SiMPlyRehab (NCT03215082)
- Testing
- Vestibular-Visual Intervention, standard care
- Where
- 4 sites in Canada, France and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Opioid-use Disorder
Kentucky Women's Justice Community Opioid Innovation Network
This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and maintenance in the community following…
- Trial name
- W-JCOIN (NCT04069624)
- Testing
- MOUD Pre-Treatment Telehealth, MOUD Pre-Treatment Telehealth and Peer Navigator, Services as Usual
- Where
- 9 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Michele Staton
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