Clinical trials: Vehicle, completed
Ocular Redness
A Double-Masked Comparison of FID 123320 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness
The purpose of this study is to assess the safety and efficacy of Apraclonidine Hydrochloride Ophthalmic Solution 0.125% when compared to Vehicle, in relieving redness of the eye due to minor eye irritations.
- Trial name
- NCT06444529
- Testing
- Apraclonidine Hydrochloride Ophthalmic Solution, Vehicle
- Where
- 5 sites in United States
- Volunteers
- 159 people
- Sponsor
- Alcon Research
Recovery Following Partial Medial Meniscectomy
A Phase I/II Study of Chondrogen Delivered by Intra-Articular Injection Following Meniscectomy
The purpose of this study is to determine whether Chondrogen is a safe and effective post-operative treatment of the knee following menisectomy (the surgical removal of all or part of a torn meniscus).
- Trial name
- NCT00225095
- Testing
- Mesenchymal Stem Cells, Hyaluronan
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mesoblast International Sàrl
Dry Eye Disease
Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation
The objective of this study is to evaluate the safety and effectiveness of OC-01 Nasal Spray as compared to placebo in simulating Goblet Cell and Meibomian Gland function in adult subjects with DED.
- Trial name
- NCT03688802
- Testing
- OC-01 (varenicline) nasal spray
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Oyster Point Pharma, Inc.
Alpine Accident, Frostbite
10-years Nationwide Alpine Accidents in Austria
This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions.
- Conditions
- Alpine Accident, Frostbite, Cardiopulmonary Arrest With Successful Resuscitation, Lightning Injuries
- Trial name
- NCT03405467
- Testing
- general and specific data
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Bladder Cancer
The New England Bladder Cancer Study
Data from the new cancer atlas covering the period 1974 1994 indicates that deaths from bladder cancer among white men and women are elevated in the northeastern United States, particularly the northern parts of New England.
- Trial name
- NCT00342875
- Where
- United States
- Volunteers
- 2,681 people
- Sponsor
- National Cancer Institute (NCI)
Aqueous Tear Deficiency, Meibomian Gland Dysfunction of Bilateral Eyes (Disorder)
Eyelid Androgen Treatment in Dry Eye
The purpose of this research study is to evaluate the effectiveness and safety of applying androgen sex hormone (i.e., testosterone) gel on the eyelids in the treatment of dry eye patients.
- Trial name
- NCT06154200
- Testing
- Testosterone gel 4.5%, Vehicle gel
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Myeloma, Plasma-Cell, Myeloma-Multiple
Study of T Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma
Background: T cells are white blood cells that fight several cancers. One cancer therapy involves removing a persons' T cells, changing them in a lab, and then returning them to the person.
- Trial name
- NCT02215967
- Testing
- Cyclophosphamide, Fludarabine, Anti-B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Osteoarthritis of the Knee
Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee
The purpose of this trial is to investigate the efficacy and safety of OLT1177 Gel in subjects with moderate to severe pain associated with osteoarthritis of the knee following cessation of pain therapy.
- Trial name
- NCT01768975
- Testing
- OLT1177 Gel
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Olatec Therapeutics, Inc.
Primary Open Angle Glaucoma, Ocular Hypertension
A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.
To investigate dose response, safety and efficacy of PF-03187207 in patients with primary open-angle glaucoma or ocular hypertension
- Trial name
- NCT00595101
- Testing
- PF-03187207, Latanoprost 0.005%, PF-03187207 Vehicle
- Where
- 13 sites in Japan
- Volunteers
- 117 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye Syndrome
Efficacy and Safety Study of HU00701/HU007 Eye Drops in Patients With Dry Eye Syndrome
A multicenter, Placebo controlled, Restasis® referenced, Randomized, Double blind, Phase II Study to Evaluate the Efficacy and Safety of HU00701/HU007 Eye Drops in Adult Patients with Dry Eye Syndrome
- Trial name
- NCT02917512
- Testing
- HU00701, HU007, Restasis
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.
Psoriasis
Study to Evaluate the Efficacy and Safety of M518101 in Subjects With Plaque Psoriasis
This study is to evaluate the efficacy and safety of M518101 in subjects with plaque psoriasis.
- Trial name
- NCT01873677
- Testing
- M518101, Vehicle
- Where
- 31 sites in United States
- Volunteers
- 537 people
- Sponsor
- Maruho North America Inc.
Healthy
CC100: Safety and Tolerability of Single Doses
The purpose of this study is to see if CC100, given by mouth, is safe and is tolerated in increasing doses. How long the drug remains in the body will also be calculated.
- Trial name
- NCT02050334
- Testing
- CC100
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Chemigen, LLC
Rosacea
A Study to Evaluate the Safety, Tolerability, and Effects of Anatabloc® Crème in Rosacea
This is a multi-site, four-visit, eight-week, double-blind, randomized, vehicle-controlled, parallel-group study followed by an eight-week open-label extension to evaluate the safety, tolerability, and potential effects of…
- Trial name
- NCT01740934
- Testing
- Anatabloc Cream
- Where
- 3 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Rock Creek Pharmaceuticals, Inc.
Healthy
Clinical Evaluation of the Photoallergy Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes photoallergic reactions on the skin.
- Trial name
- NCT00645164
- Testing
- Ointment Vehicle, Xenaderm
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Diabetes Mellitus, Type 2
A Clinical Study to Assess the Effect of Food and Gender on the Pharmacokinetics of SRT2104 Administered as an Oral Suspension or Capsule Formulation to Normal Healthy Volunteers
The primary objective of this study is to assess the pharmacokinetic profile of a single 500 mg dose of SRT2104 administered as an oral suspension and a capsule formulation to normal healthy male and female volunteers in both the…
- Trial name
- NCT00938275
- Testing
- 0.5g SRT2104
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sirtris, a GSK Company
Chronic Hand Eczema
Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema
The purpose of this research trial was to test different strengths of a new trial medication, delgocitinib cream 1, 3, 8, and 20 mg/g, and to investigate how treatment with delgocitinib cream affects chronic hand eczema.
- Trial name
- NCT03683719
- Testing
- Delgocitinib cream, Delgocitinib cream vehicle
- Where
- 28 sites in United States, Denmark and 1 more
- Volunteers
- 258 people
- Sponsor
- LEO Pharma
Inflammatory Acne Vulgaris
Pivotal Study of Sebacia Microparticles in the Treatment of Acne Vulgaris
Prospective, randomized multicenter study to examine the safety and effectiveness of Sebacia microparticles with or without laser in the treatment of moderate to moderately-severe inflammatory acne vulgaris
- Trial name
- NCT02217228
- Testing
- Sebacia microparticles and laser, Vehicle suspension and laser, Sebacia microparticles without laser
- Where
- 19 sites in United States
- Volunteers
- 394 people
- Sponsor
- Sebacia, Inc.
Diabetic Polyneuropathy
Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy
Painful diabetic neuropathy is the most common cause of neuropathic pain. 0.075% topical capsaicin has been used to treat the pain, but there is no data in lower concentration.
- Trial name
- NCT00993070
- Testing
- Capsaicin
- Where
- Thailand
- Volunteers
- 33 people
- Sponsor
- Thammasat University
Blepharoptosis
Safety and Efficacy Study of RVL-1201 in Acquired Blepharoptosis
This is an exploratory, proof of concept study to evaluate the safety and efficacy of RVL-1201 dosed once or twice daily for 14 days compared to a placebo (vehicle) control in patients with ptosis.
- Trial name
- NCT01848041
- Testing
- RVL-1201
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- RVL Pharmaceuticals, Inc.
Photoaged Skin
Comparison of Metvix Photodynamic Therapy (PDT) With Its Vehicle in the Treatment of Photoaged Skin
Skin photoaging or skin photodamage were terms used to describe the change in the structure, function and appearance of skin caused by prolonged and repeated exposure to sunlight or other ultraviolet light sources.
- Trial name
- NCT00437320
- Testing
- Metvix Cream 160 mg/g, Metvix Vehicle Group
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 32 people
- Sponsor
- Galderma R&D
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