Clinical trials: Vehicle, completed
Actinic Keratosis
Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis
To compare the safety and efficacy profiles of AM001 Cream, 7.5% and its vehicle cream in the treatment of Actinic Keratosis (AK) Lesions
- Trial name
- NCT03210740
- Testing
- AM001 Cream, 7.5%, Vehicle Cream
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- AmDerma
Psoriasis Vulgaris
Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Psoriasis Vulgaris
The objective of the study is to compare the use of calcipotriol plus betamethasone dipropionate gel with betamethasone dipropionate in the gel vehicle, calcipotriol in the gel vehicle and the gel vehicle alone when used in…
- Trial name
- NCT00263718
- Testing
- Calcipotriol plus betamethasone dipropionate (LEO 80185) gel
- Where
- 5 sites in Canada, Germany and 3 more
- Volunteers
- 360 people
- Sponsor
- LEO Pharma
Nail Psoriasis
Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Nails Affected by Psoriasis
The purpose of this study is to confirm the clinical efficacy and the safety of P-3073 in patients affected by isolated psoriatic nail(s) and/or those with psoriatic nails and concomitant mild to moderate plaque psoriasis.
- Trial name
- NCT02606760
- Testing
- P-3073, Vehicle of P-3073
- Where
- 7 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 378 people
- Sponsor
- Polichem S.A.
Pharmacodynamic Response to Small Doses of Insulin
Transdermal Insulin Response In Healthy Volunteers
Bio-fermentation produced Human insulin is available without prescription in the U.S. This study is a physician-initiated trial of a formula enabling transdermal delivery of human insulin.
- Trial name
- NCT04857320
- Testing
- Human insulin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Transdermal Delivery Solutions Corp
Episodic Migraine Headache
A Multicenter Assessment of LBR-101 in High Frequency Episodic Migraine
The purpose of this study is to determine whether monthly subcutaneous administration of LBR-101 (fremanezumab) is safe and provides migraine prevention in subjects with high frequency episodic migraine.
- Trial name
- NCT02025556
- Testing
- LBR-101 High Dose, LBR-101 Low Dose
- Where
- 63 sites in United States
- Volunteers
- 297 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Secondarily Infected Traumatic Skin Lesions
To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Secondarily Infected Traumatic Skin Lesions
To compare the safety and efficacy of Perrigo's product to an FDA approved product, and to Compare Both Active Treatments to a Vehicle Control in the Treatment of Secondarily Infected Traumatic Skin Lesions
- Trial name
- NCT04155203
- Testing
- Mupirocin Calcium, Vehicle
- Where
- United States
- Volunteers
- 657 people
- Sponsor
- Padagis LLC
Healthy Volunteers
Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 2 of 4)
The purpose of this study is to evaluate the ability of PRT064445 to reverse the effects of several blood thinner drugs on laboratory tests. The study also is evaluating the blood levels of PRT064445 given at different doses.
- Trial name
- NCT03578146
- Testing
- PRT064445/Rivaroxaban
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Portola Pharmaceuticals
Lichen Simplex Chronicus
KM-001 Cream for Treatment of Pruritus in Adult Patients With Lichen Simplex Chronicus (LSC)
This is a phase 1, multi-center, randomized, vehicle-controlled, double-blinded, parallel-group study. Approximately 6 sites will conduct the study at Germany. Approximately 61 patients (male and female) planned to be screened.
- Trial name
- NCT05454462
- Testing
- IMP Application KM-001, Chemistry, Hematology
- Where
- 2 sites in Germany
- Volunteers
- 55 people
- Sponsor
- Orvida Pharma (formerly Kamari Pharma)
Head Lice Infestation
A Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation
The purpose of the study was to assess the efficacy, safety and tolerability of a single application of abametapir lotion 0.74% w/w compared to a vehicle control, when applied to the scalp and hair for 10 minutes at home.
- Trial name
- NCT02060903
- Testing
- Abametapir Lotion 0.74% w/w, Vehicle Lotion
- Where
- 7 sites in United States
- Volunteers
- 379 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Atopic Dermatitis
A Study to Evaluate the Safety and Efficacy of ATx201 in Subjects With Moderate Atopic Dermatitis
This is a Phase 2, 3-week, single-center, double-blind, randomized, two-arm, vehicle controlled study, with each individual receiving both active and vehicle treatment.
- Trial name
- NCT03304470
- Testing
- ATx201 2% Cream, ATx201 Cream Vehicle
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- UNION therapeutics
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a phototoxic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01115322
- Testing
- Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Allergic Contact Dermatitis
Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis
The purpose of this study is to evaluate the safety and efficacy of EB01 Cream (0.2%, 1.0%, 2.0%) applied twice per day (BID) for the treatment of moderate to severe chronic allergic contact dermatitis (ACD).
- Trial name
- NCT03680131
- Testing
- EB01 Cream 0.2%, EB01 Cream 1.0%, EB01 Cream 2.0%
- Where
- 15 sites in United States, Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Edesa Biotech Inc.
Dry Eye
A Clinical Trial to Assess Subjects With Dry Eye Disease.
A Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease
- Trial name
- NCT04971031
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Vehicle Ophthalmic Solution
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Acute Viral Conjunctivitis
FST-100 in the Treatment of Acute Viral Conjunctivitis
This randomized, double masked, multi-center study is being conducted to support the safety and efficacy of FST-100 for the treatment of acute viral conjunctivitis.
- Trial name
- NCT01461954
- Testing
- FST-100, FST-100 Vehicle
- Where
- 2 sites in United States, Brazil
- Volunteers
- 132 people
- Sponsor
- Shire
Mild Cognitive Impairment
Effects of a Nutraceutic Compound on Cognitive Impairment
The study is designed to evaluate the effects of choline bitartrate on cognitive impairment in frailty patients. The study will analyze the impact of 4 weeks treatment randomized with a nutraceutical compound in a double-blind…
- Trial name
- ENUCCI (NCT06200883)
- Testing
- Choline Bitartrate
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Federico II University
Head Lice
NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers
Photoallergic reactions are assumed to be due to a delayed cell-mediated hypersensitivity response that requires the presence of ultraviolet irradiation.
- Trial name
- NCT00605956
- Testing
- NatrOVA Creme Rinse - 1%, NatrOVA Creme Rinse Vehicle Only, Blank Patch
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ParaPRO LLC
Scabies
A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies
To determine and compare the safety and efficacy of permethrin foam 4% and permethrin foam 5% with that of vehicle in subjects with scabies.
- Trial name
- NCT02094716
- Testing
- Permethrin Foam 4%, Permethrin Foam 5%, Vehicle Foam
- Where
- 9 sites in United States, Dominican Republic and 2 more
- Volunteers
- 130 people
- Sponsor
- Mylan Inc.
Secondarily Infected Traumatic Skin Lesions
A Study to Evaluate the Safety and Bioequivalence of Mupirocin Calcium Cream, 2% and Bactroban® Cream and Compare Both to a Vehicle in Treatment of Secondarily Infected Traumatic Skin Lesions.
The primary objective of this study is to determine the comparability of the safety and efficacy of Mupirocin Calcium Cream, 2% and Bactroban® Cream in subjects with secondarily infected traumatic skin lesions.
- Trial name
- NCT01876550
- Testing
- Mupirocin Calcium Cream, 2%, Bactroban® Cream, Cream vehicle of test product
- Volunteers
- 1,902 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
A Study to Evaluate the Safety and Efficacy of CB-03-01 Cream, 1% in Subjects With Facial Acne Vulgaris (26)
The primary objective of this study is to determine the safety and efficacy of CB-03-01 cream, 1%, versus the vehicle cream applied twice daily for 12 weeks in subjects with facial acne vulgaris.
- Trial name
- NCT02608476
- Testing
- CB-03-01 cream, 1%, Vehicle cream
- Where
- 52 sites in United States, Bulgaria and 4 more
- Volunteers
- 732 people
- Sponsor
- Cassiopea SpA
External Anogenital Warts
Comparison Between Podofilox Topical Gel 0.5% and Allergan's Condylox® Gel 0.5% for External Anogenital Warts
A clinical endpoint bioequivalence (BE) study for a Podofilox Gel 0.5% formulation for the treatment of external anogenital warts in comparison to Condylox® Gel 0.5% that follows the study design and recommendations according to…
- Trial name
- NCT03532776
- Testing
- Podofilox Gel 0.5%, Condylox Topical Gel 0.5%
- Where
- 17 sites in United States, Russia and 1 more
- Volunteers
- 466 people
- Sponsor
- Dermax SA
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.