Clinical trials: Vitamin C
Iron-deficiency, Vitamin A Deficiency
Sub Regional Micronutrient Survey in Ethiopia
To conduct a sub-regional micronutrient survey (SRMNS) assessing the prevalence of vitamin A, Zn, and Fe status in the country
- Conditions
- Iron-deficiency, Vitamin A Deficiency, Zinc Deficiency
- Trial name
- NCT03353662
- Testing
- Women of Gamo Gofa, Children of Gamo Gofa, Women of West Gojjam
- Where
- 2 sites in Ethiopia, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Diabetes Mellitus, Type 1
Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study B
Glutathione is normally present at high levels in the blood and plays an important role in the body's defense against oxidative stress, that is, against the damage caused to the body by several reactive oxygen species produced by…
- Trial name
- NCT00858273
- Testing
- Antioxidant supplement, Diabetes treatment, Regular Insulin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Nemours Children's Clinic
Labor Onset and Length Abnormalities
Misoprostol Versus Oxytocin for Induction of Labour in Parturients With Spontaneous Rupture of Fetal Membranes at Term
Intravenous oxytocin titration has a prime position as a choice agent for induction of labour following term PROM as it has been shown to be efficacious for such purpose.
- Trial name
- NCT06343480
- Testing
- Labour Induction
- Where
- 2 sites in Nigeria
- Volunteers
- 120 people
- Sponsor
- Federal Teaching Hospital Abakaliki
H1N1 Influenza
The Impact of Vitamin on the Clinical Course in Cases Infected by Novel H1N1 Influenza Virus A
Influenza continues to inflict an important burden on health-care systems. The 2009 H1N1 influenza virus first appeared in Mexico and the United States in March and April 2009 and has swept the globe with unprecedented speed.
- Trial name
- NCT01127282
- Testing
- Vitamin (vitamin A 15 mg,C 500 mg, E 400IU)
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Seoul National University Hospital
Orthopedic Disorder, Hip Arthropathy
Iron Supplementation in Hip/Knee Surgery
Randomized controlled trial to evaluate the efficacy of oral iron supplementation in reducing the prevalence of preoperative anemia in a cohort of 82 patients undergoing elective prosthetic hip or knee surgery.
- Conditions
- Orthopedic Disorder, Hip Arthropathy, Knee Arthropathy, Anemia
- Trial name
- NCT04078880
- Testing
- Sucrosomial iron plus ascorbic acid
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
OSTEOPENIA
Functional Yogurt Powder Effect on Bone Health Biomarkers
The purpose of this study was to evaluate the therapeutic effect of a functional yogurt powder on menopausal, middle-aged women at high risk of osteoporosis.
- Trial name
- bonefoods (NCT02629341)
- Testing
- Functional yogurt powder, Control yogurt powder
- Where
- Spain
- Volunteers
- 79 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pregnant Women, Preeclampsia
Antioxidant Supplementation in Pregnant Women
The purpose of this study is to investigate the benefit of several micro nutrients of antioxidants (using milk) in a cohort of women with low antioxidant status and the changes in cell-free mRNA.
- Trial name
- ASIP1 (NCT01232205)
- Testing
- micronutrient antioxidant, Control
- Where
- Indonesia
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Showa University
Obese, Disorder of Vitamin C
The Effect of Vitamin C on Growth Hormone Secretion
Obesity is associated with reduced growth hormone (GH) secretion. GH secretion is regulated by nutritional stimuli including fasting, insulin, glucose and free fatty acids.
- Conditions
- Obese, Disorder of Vitamin C, Growth Hormone Secretion Abnormality
- Trial name
- NCT01537094
- Testing
- Vitamin C 250 mg once daily, Vitamin C 1,000 mg once daily
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Effect of Food Supplement
Effects of Vitamin C Enriched Hydrolyzed Collagen, PrimaColl™, Whey Protein, or Placebo on Collagen Synthesis
The purpose of this study is to determine the effects of repeated dosing vitamin C enriched hydrolyzed collagen (HC) over a 24hr period, compared to PrimaColl™ (PC), whey protein (WP) and placebo (PL), with prescribed exercise on…
- Trial name
- NCT05427279
- Testing
- Hydrolized Collagen, PrimaColl, Whey protein
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hair Thinning
Efficacy of the New Viviscal Professional Strength Oral Supplement in Females With Thinning Hair
The New Viviscal Professional Strength is an oral food supplement specifically designed to promote hair growth for women suffering from temporary thinning hair. It does not contain hormones, drugs or industry by-products.
- Trial name
- NCT02302053
- Testing
- New Viviscal Professional Supplement
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ablon Skin Institute Research Center
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia-1
Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies
The primary purpose of this multi-centre, randomized, placebo-controlled, double-blind phase II study is to investigate if oral vitamin C may change the biology of low-risk myeloid malignancies; i.e., clonal cytopenia of…
- Conditions
- Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia-1, Cytopenia
- Trial name
- EVITA (NCT03682029)
- Testing
- Vitamin C (ascorbic acid)
- Where
- 5 sites in United States, Denmark
- Volunteers
- 109 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Secondary Hyperparathyroidism, End Stage Renal Disease
A Study to Follow-up Patients With End Stage Renal Disease Undergoing Hemodialysis, Receiving Selective Vitamin D Receptor Activator's for Prevention and Treatment of Secondary Hyperparathyroidism
The aim of this post-marketing observational study is to obtain further data on the long term use, safety and efficacy of selective Vitamin D Receptor Activator's as it is prescribed in the normal clinical setting and according…
- Trial name
- NCT01149291
- Where
- 22 sites in Turkey (Türkiye)
- Volunteers
- 511 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Disorder of Vitamin C, Atrial Fibrillation
High Dose Vitamin C in Cardiac Surgery Patients
Coronary artery bypass grafting (CABG) is the most common procedure performed by cardiac surgeons. Post-operative atrial fibrillation (AF) is the most common adverse event following CABG, experienced in 20-50% of patients; the…
- Conditions
- Disorder of Vitamin C, Atrial Fibrillation, Complications Due to Coronary Artery Bypass Graft, Heart Valve Disease
- Trial name
- NCT02762331
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Virginia Commonwealth University
Healthy
Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers
Primary: To quantify the influence of single-dose and steady-state tipranavir/ritonavir 500/200 mg on intestinal and hepatic cytochrome P450 (CYP) and P-glycoprotein (P-gp) biomarkers, as a means of predicting drug interactions.
- Trial name
- NCT02243553
- Testing
- Tipranavir capsule, Tipranavir solution, Ritonavir capsule
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Burn
Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment.
Eye burns may cause a severe permanent damage. One kind of treatment is the use of vitamin C (Ascorbic acid). This study will compare between subconjunctival topical and/or systemic route of administration and topical and/or…
- Trial name
- NCT00734695
- Testing
- vitamin c
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Prodromal Schizophrenia
Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis Risk
This study will investigate whether a single dose of diazepam (5mg) compared to placebo can modulate brain chemistry (GABA/glutamate levels) and function (blood flow, neural response and connectivity during tasks and at-rest) in…
- Trial name
- BENZOGAP (NCT06190483)
- Testing
- Diazepam 5 Mg Oral Tablet, Ascorbic Acid 50 Mg Oral Tablet
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London
Temporomandibular Disorders
Oxidative Stress and Opiorphin in Temporomandibular Disorders
The objective of this study is to quantify salivary oxidative stress biomarkers in patients with temporomandibular disorders and to quantify recently isolated endogenous peptide opiorphin in saliva of these patients.
- Trial name
- ROStrO-TMD (NCT03029494)
- Testing
- stabilization splint, Vitamin C
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
Alopecia Areata
Combined Microneedling With Either 1% Lactic Acid Solution or Vitamin D3 or Triamcinolone Acetonide in The Treatment of Alopecia Areata
Alopecia areata (AA) is an immunologically mediated disease characterized by non-scarring hair loss (Madni and Shapiro, 2000). AA is presented by rapid and complete hair loss in one or more round or oval patches, usually on the…
- Trial name
- NCT06327581
- Testing
- Lactic Acid, vit D, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Zagazig University
Septic Shock
Vitamin C Deficiency in Septic Shock
Objectives: investigators aim to study the effect of addition of vitamin C as a part of treatment in septic shock patients on: Hemodynamics, Inflammation status and ICU outcome.
- Trial name
- NCT06224881
- Testing
- Ascorbic acid
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
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