Clinical trials: Vitamin C
Wounds and Injuries, Malnutrition
Individualized Nutritional Care Bundle for Home Nursing Patients With Pressure Injuries.
Objective: To evaluate the impact of an individualized nutrition intervention package on pressure injury healing rates, prevention of new pressure injuries, complications, quality of life, and cost-effectiveness in adult on home…
- Conditions
- Wounds and Injuries, Malnutrition, Nutritional Deficiency, Wound Healing Delayed
- Trial name
- INCA (NCT06078488)
- Testing
- Individualized and Protocolized Nutritional Care Bundle, Optimized Standard Care
- Where
- Singapore
- Volunteers
- 380 people
- Sponsor
- Changi General Hospital
Gingival Hyperpigmentation, Gingival Melanin Pigmentation
Vitamin C for Gingival Depigmentation
The purpose of this study is to evaluate the clinical and histopathological efficacy of topical vitamin C applications using three modalities (topical gel, microneedling , and mesotherapy) in gingival depigmentation.
- Trial name
- VitC-DePg (NCT07513727)
- Testing
- Topical Vitamin C ( control Arm), Vitamin C mesotherapy, Microneedling technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Frail Elderly Syndrome
Management of Frailty in Older Adults With Turmeric and Tulsi Supplements
The aim of this study is to determine the efficacy of turmeric and tulsi polyherbal formulation in the management of frailty in the elderly population.
- Trial name
- NCT03365310
- Testing
- C. longa, curcuminoids , Z. officianale, O. sanctum along with 200 ml of Milk, Standard of Care
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Composite Interceptive Med Science
Sepsis, Septic Shock
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock
A great interest exists regarding substances with an immunomodulatory effect for sepsis patients. Recent data have shown that intravenous vitamin C, together with corticosteroids and thiamine, could prevent progressive organ…
- Trial name
- NCT05192213
- Testing
- Vitamin C
- Where
- 12 sites in Brazil
- Volunteers
- 71 people
- Sponsor
- Hospital Sirio-Libanes
Iron Absorption, Gut Microbiota
Iron Absorption From a Wheat-based Instant Cereal:Gut and Stable Isotope Studies in Kenyan Infants
The aim of this study is to measure the effect of a prebiotic (high dose/low dose) mixture at different doses within a wheat-based instant cereal, on fractional iron absorption (FIA), gut microbiota and inflammation after three…
- Trial name
- NCT03894358
- Testing
- FeFum and 7.5 g prebiotic mixture, FeFum and 3 g prebiotic mixture, Fefum and no prebiotic mixture
- Where
- Kenya
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pain, Acute
Impact of Vitamin C on Pain Detection and Tolerance Threshold
Non-opioid treatments are increasingly sought after for managing acute pain. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Advil, Motrin, Naproxen) combined with acetaminophen (e.g., Tylenol) have become an alternative…
- Trial name
- NCT06971315
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Imparied Retinal Vascular Reactivity, Healthy Subjects
Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans
Oxidative stress has been implicated to play a pathogenic role in many disease processes, especially in age-related disorders such as age-related macular degeneration.
- Trial name
- NCT02221089
- Testing
- Escherichia coli Endotoxin, Retaron®
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Critical Illness, Sepsis
Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients
The purpose of this study is to determine whether providing high dose glutamine and antioxidants to critically ill patients will be associated with improved survival.
- Conditions
- Critical Illness, Sepsis, Multiple Organ Failure
- Trial name
- REDOXS (NCT00133978)
- Testing
- Glutamine, Antioxidants, Glutamine + Antioxidants
- Where
- 34 sites in United States, Belgium and 3 more
- Volunteers
- 1,223 people
- Sponsor
- Daren K. Heyland
Calcium and Vitamin D Deficiencies
Calcichew D3 Preference Study in Participants Eligible for Calcium and Vitamin D Supplementation.
The purpose of this study is to compare the preference of Calcichew D3 500/400 (containing 500 mg calcium and 400 IU of vitamin D) with Adcal-D3 600/400 (containing 600 mg of calcium and 400 IU of vitamin D) in Test Group 1, and…
- Trial name
- NCT02457247
- Testing
- Calcichew D3, Adcal-D3, Kalcipos-D
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 276 people
- Sponsor
- Takeda
Contrast Induced Nephropathy
Contrast Agent-associated Nephrotoxicity in Intensive Care Unit Patients
The use of N-acetylcysteine and ascorbic acid reduce the incidence of radiographic contrast agent induced reduction in renal function in Intensive Care Unit patients.
- Trial name
- ICU (NCT01017796)
- Testing
- N-acetylcysteine and ascorbic acid
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Recurrent Urinary Tract Infection
Nutritional Supplementation for Recurrent Urinary Tract Infections in Women
The study will test the ability of specially formulated nutritional supplement capsules to extend the time between recurrent urinary tract infections in women.
- Trial name
- NCT03597152
- Testing
- WelTract
- Volunteers
- 250 people
- Sponsor
- AmPurity Nutraceuticals, LLC
RNA Virus Infections, Flaviviridae Infections
Vitamin D and Vitamin B12 Supplementation With Pegylated Interferon-Alfa Plus Ribavirin for Treating Chronic Hepatitis C
The purpose of this study is to evaluate the effectiveness of the supplementation of vitamins D and B12 in combination with Pegylated Interferon-Alfa and Ribavirin in the treatment of genotype 1 chronic hepatitis C, who do not…
- Conditions
- RNA Virus Infections, Flaviviridae Infections, Hepatitis C, Hepatitis C, Chronic
- Trial name
- NCT02120274
- Testing
- Vitamin D, Vitamin B 12
- Where
- Brazil
- Volunteers
- 85 people
- Sponsor
- Federal University of São Paulo
Sepsis, Vitamin C
Lessening Organ Dysfunction With VITamin C
LOVIT is a multicentre concealed-allocation parallel-group blinded randomized controlled trial to ascertain the effect of high-dose intravenous vitamin C compared to placebo on mortality or persistent organ dysfunction at 28 days…
- Conditions
- Sepsis, Vitamin C, Intensive Care Unit, COVID-19
- Trial name
- LOVIT (NCT03680274)
- Testing
- Vitamin C, Control
- Where
- Canada
- Volunteers
- 872 people
- Sponsor
- Université de Sherbrooke
Stroke Patients With Constipation
A Study on the Effect of Electronic Moxibustion Based on Ziwu Liuzhu in Treating Constipation in Stroke Patients
This study aims to explore the application effect of Ziwu Liuzhu electronic moxibustion combined with auricular points on constipation in stroke patients through clinical controlled trials, as well as the advantages over using…
- Trial name
- NCT07372326
- Testing
- Electronic moxibustion instrument, An electronic moxibustion device under the guidance of the Yuziuyouluo theory
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
HIV Infections, Disease Transmission, Vertical
Trial of Vitamins in HIV Progression and Transmission
This study tested the hypothesis that multivitamin supplementation given to HIV+ pregnant women in Tanzania would slow disease progression and enhance their overall health.
- Trial name
- NCT00197743
- Testing
- Vitamin A + Beta Carotene, Multivitamins
- Where
- United States
- Volunteers
- 1,085 people
- Sponsor
- Harvard School of Public Health (HSPH)
Aging
Oxidative Stress Links Aging, Activity, and Mobility Limitation
The purpose of this study is to understand why and how oxidative stress negatively impacts mobility in the elderly, and to determine whether antioxidant supplements can increase vascular health and mobility.
- Trial name
- NCT01177189
- Testing
- Vitamins C, E, and alpha lipoic acid
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Liver Metastases
AvidinOX + [177Lu]DOTA-biotin (or 177Lu-ST2210) Complex in Patients With Liver Metastases From Colorectal Cancer
The purpose of the study is to assess a new treatment for patients with liver tumor metastases from colorectal cancer. The treatment has never been used in humans before.
- Trial name
- NCT02053324
- Testing
- AvidinOX/ST2210
- Where
- 4 sites in Austria, Italy
- Volunteers
- 14 people
- Sponsor
- Alfasigma S.p.A.
Immediate Dental Implant
The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region
The concept of immediate implant placement at the time of tooth extraction was first introduced by Schulte et al. on animal studies.
- Trial name
- NCT03804177
- Testing
- immediate implant placement with melatonin hyaluronic acid vit C, immediate implant placement without melatonin hyaluronic acid vit C
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endothelial Function, Cognition
Cognitive and Cerebral Blood Flow Effects of Vitamin C
This investigation is interested in the effects of high dose vitamin C on endothelial function in healthy humans. A high fat meal will be utilized to induce endothelial dysfunction.
- Trial name
- NCT01055418
- Testing
- Vitamin C
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Breast Cancer, Triple Negative Breast Cancer
Viscum Album for TNBC on Adjuvant Pembrolizumab
The goal of this clinical trial is to evaluate the efficacy and safety of Viscum album extract when used in combination with pembrolizumab as adjuvant chemotherapy in adult patients (aged 19 and older) who have been diagnosed…
- Trial name
- TNBNOBA (NCT06920810)
- Testing
- viscum album
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ilsan Cha hospital
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